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  1. To investigate the feasibility of gene therapy in treating Epstein-Barr virus (EBV)-associated cancer by employing the suicide gene, herpes simplex virus thymidine kinase/ganciclovir (HSV-tk/GCV), which uses t...

    Authors: Yang Lifang, Tang Min, Ai Midan and Cao Ya
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:42
  2. To compare computed tomography (CT) with co-registered positron emission tomography-computed tomography (PET-CT) as the basis for delineating gross tumor volume (GTV) in unresectable, locally advanced pancreat...

    Authors: Erkan Topkan, Ali A Yavuz, Mehmet Aydin, Cem Onal, Fuat Yapar and Melek N Yavuz
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:41
  3. β-(1,3)/(1,6) D-glucan, a component of the fungal cell wall, has been shown to stimulate the immune system, enhance hematopoiesis, amplify killing of opsonized tumor cells and increase neutrophil chemotaxis an...

    Authors: Alan B Weitberg
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:40
  4. Patients with hereditary non-poliposys colorectal cancer (HNPCC) have better prognosis than sporadic colorectal cancer (CRC). Aim of our retrospective study was to compare the overall survival between sporadic...

    Authors: Vittoria Stigliano, Daniela Assisi, Maurizio Cosimelli, Raffaele Palmirotta, Diana Giannarelli, Marcella Mottolese, Lupe Sanchez Mete, Raffaello Mancini and Vincenzo Casale
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:39
  5. Lung cancer remains a major health challenge in the world. Survival for patients with stage I disease ranges between 40–70%. This suggests that a significant proportion of patients with stage I NSCLC may actua...

    Authors: Mara Campioni, Vincenzo Ambrogi, Eugenio Pompeo, Gennaro Citro, Mauro Castelli, Enrico P Spugnini, Antonio Gatti, Pierluigi Cardelli, Laura Lorenzon, Alfonso Baldi and Tommaso C Mineo
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:38
  6. The management of hormone-refractory prostate cancer (HRPC) still remains as an important challenge of daily oncology practice. Docetaxel has proved to be a first line treatment choice. All-trans retinoic acid...

    Authors: Yuksel Kucukzeybek, Mustafa K Gul, Ercument Cengiz, Cigdem Erten, Burcak Karaca, Gurbuz Gorumlu, Harika Atmaca, Selim Uzunoglu, Bulent Karabulut, Ulus A Sanli and Ruchan Uslu
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:37
  7. Infected cells recognize viral replication as a DNA damage stress and elicit the host surveillance mechanism to anti-virus infection. Modulation of the activity of tumor suppressor p53 is a key event in the re...

    Authors: Lina Sun, Ge Zhang, Zongfang Li, Tusheng Song, Chen Huang and Lusheng Si
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:35
  8. Reported data indicate that cancer cells have increased rates of glucose metabolism, as determined by 18FDG-PET imaging in patients with malignancies. The results of many studies have demonstrated that the exp...

    Authors: Paola Parente, Antonella Coli, Guido Massi, Antonella Mangoni, Manuela M Fabrizi and Giulio Bigotti
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:34
  9. Follicular dendritic cell (FDC) sarcoma is a rare neoplasm arising in lymph nodes but also in extranodal sites from accessory cells of the immune system that are essential for the function of antigen presentat...

    Authors: Francesco Pisani, Mirella Marino, Steno Sentinelli and Maria Concetta Petti
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:33
  10. Many kinds of Chinese herb had been confirmed to have the character of anti-tumor, clinical reports about anti-tumor effects of Chinese herb had also been found in recent years, but most of the reports were fo...

    Authors: Yun Lu, Chang-Sheng Li and Qian Dong
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:31
  11. To develop a novel therapeutic strategy for human pancreatic cancer using a midkine promoter-based conditionally replicating adenovirus.

    Authors: Eiji Toyoda, Ryuichiro Doi, Kazuhiro Kami, Tomohiko Mori, Daisuke Ito, Masayuki Koizumi, Atsushi Kida, Kazuyuki Nagai, Tatsuo Ito, Toshihiko Masui, Michihiko Wada, Masatoshi Tagawa and Shinji Uemoto
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:30
  12. The detection of sub-clinical breast lesions has increased with screening mammography. Biopsy techniques can offer precision and agility in its execution, as well as patient comfort. This trial compares radiog...

    Authors: Marcelo Moreno, Janete Eunice Wiltgen, Benito Bodanese, Ricardo Ludwig Schmitt, Bianca Gutfilen and Lea Mirian Barbosa da Fonseca
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:29
  13. Deaths after percutaneous ethanol injection (PEI) into hepatocellular carcinoma (HCC) may occur within a few hours to a few days following the procedure because of hemoperitoneum and haemorrhage from oesophage...

