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Table 2 Genotype and allele frequencies for SNP in VEGFR2 loci for patients treated with sorafenib and/or bevacizumab, with or without other agents

From: Hypertension and hand-foot skin reactions related to VEGFR2 genotype and improved clinical outcome following bevacizumab and sorafenib

Allelic variant N Genotype frequencies, N (%) Allelic frequencies
   Wt Het Var p q
VEGFR2 H472Q 170      
   C* 140 82 50 8 0.76 0.24
   AA* 17 12 5 0 0.85 0.15
   Others 13 9 4 0 N/A N/A
VEGFR2 V297I 170      
   C* 140 114 25 1 0.9 0.1
   AA* 17 9 6 2 0.71 0.29
   Others 13 8 5 0 N/A N/A
  1. * Genotyping information was not available for n = 7 Caucasians and n = 1 African American included in subsequent analyses.
  2. C: Caucasians, AA: African-Americans, Others: Hispanic or Asians, Wt: wild-type genotype, Het: heterozygous genotype, Var: homozygous variant genotype, p and q are standard Hardy-Weinberg nomenclature for allele frequencies.