Correction to: YPEL3 suppresses epithelial–mesenchymal transition and metastasis of nasopharyngeal carcinoma cells through the Wnt/β-catenin signaling pathway

Correction to: J Exp Clin Cancer Res 35, 109 (2016)

https://doi.org/10.1186/s13046-016-0384-1

Following publication of the original article [1], the authors identified that mismatched images had been used in Figs. 2, 3 and 6. Specifically, the following panels have been replaced with corrected images created using the raw study data:

• Fig. 2d: effect of YPEL3 on SUNE-1 cells

• Fig. 3b: Si-974 CNE-2 24 h; Si-803 SUNE-1 0 h

• Fig. 3c: Si-838 CNE-2

• Fig. 3d: Si-974 CNE-2 and Si-974 SUNE-1

• Fig. 6c: GAPDH CNE-2 Nu Vector

The corrected figures are given below. The corrections do not affect the conclusions of the article.

Fig. 2

Effects of YPEL3 overexpression on NPC cell migration and invasion in vitro. a Representative western blotting analysis of YPEL3 overexpression in CNE-2 and SUNE-1 cells. GAPDH served as the loading control. b-d Representative images and quantification of the effects of YPEL3 overexpression on the migratory and invasive abilities of CNE-2 and SUNE-1 cells as determined by wound healing (b), Transwell migration (c), and invasion (d) assays. All of the experiments were performed at least three times. Data presented are the mean ± SD; **P < 0.01 compared with control using Student t-test

Fig. 3

Effects of YPEL3 silencing on NPC cell migration and invasion in vitro. a Representative western blotting analysis of YPEL3 silencing in CNE-2 and SUNE-1 cells. GAPDH served as the loading control. b-d Representative images and quantification of the effects of YPEL3 silencing on the migratory and invasive abilities of CNE-2 and SUNE-1 cells as determined by wound healing (b), Transwell migration (c), and invasion assays (d). All of the experiments were performed at least three times. Data presented are the mean ± SD; **P < 0.01 compared with control using Student t-test

Fig. 6

YPEL3 inhibited the Wnt/β-catenin signaling pathway. a Representative western blotting and quantification analysis of GSK-3β, β-catenin, c-MYC, and cyclin D1 expression levels after YPEL3 overexpression. b Representative western blotting and quantification analysis of GSK-3β, β-catenin, c-MYC, and cyclin D1 expression levels after YPEL3 silencing. c YPEL3 inhibited the nuclear (Nu) translocation of β-catenin. Cyto, cytoplasmic. All of the experiments were performed at least three times. Data presented are the mean ± SD; *P < 0.05 and **P < 0.01 compared with control using Student t-test