Figure 7

TEM of control and compound 1i treated (10 μM for 36 h) MOLT-4 cells showing internal ultra structure. The control cells show nucleus (N) with finely dispersed chromatin material and a nucleolus (Nu). The mitochondria with cristae (MC) and ribosomes (R) are seen (Figure A-B). The treatment causes chromatin marginalization (CM), condensation of the nucleus (CN), and vacuolization (V) in the cytoplasm (Figure C-F).