Open Access

Erratum to: Linc00152 promotes proliferation in gastric cancer through the EGFR-dependent pathway

Contributed equally
Journal of Experimental & Clinical Cancer Research201635:30

https://doi.org/10.1186/s13046-015-0262-2

Received: 24 November 2015

Accepted: 24 November 2015

Published: 9 February 2016

The original article was published in Journal of Experimental & Clinical Cancer Research 2015 34:135

Unfortunately, the original version of this article [1] contained several errors:
  • Table 1 included incorrect EGFR data. The EGFR data shown were obtained from patients with hepatocellular carcinoma rather than gastric cancer as indicated. These data were erroneously included during the drafting of the manuscript. The correct version of Table 1 showing the EGFR data obtained from gastric cancer patients can be found below. In addition, the correct version of Table 1 below does not show the TNM stage data reported in the original Table; as a result, the last sentence in the section “Cytoplasm located Linc00152 was increased in gastric cancer” should read “Here we found significant correlation with tumour size instead of tumour number, differentiation grade or metastasis.”
    Table 1

    Clinical relevance of Linc00152 and EGFR and patients with gastric cancer

     

    Linc00152

     

    EGFR

     

    Feather

    Low

    High

    P value

    Low

    High

    P value

    All cases

    36

    36

     

    36

    36

     

    Age

      

    0.326

      

    0.637

     <60

    11

    15

     

    13

    13

     

     ≥60

    25

    21

     

    23

    23

     

    Gender

      

    0.422

      

    0.061

     Male

    28

    25

     

    23

    30

     

     Female

    8

    11

     

    13

    6

     

    Differentiation grade

      

    0.616

      

    0.616

     Well

    18

    15

     

    15

    18

     

     Moderate

    16

    17

     

    17

    16

     

     Poorly

    2

    4

     

    4

    2

     

    Tumor Size(cm)

      

    0.004

      

    0.016

     ≤5 cm

    20

    8

     

    19

    9

     

     >5 cm

    16

    28

     

    17

    27

     

    Tumor Number

      

    0.772

      

    0.384

     Solitary

    28

    29

     

    30

    27

     

     Multiple

    8

    7

     

    6

    9

     

    Metastasis

      

    0.475

      

    0.812

     Yes

    22

    19

     

    20

    21

     

     No

    14

    17

     

    16

    15

     
  • In Figure 5, panel a was replicated as panel c. The correct Figure 5 can be found below.
    Fig. 5

    Linc00152 highly correlated with EGFR and constitutively activated PI3K/AKT signaling. a Different expression of EGFR mRNA in 72 pairs tissues from gastric cancer patients. b The protein expression level of EGFR in patients with gastric cancer. c, d Patients was divided into Linc00152high and Linc00152low groups based on the median of Linc00152 expression. The mRNA (panel c) and protein expression (panel d) of EGFR were compared in the two groups. e Pearson analysis was performed in calculating the correlation of Linc00152 and EGFR with log-transformed data. f The activation of PI3K/AKT signaling was measured by detecting the p-EGFR, p-PI3K and p-AKT in both cells line and tumors from Xenograft model. Data was presented with mean ± SEM

  • The acknowledgements were given as “This work was supported by the Foundation for the Talents in Six Kinds of Profession of Jiangsu Province (JSGF2015D2914 to J.Z.); Natural Science Foundation of Jiangsu Province (BK20151136 to J.Z.).” Instead of “This work was supported by the Foundation for the Talents in Six Kinds of Profession of Jiangsu Province (WSW-075 to J.Z.); Natural Science Foundation of Jiangsu Province (BK20151136 to J.Z.); National Natural Science Foundation of China (81272712, 81072031 to Z.X.); the National Natural Science Foundation Project of International Cooperation (NSFC-NIH, 812111519 to Z.X.); the Program for Development of Innovative Research Team in the First Affiliated Hospital of NJMU, the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD, JX 10231801 to Z.X.)”.

The correct Table 1 and Fig. 5c, as well as the acknowledgements, can be found below correctly.

Notes

Declarations

Acknowledgements

This work was supported by the Foundation for the Talents in Six Kinds of Profession of Jiangsu Province (WSW-075 to J.Z.); Natural Science Foundation of Jiangsu Province (BK20151136 to J.Z.); National Natural Science Foundation of China (81272712, 81072031 to Z.X.); the National Natural Science Foundation Project of International Cooperation (NSFC-NIH, 812111519 to Z.X.); the Program for Development of Innovative Research Team in the First Affiliated Hospital of NJMU, the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD, JX 10231801 to Z.X.).

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Authors’ Affiliations

(1)
Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University
(2)
Department of Gastrointestinal Surgery, The Affiliated Yixing Hospital of Jiangsu University
(3)
Department of General Surgery, The Affiliated Hospital of Nantong University

Reference

  1. Zhou J, Zhi X, Wang L, Wang W, Li Z, Tang J, et al. Linc00152 promotes proliferation in gastric cancer through the EGFR-dependent pathway. J Exp Clin Cancer Res. 2015;34:135.PubMed CentralView ArticlePubMedGoogle Scholar

Copyright

© Zhou et al. 2016

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