Fig. 7

MFSD12 is upregulated in NSCLC and associated with unfavorable prognosis. A ENCORI database analysis depicting the MFSD12 mRNA expression in LUAD and LUSC tissues. B Kaplan–Meier analysis illustrating the negative relationship between MFSD12 expression and overall survival (OS) rates of LUAD and LUSC patients. C Proposed working model depicting the mechanism by which tumor-suppressive miR-4732-3p is sorted into fucosylated exosomes through its interaction with hnRNPK protein, thereby promoting NSCLC progression. Data are shown as the mean ± SD from at least three independent experiments. ^****p < 0.0001