    Authors: Enrico M Zardi, Francesco Di Matteo, Daniele Santini, Valentina Uwechie, Pierfilippo Crucitti, Massimiliano Carassiti, Antonio Picardi, Eleonora Perrella, Marco Caricato, Giuseppe Tonini, Roberto Coppola and Antonella Afeltra
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:28
  14. The c-Myc and human telomerase reverse transcriptase gene (hTERT) gene are frequently deregulated and overexpressed in malignancy. hTERT activity is induced by c-Myc and strategies designed to inhibit c-Myc ex...

    Authors: Huang Hao, Yu Nancai, Fu Lei, Wei Xiong, Su Wen, Huang Guofu, Wu yanxia, Huang Hanju, Liu Qian and Xiao Hong
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:27

    The Retraction Note to this article has been published in Journal of Experimental & Clinical Cancer Research 2009 28:101

  15. To evaluate the relationship between Aberrant Crypt Foci (ACF) and tumorigenesis, we observed the sequential development from ACF to tumor in the colon of azoxymethane-exposed wistar rats.

    Authors: Qing Lu, Bo Jiang, Chen Lin and Tao Shan
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:26

    The Erratum to this article has been published in Journal of Experimental & Clinical Cancer Research 2008 27:47

  16. A novel human nuclear receptor interaction protein (NRIP) has recently been discovered by Chen SL et al, which may play a role in enhancing the transcriptional activity of steroid nuclear receptors in prostate...

    Authors: Chih-Ping Han, Ming-Yung Lee, Shu-Ling Tzeng, Chung-Chin Yao, Po-Hui Wang, Ya-Wen Cheng, Show-Li Chen, Teresa S Wu, Yeu-Sheng Tyan and Lai-Fong Kok
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:25
  17. DNA-methyltransferase-3B (DNMT3B), which plays a role in DNA methylation, is usually aberrant expression involved in carcinogenesis. Polymorphisms of the DNMT3B gene may influence DNMT3B activity on DNA methyl...

    Authors: Hong Fan, Feng Zhang, Jiabo Hu, Dongsheng Liu and Zhujiang Zhao
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:24
  18. Heparanase is an endoglycosidase that degrades heparan sulfate, the main polysaccharide constituent of the extracellular matrix (ECM) and basement membrane. Expression of the heparanase gene is associated with...

    Authors: Xin Hong, Feng Jiang, Steven N Kalkanis, Zheng Gang Zhang, Xuepeng Zhang, Xuguang Zheng, Hao Jiang, Tom Mikkelsen and Michael Chopp
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:23
  19. Homeodomain-interacting protein kinase-2 (HIPK2) plays an essential role in restraining tumor progression as it may regulate, by itself or within multiprotein complexes, many proteins (mainly transcription fac...

    Authors: Rosa Puca, Lavinia Nardinocchi and Gabriella D'Orazi
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:22
  20. Cancer and its therapies increase the risk of venous thromboembolism. Compared to patients without cancer, patients with cancer anticoagulated for venous thromboembolism are more likely to develop recurrent th...

    Authors: Elie A Akl, Maddalena Barba, Sandeep Rohilla, Irene Terrenato, Francesca Sperati, Paola Muti and Holger J Schünemann
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:21
  21. The objective was to understand the influence of Survivin plasmid with short hairpin RNA (shRNA) on the cell cycle, invasion, and the silencing effect of Survivin gene in the SW480 cell of colorectal carcinoma.

    Authors: Liu Zhonghong, Lin Lianjie, Zheng Changqing, He Ying, Jin Yu and Lin Yan
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:20
  22. In these years a huge number of human transcripts has been found that do not code for proteins, named non-protein coding RNAs. In most cases, small (miRNAs, snoRNAs) and long RNAs (antisense RNA, dsRNA, and lo...

    Authors: Massimo Mallardo, Palmiro Poltronieri and Oscar Fernando D'Urso
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:19
  23. Several in vitro and in vivo studies have examined the positive and negative effects of retinoids (vitamin A analogs) in premalignant and malignant lesions. Retinoids have been used as chemopreventive and anti...

    Authors: Krisztina Bogos, Ferenc Renyi-Vamos, Gabor Kovacs, Jozsef Tovari and Balazs Dome
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:18
  24. Third world breast cancer is characterized by late presentation, occurrence at relatively young ages and dismal mortality. This poor outcome has encouraged patients to patronize quacks and alternative healers....

