Fig. 1
From: Aberrant miR-874-3p/leptin/EGFR/c-Myc signaling contributes to nasopharyngeal carcinoma pathogenesis
Leptin is overexpression in nasopharyngeal carcinoma. a The mRNA expression level of leptin was determined in 5 benign nasopharyngeal inflammatory tissues and 20 NPC tissues. b Serum level of leptin in NPC patients and healthy controls were detected by ELISA. c Leptin expression was determined by immunohistochemistry in 50-paired paraffin-embedding NPC tissues and adjacent non-tumor tissues, representative images of pathological tumor stage (T) and lymph node stage (N). d and e Kaplan–Meier survival analysis and log-rank tests indicate that high expression level of leptin was associated with poor OS and DFS in NPC patients