Jallepalli PV, Lengauer C: Chromosome segregation and cancer: cutting through the mystery. Nat Rev Cancer. 2001, 1 (2): 109-117. 10.1038/35101065.
Article
CAS
Google Scholar
Wassmann K, Benezra R: Mitotic checkpoints: from yeast to cancer. Curr Opin Genet Dev. 2001, 11 (1): 83-90. 10.1016/S0959-437X(00)00161-1.
Article
CAS
Google Scholar
Cleveland DW, Mao Y, Sullivan KF: Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling. Cell. 2003, 112 (4): 407-421. 10.1016/S0092-8674(03)00115-6.
Article
CAS
Google Scholar
Chan GK, Jablonski SA, Sudakin V, Hittle JC, Yen TJ: Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC. J Cell Biol. 1999, 146 (5): 941-954. 10.1083/jcb.146.5.941.
Article
CAS
Google Scholar
Chan GK, Schaar BT, Yen TJ: Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1. J Cell Biol. 1998, 143 (1): 49-63. 10.1083/jcb.143.1.49.
Article
CAS
Google Scholar
Mao Y, Abrieu A, Cleveland DW: Activating and silencing the mitotic checkpoint through CENP-E-dependent activation/inactivation of BubR1. Cell. 2003, 114 (1): 87-98. 10.1016/S0092-8674(03)00475-6.
Article
CAS
Google Scholar
Lombillo VA, Nislow C, Yen TJ, Gelfand VI, McIntosh JR: Antibodies to the kinesin motor domain and CENP-E inhibit microtubule depolymerization-dependent motion of chromosomes in vitro. J Cell Biol. 1995, 128 (1-2): 107-115. 10.1083/jcb.128.1.107.
Article
CAS
Google Scholar
Yao X, Anderson KL, Cleveland DW: The microtubule-dependent motor centromere-associated protein E (CENP-E) is an integral component of kinetochore corona fibers that link centromeres to spindle microtubules. J Cell Biol. 1997, 139 (2): 435-447. 10.1083/jcb.139.2.435.
Article
CAS
Google Scholar
Putkey FR, Cramer T, Morphew MK, Silk AD, Johnson RS, McIntosh JR, Cleveland DW: Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E. Dev Cell. 2002, 3 (3): 351-365. 10.1016/S1534-5807(02)00255-1.
Article
CAS
Google Scholar
McEwen BF, Chan GK, Zubrowski B, Savoian MS, Sauer MT, Yen TJ: CENP-E is essential for reliable bioriented spindle attachment, but chromosome alignment can be achieved via redundant mechanisms in mammalian cells. Mol Biol Cell. 2001, 12 (9): 2776-2789.
Article
CAS
Google Scholar
Schaar BT, Chan GK, Maddox P, Salmon ED, Yen TJ: CENP-E function at kinetochores is essential for chromosome alignment. J Cell Biol. 1997, 139 (6): 1373-1382. 10.1083/jcb.139.6.1373.
Article
CAS
Google Scholar
Yao X, Abrieu A, Zheng Y, Sullivan KF, Cleveland DW: CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint. Nat Cell Biol. 2000, 2 (8): 484-491. 10.1038/35019518.
Article
CAS
Google Scholar
Sze KM, Ching YP, Jin DY, Ng IO: Association of MAD2 expression with mitotic checkpoint competence in hepatoma cells. J Biomed Sci. 2004, 11 (6): 920-927. 10.1007/BF02254377.
Article
CAS
Google Scholar
Sze KM, Ching YP, Jin DY, Ng IO: Role of a novel splice variant of mitotic arrest deficient 1 (MAD1), MAD1beta, in mitotic checkpoint control in liver cancer. Cancer Res. 2008, 68 (22): 9194-9201. 10.1158/0008-5472.CAN-08-2600.
Article
CAS
Google Scholar
Jeong SJ, Shin HJ, Kim SJ, Ha GH, Cho BI, Baek KH, Kim CM, Lee CW: Transcriptional abnormality of the hsMAD2 mitotic checkpoint gene is a potential link to hepatocellular carcinogenesis. Cancer Res. 2004, 64 (23): 8666-8673. 10.1158/0008-5472.CAN-03-3455.
Article
CAS
Google Scholar
Marchio A, Meddeb M, Pineau P, Danglot G, Tiollais P, Bernheim A, Dejean A: Recurrent chromosomal abnormalities in hepatocellular carcinoma detected by comparative genomic hybridization. Genes Chromosomes Cancer. 1997, 18 (1): 59-65. 10.1002/(SICI)1098-2264(199701)18:1<59::AID-GCC7>3.0.CO;2-0.
Article
CAS
Google Scholar
Li YM, Liu XH, Cao XZ, Wang L, Zhu MH: Expression of centromere protein A in hepatocellular carcinoma. [Article in Chinese]. Zhonghua Bing Li Xue Za Zhi. 2007, 36 (3): 175-8.
CAS
Google Scholar
Tomonaga T, Matsushita K, Yamaguchi S, Oohashi T, Shimada H, Ochiai T, Yoda K, Nomura F: Overexpression and mistargeting of centromere protein-A in human primary colorectal cancer. Cancer Res. 2003, 63 (13): 3511-6.
