- Correction
- Open Access
- Published:
Correction: Identification of novel COX-2 / CYP19A1 axis involved in the mesothelioma pathogenesis opens new therapeutic opportunities
Journal of Experimental & Clinical Cancer Research volume 42, Article number: 15 (2023)
Correction: J ExpClin Cancer Res 40, 257 (2021)
https://doi.org/10.1186/s13046-021-02050-1
Following publication of the original article [1], author identified an error in Fig. 4a and b, specifically:
-
Figure 4a - Vinculin in MPP89
-
Figure 4b - Tubulin Ist Mes2 and MPP89
AKT and ERK phosphorylation are implicated in the combined action of rofecoxib and exemestane. A Representative experiment out of three independent western blot analyses of pCREB, pERK and pAKT expression in Ist Mes1, Ist Mes2 and MPP89 cells treated with 35μM exemestane (EXE) or 35μM rofecoxib (ROF) or 35μM exemestane and 35μM rofecoxib combination (EXE + ROF) for 30 min. B Representative western blot analyses of COX-2 and CYP19A1 expression in Ist Mes1, Ist Mes2 and MPP89 cells treated with 35μM exemestane (EXE) or 35μM rofecoxib (ROF) or 35μM exemestane and 35μM rofecoxib combination (EXE + ROF) for 24 h. C The graphs represent the mean ± SD of three independent quantifications of protein band intensities normalized to the loading control and then in comparison to the untreated sample (relative band intensity). D The graph represents the mean ± SD of three independent cell survival rates after pre-incubation with MK-2206 and subsequently treated with exemestane (MK-EXE), or rofecoxib (MK + ROF) or exemestane and rofecoxib combination (MK-EXE + ROF) compared to untreated (100 % of cell alive). E Representative western blot analyses of pAKT and pERK expression in Ist Mes2 cells pre-incubated with MK-2206 and after treated with exemestane (MK-EXE), or rofecoxib (MK + ROF) or exemestane and rofecoxib combination (MK-EXE + ROF). F The graph represents the mean ± SD of three independent quantifications of protein band intensities normalized to the loading control. Statistically significant effects (paired Student t test P < 0.05) compared to CNTR *, EXE # or ROF § or MK-CNTR °
The correct figure is presented below:
This correction does not change the result, interpretation, and conclusions of the study. The original article has been corrected.
Reference
Nuvoli B, Antoniani B, Libener R, et al. Identification of novel COX-2 / CYP19A1 axis involved in the mesothelioma pathogenesis opens new therapeutic opportunities. J Exp Clin Cancer Res. 2021;40:257. https://doi.org/10.1186/s13046-021-02050-1.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
About this article
Cite this article
Nuvoli, B., Antoniani, B., Libener, R. et al. Correction: Identification of novel COX-2 / CYP19A1 axis involved in the mesothelioma pathogenesis opens new therapeutic opportunities. J Exp Clin Cancer Res 42, 15 (2023). https://doi.org/10.1186/s13046-022-02539-3
Published:
DOI: https://doi.org/10.1186/s13046-022-02539-3