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Correction to: Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells
Journal of Experimental & Clinical Cancer Research volume 38, Article number: 284 (2019)
Correction to: J Exp Clin Cancer Res (2019) 38:184
https://doi.org/10.1186/s13046-019-1173-4
In the original publication of this article [1], there are two errors.
The first error is in author affiliation information. The corrected author affiliation information is as given hereafter:
Xihong Liu1, Peiyuan Zhao4, Xiujuan Wang1*, Lei Wang1, Yingjun Zhu1, Yadi Song1 and Wei Gao1,2,3*.
1 School of Traditional Chinese Medicine, Beijing Key Lab of TCM Collateral Disease Theory Research, Capital Medical University, Beijing, China.
2 School of Pharmaceutical Sciences, Capital Medical University, Beijing, China.
3 Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China.
4 Basic Discipline of Integrated Chinese and Western Medicine, Henan University of Chinese Medicine, Henan, China.
The second error is in Fig. 8d (panel 2 of Tunel assay, group of 1 mg/kg Cel). The revised Fig. 8 which includes 8d has now been included in this correction.
Celastrol suppressed the growth of orthotopic xenografts of U251 cells in vivo. a One week after inoculation, MRI scanning of glioma was performed on a 7.0 T MR scanner. b One week after inoculation, H&E staining of tumor tissue was carried out. Scale bars = 50 μm (c) Tumor volumes determined by MRI at 0, 7 and 14 days after inoculation in the 5 different groups. d Tunel assay and immunohistochemical staining of tumor specimens. Scale bars = 50 μm. e The levels of cleaved caspase-3, LC3B, p-JNK, p-Akt and p-mTOR in tumor tissues were detected by western blotting. β-actin was used as an internal control. Data are presented as the Mean ± SD (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001, significantly different compared with the untreated control group
The correct Fig. 8 is given hereafter:
The error: In the initially published version of this article, the picture in the Tunel assay of Cel (1 kg/mg) group are the same with that in Cel (2 kg/mg) group in Fig. 8d.
This error does not affect discussions and conclusions drawn in the article.
Reference
Liu X, et al. Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells. J Exp Clin Cancer Res. 2019;38:184.
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Liu, X., Zhao, P., Wang, X. et al. Correction to: Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells. J Exp Clin Cancer Res 38, 284 (2019). https://doi.org/10.1186/s13046-019-1285-x
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DOI: https://doi.org/10.1186/s13046-019-1285-x