Retraction Note: Downregulation of lncRNA ZNF582-AS1 due to DNA hypermethylation promotes clear cell renal cell carcinoma growth and metastasis by regulating the N(6)- methyladenosine modification of MT-RNR1
Journal of Experimental & Clinical Cancer Research volume 42, Article number: 144 (2023)
Retraction Note: J Exp Clin Cancer Res 40, 92 (2021)
The Editor in Chief has retracted this article. After publication, concerns were raised about the following issues:
• OSRC2-ZNF582-AS1 CON panel in Fig. 4c appears to partially overlap with the OSRC2-MT-RNR1 OE panel in Fig. 9g;
• The highlighted sequences in Fig. 6g do not appear to correspond to the positions of the peaks as reported in Fig. 6a;
• The reference number of the ethics permit as reported in the article appears to have been used in multiple other studies dealing with topics and studies that appear to require separate approvals.
The authors provided an explanation which did not address the concerns adequately. The Editor in Chief, therefore, has lost confidence in the integrity of the article’s findings. The corresponding author has stated on behalf of all authors that they disagree to this retraction.
Zhan Y, Chen Z, He S, et al. Long non-coding RNA SOX2OT promotes the stemness phenotype of bladder cancer cells by modulating SOX2. Mol Cancer. 2020;19:25. https://doi.org/10.1186/s12943-020-1143-7.
Li Y, Gong Y, Ning X, et al. Downregulation of CLDN7 due to promoter hypermethylation is associated with human clear cell renal cell carcinoma progression and poor prognosis. J Exp Clin Cancer Res. 2018;37:276. https://doi.org/10.1186/s13046-018-0924-y.
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The online version of the original article can be found at https://doi.org/10.1186/s13046-021-01889-8.
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Yang, W., Zhang, K., Li, L. et al. Retraction Note: Downregulation of lncRNA ZNF582-AS1 due to DNA hypermethylation promotes clear cell renal cell carcinoma growth and metastasis by regulating the N(6)- methyladenosine modification of MT-RNR1. J Exp Clin Cancer Res 42, 144 (2023). https://doi.org/10.1186/s13046-023-02719-9