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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Circular RNA circATP9A promotes non-small cell lung cancer progression by interacting with HuR and by promoting extracellular vesicles-mediated macrophage M2 polarization

Fig. 6

circATP9A governs NSCLC growth and metastasis by stabilizing NUCKS1 mRNA in vitro. Notes: A, B The NUCKS1 mRNA and protein level analyzed by qRT-PCR and western blot after re-express NUCKS1 in circATP9A knockdown NSCLC cells; C, D CCK8 assays for effects of NUCKS1 re-expression on proliferation of A549 and H1299 cells with circATP9A knockdown; E Colony formation assay for effects of NUCKS1 re-expression on proliferation of A549 and H1299 cells with circATP9A knockdown; F Transwell assay for effects of NUCKS1 re-expression on invasion and migration of A549 and H1299 cells with circATP9A knockdown; G fgsea analysis of NUCKS1 in NSCLC; H The protein level of the markers of PI3K/AKT/mTOR signaling in the A549 and H1299 cells with NUCKS1 re-expression with circATP9A knockdown

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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