Fig. 5

Survival prognostication of LM.SIG. (A) Comparison of C-index plots depicting the performance of 15 ML algorithms in the validation set. (B) Line Graph illustrating the distribution of model fitness in the MTLR_GA method. (C) Comparison of C-index plots depicting the performance of the LM.SIG prognostic model in the validation and testing sets. (D) Kaplan‑Meier curves comparing OS between High‑risk and Low‑risk patients in the training, validation and testing sets