    Authors: Stanley NC Anyanwu
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:17
  25. The paper reports the electric, magnetic and electromagnetic fields (emf) measurements carried out in the Regina Elena National Cancer Institute (NCI). Several devices, used in diagnostics and in medical cures, c...

    Authors: Anna Maria Di Nallo, Lidia Strigari, Claudia Giliberti, Angelico Bedini, Raffaele Palomba and Marcello Benassi
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:16
  26. The cellular apoptosis susceptibility (CAS) protein is regarded as a proliferation-associated protein that associates with tumour proliferation as it associates with microtubule and functions in the mitotic sp...

    Authors: Ching-Fong Liao, Shue-Fen Luo, Li-Tzu Li, Chuang-Yu Lin, Ying-Chun Chen and Ming-Chung Jiang
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:15
  27. In nuclear medicine, liquid radiopharmaceuticals for diagnostic or therapeutic purposes are administered to patients by using various types of syringes with different volumes. The activity of each "dose" must ...

    Authors: Lidia Strigari, Marcello Benassi, Pierino De Felice, Marco D'Andrea, Aldo Fazio, Sandro Nocentini, Annelisa d'Angelo and Alessia Ceccatelli
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:14
  28. Multiple Myeloma (MM) is a B cell neoplasm characterized by the clonal proliferation of plasma cells. Skeletal complications are found in up to 80% of myeloma patients at presentation and are major cause of mo...

    Authors: Mehmet Sonmez, Tulin Akagun, Murat Topbas, Umit Cobanoglu, Bircan Sonmez, Mustafa Yilmaz, Ercument Ovali and Serdar Bedii Omay
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:11
  29. Although some clinical and radiological features may predict malignancy presence in intraductal papillary mucinous pancreas neoplasms, preoperative diagnosis remains difficult. In this study we present 7 patie...

    Authors: Gian Luca Baiocchi, Nazario Portolani, Francesco Bertagna, Federico Gheza, Claudio Pizzocaro, Raffaele Giubbini and Stefano M Giulini
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:10
  30. HIV infection is reported to be associated with some malignant lymphomas (ML) so called AIDS-related lymphomas (ARL), with an aggressive behavior and poor prognosis. The ML frequency, pathogenicity, clinical p...

    Authors: Amos R Mwakigonja, Ephata E Kaaya and Edward M Mgaya
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:9
  31. Controversy still exists in the indication and timing of surgical treatment of pulmonary hamartoma (PH). The objective of this study is to summarize the experience and the outcome of the surgical treatment for...

    Authors: Wei Guo, Yun-Ping Zhao, Yao-Guang Jiang, Ru-Wen Wang and Zheng Ma
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:8
  32. We investigated the presence and distribution of the sentinel and the non-sentinel node micrometastases using complete serial sectioning and immunohistochemical staining (IHC), to inspect whether lymph node mi...

    Authors: Kaname Ishii, Shinichi Kinami, Kenichiro Funaki, Hideto Fujita, Itasu Ninomiya, Sachio Fushida, Takashi Fujimura, Genichi Nishimura and Masato Kayahara
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:7
  33. Malignant Mesothelioma is an uncommon and very aggressive tumor that accounts for 1% of all the deaths secondary to malignancy in humans. Interestingly, this neoplasm has been occasionally described in compani...

    Authors: Enrico P Spugnini, Stefania Crispi, Alessandra Scarabello, Giovanni Caruso, Gennaro Citro and Alfonso Baldi
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:6
  34. Five-fluorouracil (FU), mainly associated with leucovorin (L), plays an essential role in chemotherapy of colorectal carcinoma. Moreover, FU ± L has been found to increase the expression of tumor-associated ca...

    Authors: Salvatore P Prete, Mario Turriziani, Maria C Massara, Alessia De Rossi, Pierpaolo Correale, Liana De Vecchis, Francesco Torino, Laura Bonmassar and Angelo Aquino
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:5
  35. To determine the efficacy and safety of heparin (unfractionated heparin (UFH) or low-molecular-weight-heparin (LMWH)) and fondaparinux in improving the survival of patients with cancer.

    Authors: Elie A Akl, Frederiek F van Doormaal, Maddalena Barba, Ganesh Kamath, Seo Young Kim, Saskia Kuipers, Saskia Middeldorp, Victor Yosuico, Heather O Dickinson and Holger J Schünemann
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:4
  36. alpha-Methylacyl-CoA racemase (AMACR), an immunomarker for prostatic adenocarcinoma, has been shown to be expressed in a variety of other neoplasms. This study aims to evaluate immunohistochemical expression o...

    Authors: Wei Li, Philip T Cagle, Rafael C Botero, John J Liang, Zhaoping Zhang and Dongfeng Tan
    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:2

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