Figure 4From: 6-Nitro-2-(3-hydroxypropyl)-1H-benz[de]isoquinoline-1,3-dione, a potent antitumor agent, induces cell cycle arrest and apoptosisAnalysis of apoptosis induced by compounds in HL-60 cells (5 × 105/well) by flow cytometry using annexin V-FITC and PI. Quadrant analysis of fluorescence intensity of gated cells in FL-1 (annexin V-FITC) and FL-2 (PI) channels was from 10,000 events. A: Stained control; B: Camptothecin (10 μM); C: Cisplatin: (10 μM); D: 1i (10 μM).Back to article page