Table 2 ECM as prognostic predictors in OS
From: The role of extracelluar matrix in osteosarcoma progression and metastasis
ECM components | Expression in OS | Prognostic value | References | |
|---|---|---|---|---|
Collagens | CTHRC1 | High | Shorter survival time | [116] |
COL1A1 | High | Shorter survival time | [118] | |
Fibronectin | Â | High | Metastasis, poor response to chemotherapy, and shorter survival time | |
Proteoglycans | CD44 | High | Poor response to chemotherapy | [54] |
Metastasis, recurrence and shorter survival time | ||||