Skip to main content

Table 2 The deregulated DEGs sharing from cirrhosis to metastasis stage classified by the following screened GO.

From: Characteristic gene expression profiles in the progression from liver cirrhosis to carcinoma induced by diethylnitrosamine in a rat model

Functional Categories

Number Of Annotated Genes

 

12th week

14th week

16th week

20th week

4 group

Metabolism

334/318

403/324

541/446

494/375

206/198

Transport

162/164

188/167

264/225

229/195

101/106

Cell Growth

129/88

161/86

207/104

218/88

89/51

Cell Differentiation

103/57

127/67

170/69

171/69

72/35

Apoptosis

87/50

113/48

128/62

153/46

59/28

Angiogenesis

12/11

15/13

23/15

25/14

9/6

Cell Proliferation

68/51

93/57

108/57

115/54

46/36

Cell Migration

13/12

15/15

30/13

25/13

10/8

Cell Adhesion

62/25

76/30

106/30

94/30

40/13

Extracellular Matrix

41/21

48/22

61/29

73/23

26/14

Oxidative Stress

31/19

41/24

43/27

50/26

23/12

Immune Response

30/25

34/23

38/35

35/28

19/16

Inflammatory Response

12/17

18/20

17/31

18/21

7/11

Cytochrome

19/30

23/28

29/45

25/38

11/20

Signal Transduction

140/106

165/111

243/129

213/115

87/59

Protein Kinase

114/67

128/77

193/95

185/73

65/38

Proteasome

17/6

20/8

25/7

19/6

13/4

  1. NOTE: The words '12th week, 14th week, 16th week, 20th week' in the table indicate the cirrhosis tissue, dysplastic nodules, early cancerous nodules and cancerous nodules with metastasis, respectively. The word '4 group' means the DEGs sharing for the above 4 stages of liver tissues. The numbers up and down the line indicate the number of up-regulated and down-regulated DEGs respectively.
Back to article page

Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

Contact us