Table 1 Relationship between general clinical characteristics and circPDE5A level in patients with ESCC (n = 100)
General clinical characteristics | CircPDE5A expression | p-value | statistics | |
|---|---|---|---|---|
High (n = 50) | Low (n = 50) | |||
Gender (%) | Â | Â | 1 | 0 |
 Female | 44 (88) | 44 (88) |  |  |
 Male | 6 (12) | 6 (12) |  |  |
Age (mean ± SD) | 58.6 ± 10.367 | 60.22 ± 10.938 | 0.449 | -0.760 |
BMI (mean ± SD) | 23.103 ± 4.12 | 22.752 ± 3.62 | 0.652 | 0.453 |
Smoke history (%) | 22 (44) | 28 (52) | 0.423 | 0.641 |
Alcohol history (%) | 35 (70) | 29 (58) | 0.211 | 1.563 |
Histologic Grade (G stage) (%) |  |  | 0.249 | 1.329 |
 G1 | 9 (18) | 5 (10) |  |  |
 G2 + G3 | 41 (82) | 45 (90) |  |  |
T stage | Â | Â | 0*** | 17.818 |
 T1 + T2 | 33 (66) | 12 (24) |  |  |
 T3 + T4 | 17 (34) | 38 (76) |  |  |
N stage | Â | Â | 0*** | 14.586 |
 N0 | 32 (64) | 13 (26) |  |  |
 N1 + N2 + N3 | 18 (36) | 37 (74) |  |  |
M stage | Â | Â | 0.056 | 5.263a |
 M0 | 50 (100) | 45 (90) |  |  |
 M1 | 0 (0) | 5 (10) |  |  |
TNM stage | Â | Â | 0*** | 36.946 |
 I + II | 44 (88) | 14 (28) |  |  |
 III + IV | 6 (12) | 36 (72) |  |  |