Figure 2From: 6-Nitro-2-(3-hydroxypropyl)-1H-benz[de]isoquinoline-1,3-dione, a potent antitumor agent, induces cell cycle arrest and apoptosisFlow cytometric assessment of cell cycle of MOLT-4 cells (1 × 106/ml) treated in vitro with compound 1i (10.0 and 16.7 μM) for 24 h or camptothecin (5.0 μM) for 3 hr as reference. Treatment with compound 1i resulted in marked rise in sub-G1, S and G2/M fractions suggesting apoptosis and mitotic delay, respectively.Back to article page