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Correction to: Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells

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The original article was published in Journal of Experimental & Clinical Cancer Research 2019 38:184

Correction to: J Exp Clin Cancer Res (2019) 38:184

In the original publication of this article [1], there are two errors.

The first error is in author affiliation information. The corrected author affiliation information is as given hereafter:

Xihong Liu1, Peiyuan Zhao4, Xiujuan Wang1*, Lei Wang1, Yingjun Zhu1, Yadi Song1 and Wei Gao1,2,3*.

1 School of Traditional Chinese Medicine, Beijing Key Lab of TCM Collateral Disease Theory Research, Capital Medical University, Beijing, China.

2 School of Pharmaceutical Sciences, Capital Medical University, Beijing, China.

3 Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China.

4 Basic Discipline of Integrated Chinese and Western Medicine, Henan University of Chinese Medicine, Henan, China.

The second error is in Fig. 8d (panel 2 of Tunel assay, group of 1 mg/kg Cel). The revised Fig. 8 which includes 8d has now been included in this correction.

Fig. 8

Celastrol suppressed the growth of orthotopic xenografts of U251 cells in vivo. a One week after inoculation, MRI scanning of glioma was performed on a 7.0 T MR scanner. b One week after inoculation, H&E staining of tumor tissue was carried out. Scale bars = 50 μm (c) Tumor volumes determined by MRI at 0, 7 and 14 days after inoculation in the 5 different groups. d Tunel assay and immunohistochemical staining of tumor specimens. Scale bars = 50 μm. e The levels of cleaved caspase-3, LC3B, p-JNK, p-Akt and p-mTOR in tumor tissues were detected by western blotting. β-actin was used as an internal control. Data are presented as the Mean ± SD (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001, significantly different compared with the untreated control group

The correct Fig. 8 is given hereafter:

The error: In the initially published version of this article, the picture in the Tunel assay of Cel (1 kg/mg) group are the same with that in Cel (2 kg/mg) group in Fig. 8d.

This error does not affect discussions and conclusions drawn in the article.


  1. 1.

    Liu X, et al. Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells. J Exp Clin Cancer Res. 2019;38:184.

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Correspondence to Xiujuan Wang or Wei Gao.

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