Fig. 8

PHB2 expression is negatively correlated with SHIP2 expression, and positively correlated with p-Akt and Ki67 expression in GC. A representative photograph showed the expression of PHB2, SHIP2, p-Akt, and Ki67 in GC tissues and adjacent normal tissues examined by IHC staining (n = 15). Scale bar: 200 μm. B-D the expression correlations between PHB2 and SHIP2 (B), PHB2 and p-Akt (C), and PHB2 and Ki67 (D) depicted in A were analysed using using Pearson’s correlation coefficient test. n = 15 clinical samples. E, F the expression correlations between PHB2 and SHIP2 (E), and PHB2 and Ki67 (F) in GC tissues from the Human Protein Atlas dataset (https://www.proteinatlas.org) were analysed using Pearson’s correlation coefficient test. n = 9 clinical samples. G Western blotting analysis of PHB2, SHIP2, p-Akt, and GAPDH protein expression in gastric tumour (T) patient samples and paired adjacent normal (N) gastric tissues. Data are representatives