Fig. 1From: Caloric restriction and metformin selectively improved LKB1-mutated NSCLC tumor response to chemo- and chemo-immunotherapyTreatment schedule of in vivo experiments: A Mice were treated with chemotherapy (DDP) alone or in combination with metformin and caloric restriction (CR). B Mice were treated with chemotherapy (DDP) plus immunotherapy (anti PD-1) alone or in combination with metformin and caloric restriction (CR)Back to article page