Table 2 Univariate and multivariate analysis of factors associated with overall survival of patients with NSCLC
Clinical variable | Case number | HR (95Â % CI) | P Value |
|---|---|---|---|
Uinvariate analysis | Â | Â | Â |
PAK4 (High vs. Low) | 137/73 | 1.627(1.195–2.215) | 0.002 |
Age (>60 vs. ≤60) | 107/103 | 1.084(0.812–1.446) | 0.584 |
Gender (Male vs. Female) | 136/74 | 1.165(0.864–1.571) | 0.317 |
Histological type (SqCC vs A vs. Other) | 66/124/20 | 1.069(0.832–1.374) | 0.602 |
Distant metastasis (M1 vs. M0) | 34/176 | 5.259(3.512–7.875) | 0.000 |
T factor (T3 + T4 vs. T1 + T2) | 98/112 | 1.090(0.817–1.455) | 0.557 |
Lymph node (N2 + N3 vs. N0 + N1) | 113/97 | 5.349(3.852–7.426) | 0.000 |
Clinical stage (III + IV vs. I + II) | 129/81 | 7.266(5.106–10.339) | 0.000 |
Differentiation (Moderate + high vs. Low) | 95/115 | 1.892(1.412–2.536) | 0.000 |
Multivariate analysis | Â | Â | Â |
PAK4 (How vs. Ligh) | 137/73 | 0.483(0347–0.672) | 0.000 |
Differentiation (Moderate + high vs. Low) | 95/115 | 1.191(0.853–1.663) | 0.305 |
Distant metastasis (M1 vs. M0) | 34/176 | 3.703(2.389–5.740) | 0.000 |
Lymph node (N2 + N3 vs. N0 + N1) | 113/97 | 1.311(0.725–2.372) | 0.371 |
Clinical stage (III + IV vs. I + II) | 129/81 | 5.nn3.069–11.080) | 0.000 |