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Correction: Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/ Akt signaling pathway in gastric cancer

The Original Article was published on 26 January 2017

Correction: J Exp Clin Cancer Res 36, 19 (2017)

https://doi.org/10.1186/s13046-016-0487-8

Following the publication of the original article [1], author identified an error in Figure 4, specifically:

  • Figure 4d – migration distance of DOX treated 24h was pasted by using DOX treated 0h

The correct figure is given below.

Fig. 4
figure 1

RES synergized DOX effect on cell proliferation, colony formation and apoptosis and resvered DOX-induced cell migration in SGC7901/ DOX cells. a CCK8 was used to detect the cytotoxicity of DOX, RES or both. SGC7901/DOX cells were left untreated or treated with 0.75 mg/L DOX, 50 mg/L RES or both for 7 days. Each data point represents a mean value of four experiments and the error bars indicate the standard deviation (T test, vs. DOX + RES, *, p < 0.01; **, p < 0.001, n = 4). b Representative pictures of Colony-forming assay and number of cell colonies. After 48 h’ exposure to DOX or RES or both, the colony forming abilitiy of SGC7901/DOX cells was tested. (n = 3, *** p < 0.001; *, p < 0.05). c SGC7901/ DOX cells were treated with 1 mg/L DOX, 1.5 mg/L DOX, 50 mg/L RES, 100 mg/L RES or 0.75 mg/L DOX combined with 50 mg/L RES respectively for 48 h. Annexin V-FITC/PI dual staining apoptosis analysis was performed. The proportions of cells in each quadrant are marked on the figures. d The migration distance was meaured to analysed the migration ability of SGC7901/DOX cells which were left untreated or treated with 1 mg/L DOX, 50 mg/L RES or both for 48 h. The Scale bar represents 100 μm. The migration distance of each group was measured, with 162.89 ± 11.20 μm, 205.11 ± 6.79 μm, 76.34 ± 6.16 μm, 24.36 ± 4.83 μm for control, DOX, RES and DOX + RES group. (n = 4, *** p < 0.001;**p < 0.01). e SGC7901/ DOX cells were left untreated or treated with 1 mg/L DOX, 50 mg/L RES or 1 mg/L DOX simultaneously combined with 50 mg/l RES for 48 h. Then cells were subjected to transwell migration assay. The Scale bar represents 100 μm. The numbers of cells of the control, DOX, RES and DOX + RES groups were 700.40 ± 50.03, 922.00 ± 53.25, 271.60 ± 20.07 and 116.00 ± 6.50 respectively (n = 4, *** p < 0.001;**p < 0.01)

Reference

  1. Xu J, Liu D, Niu H, et al. Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer. J Exp Clin Cancer Res. 2017;36:19. https://doi.org/10.1186/s13046-016-0487-8.

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Correspondence to Qingling Zhang.

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Xu, J., Liu, D., Niu, H. et al. Correction: Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/ Akt signaling pathway in gastric cancer. J Exp Clin Cancer Res 42, 23 (2023). https://doi.org/10.1186/s13046-023-02593-5

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  • DOI: https://doi.org/10.1186/s13046-023-02593-5