Fig. 2

Parvimonas micra promotes colorectal cancer in APC^Min/+ mice. A APC^Min/+ mice were administrated with P. micra or PBS for 12 weeks, and fecal collection was performed at the end of gavage. Blood was collected at the midpoint and endpoint of gavage. B Representative images of APC^Min/+ mice colon. C Changes in tumor size, tumor number, and colon length in APC^Min/+ mice. D Representative images of colon pathology. E Serum biochemical assay of APC^Min/+ mice. F Serum cytokine detection in mice at midpoint (6 weeks). G Serum cytokine detection in mice at endpoint (12 weeks). H Linear discriminant analysis effect size analysis of the gut microbiota with 16S rDNA sequencing. Data are expressed as mean ± SD, n = 11