Fig. 9From: DCAF13 inhibits the p53 signaling pathway by promoting p53 ubiquitination modification in lung adenocarcinomaA model diagram of DCAF13 promotes p53 protein ubiquitination degradation via CRL4 complex, which in turn inhibits the p53 signaling pathway, leading to the altered histone modifications of CDKN1A, BAX and FAS, and ultimately promotes LUAD progressionBack to article page