CAS
Google Scholar
O'Brien SL, Fagan A, Fox EJ, Millikan RC, Culhane AC, Brennan DJ, McCann AH, Hegarty S, Moyna S, Duffy MJ, Higgins DG, Jirström K, Landberg G, Gallagher WM: CENP-F expression is associated with poor prognosis and chromosomal instability in patients with primary breast cancer. Int J Cancer. 2007, 120 (7): 1434-43. 10.1002/ijc.22413.
Article
Google Scholar
Wen-Ting Liao, Chun-Ping Yu, Dong-Hui Wu, Ling Zhang, Li-Hua Xu, Gui-Xiang Weng, Mu-Sheng Zeng, Li-Bing Song, Jin-Song Li: Upregulation of CENP-H in tongue cancer correlates with poor prognosis and progression. J Exp Clin Cancer Res. 2009, 28 (1): 74-
Article
Google Scholar
Liao WT, Song LB, Zhang HZ, Zhang X, Zhang L, Liu WL, Feng Y, Guo BH, Mai HQ, Cao SM, Li MZ, Qin HD, Zeng YX, Zeng MS: Centromere protein H is a novel prognostic marker for nasopharyngeal carcinoma progression and overall patient survival. Clin Cancer Res. 2007, 13 (2 Pt 1): 508-14. 10.1158/1078-0432.CCR-06-1512.
Article
CAS
Google Scholar
Chi YH, Jeang KT: Aneuploidy and cancer. J Cell Biochem. 2007, 102 (3): 531-538. 10.1002/jcb.21484.
Article
CAS
Google Scholar
Weaver BA, Cleveland DW: Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell death. Cancer Cell. 2005, 8 (1): 7-12. 10.1016/j.ccr.2005.06.011.
Article
CAS
Google Scholar
Dey P: Aneuploidy and malignancy: an unsolved equation. J Clin Pathol. 2004, 57 (12): 1245-1249. 10.1136/jcp.2004.018952.
Article
CAS
Google Scholar
Babu JR, Jeganathan KB, Baker DJ, Wu X, Kang-Decker N, van Deursen JM: Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation. J Cell Biol. 2003, 160 (3): 341-353. 10.1083/jcb.200211048.
Article
CAS
Google Scholar
Baker DJ, Jeganathan KB, Cameron JD, Thompson M, Juneja S, Kopecka A, Kumar R, Jenkins RB, de Groen PC, Roche P, van Deursen JM: BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice. Nat Genet. 2004, 36 (7): 744-749. 10.1038/ng1382.
Article
CAS
Google Scholar
Sotillo R, Hernando E, Diaz-Rodriguez E, Teruya-Feldstein J, Cordon-Cardo C, Lowe SW, Benezra R: Mad2 overexpression promotes aneuploidy and tumorigenesis in mice. Cancer Cell. 2007, 11 (1): 9-23. 10.1016/j.ccr.2006.10.019.
Article
CAS
Google Scholar
Shichiri M, Yoshinaga K, Hisatomi H, Sugihara K, Hirata Y: Genetic and epigenetic inactivation of mitotic checkpoint genes hBUB1 and hBUBR1 and their relationship to survival. Cancer Res. 2002, 62 (1): 13-17.
CAS
Google Scholar
Gemma A, Hosoya Y, Seike M, Uematsu K, Kurimoto F, Hibino S, Yoshimura A, Shibuya M, Kudoh S, Emi M: Genomic structure of the human MAD2 gene and mutation analysis in human lung and breast cancers. Lung Cancer. 2001, 32 (3): 289-295. 10.1016/S0169-5002(00)00223-3.
Article
CAS
Google Scholar
Hanks S, Coleman K, Reid S, Plaja A, Firth H, Fitzpatrick D, Kidd A, Mehes K, Nash R, Robin N, Shannon N, Tolmie J, Swansbury J, Irrthum A, Douglas J, Rahman N: Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B. Nat Genet. 2004, 36 (11): 1159-1161. 10.1038/ng1449.
Article
CAS
Google Scholar
Tanudji M, Shoemaker J, L'Italien L, Russell L, Chin G, Schebye XM: Gene silencing of CENP-E by small interfering RNA in HeLa cells leads to missegregation of chromosomes after a mitotic delay. Mol Biol Cell. 2004, 15 (8): 3771-3781. 10.1091/mbc.E03-07-0482.
Article
CAS
Google Scholar
Weaver BA, Silk AD, Montagna C, Verdier-Pinard P, Cleveland DW: Aneuploidy acts both oncogenically and as a tumor suppressor. Cancer Cell. 2007, 11 (1): 25-36. 10.1016/j.ccr.2006.12.003.
Article
CAS
Google Scholar
Liu ST, Hittle JC, Jablonski SA, Campbell MS, Yoda K, Yen TJ: Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis. Nat Cell Biol. 2003, 5 (4): 341-345. 10.1038/ncb953.
Article
CAS
Google Scholar