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Correction to: Dihydroartemisinin inhibits TCTPdependent metastasis in gallbladder cancer
Journal of Experimental & Clinical Cancer Research volume 41, Article number: 124 (2022)
Correction to: J Exp Clin Cancer Res 36, 68 (2017)
Fig. 3A: Incorrect migration assay images originally used for the TCTP-positive cell lines GBC-SD; the correct images are now used, and a scale bar has been added
Fig. 6G: scale bars have been added to the images showing lung metastatic tissues of gallbladder cancer perfused with Indian ink
Fig. S1F: scale bars have been added to the images showing lung metastatic tissues of gallbladder cancer perfused with Indian ink
The corrected figures are given here. The correction does not have any effect on the final conclusions of the paper.
Zhang F, Ma Q, Xu Z, et al. Dihydroartemisinin inhibits TCTP-dependent metastasis in gallbladder cancer. J Exp Clin Cancer Res. 2017;36:68. https://doi.org/10.1186/s13046-017-0531-3.
(A) TCTP expression was evaluated using IHC staining in 73 gallbladder cancer samples obtained from patients. A bar graph summarizes the number of TCTP-positive and -negative tissue samples. (B) Chemical structure of DHA. (C) DHA reduces TCTP expression levels in gallbladder cancer cells. Western blot analysis of TCTP proteins levels in the cell lysates of NOZ cells at 48 h after exposure to DHA (40 μM). β-actin was used as the loading control. (D) TCTP-positive GBC-SD and TCTP-negative EH-GB-2 cells were pre-treated with vehicle or DHA (40 μM) for 2 days and then seeded in transwells for 24 h for the invasion assays. (B) The relative invasion rates are shown in a bar graph. (E) The mice were intravenously injected with TCTP-negative EH-GB-2 cells expressing luciferase to establish a lung metastasis model and then treated with DHA or a vehicle control (PBS) via IP injections every day. The bioluminescence of the cells was monitored every 2 weeks. Proton flux was evaluated using Xenogen IVIS LuminaXR software. The data represent the mean ± SD. **p < 0.001. NS: no significant difference. (F) Representative photos of histological lung metastasis tissues are shown for each group. A bar graph summarizes the number of lung metastases in the DHA-treated and control groups. (G) Kaplan–Meier plots of survival in the mice in the DHA- and control-treated groups.
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Zhang, F., Ma, Q., Xu, Z. et al. Correction to: Dihydroartemisinin inhibits TCTPdependent metastasis in gallbladder cancer. J Exp Clin Cancer Res 41, 124 (2022). https://doi.org/10.1186/s13046-022-02325-1