Figure 4

Effect of pGenesil-CENP-E on chromosome sepration in LO ₂ cells. (A) shows that karyotype of LO2 cells, tetraploid (middle) and subdiploid karyotype (right) present in pGenesil-CENPE mediated LO₂ cells. (fig 4A). (B) aneuploid cells in the LO2 cells treated with shRNA vector is largely high, compare with cells transfected with scrambler control shRNA vector or mock. Data represent the mean ± S.E. of three independent experiments. *, P < 0.05 versus mock; ^#, P > 0.05 versus mock; (fig 4B)