Fig. 6

PRMT6 Facilitates Migration, Invasion, and EMT in Glioma via YTHDF2. A: Protein expression analysis of PRMT6 and YTHDF2 in LN229 and U251 cell lines, where YTHDF2 is reintroduced in a PRMT6 knockdown context. B-D: Scratch assays to assess migration rates in LN229 and U251 cells upon YTHDF2 rescue in the PRMT6 knockdown background. E-F: Transwell assays to evaluate cell migration and invasion following YTHDF2 re-expression in PRMT6 knockdown LN229 and U251 cells. Scale bar = 200 μm. G: Assessment of EMT marker proteins E-cadherin, N-cadherin, and Vimentin in LN229 and U251 cells post-rescue of YTHDF2 on a PRMT6 knockdown framework