- Retraction Note
- Open access
- Published:
Retraction Note: Long non-coding RNA MACC1-AS1 promoted pancreatic carcinoma progression through activation of PAX8/ NOTCH1 signaling pathway
Journal of Experimental & Clinical Cancer Research volume 42, Article number: 181 (2023)
Retraction Note: J Exp Clin Cancer Res 38, 344 (2019)
The Editor-in-Chief has retracted this article. After publication, concerns were raised regarding highly similar features in the published images. Specifically:
• Fig. 2f Invasion si-NC and MACC1-AS1 images appear to contain some highly similar areas;
• Fig. 2f Invasion si-MACC1-AS1 and pWPXL images appear to contain an overlapping area;
• Fig. 5a appears to contain some duplicated patterns within each image.
Additionally, Fig. 3a appears highly similar to Fig. 3e in [1], and Fig. 6b β-actin blots appear highly similar to Fig. 2a GAPDH in [2]
Further checks by the publisher have also found that there appear to be duplicated western blot bands and background features in Fig. 3a, signs of erased bands in Fig. 3e, and background irregularities in Fig. 6b and c. In addition, a number of images in Fig. 2f appear highly similar to those in Fig. S1a and c in [2]; Fig. 2g top images appear highly similar to Fig. S2a in [2], and the bottom images share highly similar features with Fig. S2b in [2].
The Editor-in-Chief therefore no longer has confidence in the presented data.
Jiang Jianshuai has stated on behalf of all co-authors that they agree to this retraction.
References
Yang MH, Zhao L, Wang L, et al. Nuclear lncRNA HOXD-AS1 suppresses colorectal carcinoma growth and metastasis via inhibiting HOXD3-induced integrin β3 transcriptional activating and MAPK/AKT signalling. Mol Cancer. 2019;18:31. https://doi.org/10.1186/s12943-019-0955-9.
Zhang Z, Han H, Rong Y, et al. Hypoxia potentiates gemcitabine-induced stemness in pancreatic cancer cells through AKT/Notch1 signaling. J Exp Clin Cancer Res. 2018;37:291. https://doi.org/10.1186/s13046-018-0972-3.
Author information
Authors and Affiliations
Corresponding author
Additional information
Publisher’s Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
The online version of the original article can be found at https://doi.org/10.1186/s13046-019-1332-7.
Rights and permissions
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
About this article
Cite this article
Qi, C., Xiaofeng, C., Dongen, L. et al. Retraction Note: Long non-coding RNA MACC1-AS1 promoted pancreatic carcinoma progression through activation of PAX8/ NOTCH1 signaling pathway. J Exp Clin Cancer Res 42, 181 (2023). https://doi.org/10.1186/s13046-023-02772-4
Published:
DOI: https://doi.org/10.1186/s13046-023-02772-4