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Figure 2 | Journal of Experimental & Clinical Cancer Research

Figure 2

From: Antitumor activity of selective MEK1/2 inhibitor AZD6244 in combination with PI3K/mTOR inhibitor BEZ235 in gefitinib-resistant NSCLC xenograft models

Figure 2

Synergistic effects of AZD6244-BEZ235 combination therapy on cell viability. NCI-H1993 (A), NCI-H1975 (B) and NCI-H460 (C) cells were treated with AZD6244 alone, BEZ235 alone or AZD6244-BEZ235 in combination for 72 h. Results were analyzed according to the Chou-Talalay method [19]. The combination index (CI) values were calculated by using CalcuSyn software. Mean ± SD, n = 5.

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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