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  1. Content type: Research

    Breast cancer is a highly heterogeneous pathology, exhibiting a number of subtypes commonly associated with a poor outcome. Due to their high stability, microRNAs are often regarded as non-invasive cancer biom...

    Authors: Cornelia Braicu, Lajos Raduly, Gabriela Morar-Bolba, Roxana Cojocneanu, Ancuta Jurj, Laura-Ancuta Pop, Valentina Pileczki, Cristina Ciocan, Alin Moldovan, Alexandru Irimie, Alexandru Eniu, Patriciu Achimas-Cadariu, Angelo Paradiso and Ioana Berindan-Neagoe

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:257

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  2. Content type: Research

    Hypoxic tumor microenvironment and maintenance of stemness contribute to drug resistance in breast cancer. However, whether Hypoxia-inducible factor-2α (HIF-2α) in hypoxic tumor microenvironment mediates conve...

    Authors: Yuanyuan Yan, Fangxiao Liu, Li Han, Lin Zhao, Jianjun Chen, Olufunmilayo I Olopade, Miao He and Minjie Wei

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:256

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  3. Content type: Research

    Sodium/hydrogen exchanger 1 (NHE1), encoded by the SLC9A1 gene (SoLute Carrier family 9A1) in humans, is the main H+ efflux mechanism in maintaining alkaline intracellular pH (pHi) and Warburg effects in glioma. ...

    Authors: Xiudong Guan, Lanxin Luo, Gulnaz Begum, Gary Kohanbash, Qingkun Song, Aparna Rao, Nduka Amankulor, Baoshan Sun, Dandan Sun and Wang Jia

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:255

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  4. Content type: Research

    Although tamoxifen is a highly effective drug for treating estrogen receptor–positive (ER+) breast cancer, nearly all patients with metastasis with initially responsive tumors eventually relapse, and die from acq...

    Authors: Yawei Shi, Yang Zhao, Yunjian Zhang, NiJiati AiErken, Nan Shao, Runyi Ye, Ying Lin and Shenming Wang

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:254

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  5. Content type: Research

    The combination of phytochemicals with chemotherapy drugs is an emerging new strategy for cancer therapy to increase antitumor responses.

    Authors: Yang Wang, Xu Deng, Chang Yu, Guosheng Zhao, Jing Zhou, Ge Zhang, Ming Li, Dianming Jiang, Zhengxue Quan and Yuan Zhang

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:251

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  6. Content type: Research

    Actin filament-associated protein 1 antisense RNA 1 (AFAP1-AS1), a long noncoding RNA, is significantly highly expressed and associated with metastasis and poor prognosis in many cancers, including nasopharyngeal...

    Authors: Yu Lian, Fang Xiong, Liting Yang, Hao Bo, Zhaojian Gong, Yumin Wang, Fang Wei, Yanyan Tang, Xiayu Li, Qianjin Liao, Hui Wang, Ming Zhou, Bo Xiang, Xu Wu, Yong Li, Xiaoling Li…

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:253

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  7. Content type: Research

    Temozolomide-perillyl alcohol conjugate (TMZ-POH), a novel Temozolomide (TMZ) analog developed based on the conjugation of TMZ and perillyl alcohol (POH), displayed strong anticancer potency in multiple cancer...

    Authors: Minghui Chang, Xingguo Song, Xinran Geng, Xingwu Wang, Weijun Wang, Thomas C. Chen, Li Xie and Xianrang Song

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:250

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  8. Content type: Research

    There is increasing evidence that liver cancer stem cells (LCSCs) contribute to hepatocellular carcinoma (HCC) initiation and progression. MicroRNA (miRNA) plays a significant functional role by directly regul...

    Authors: Yu-Shui Ma, Zhong-Wei Lv, Fei Yu, Zheng-Yan Chang, Xian-Ling Cong, Xiao-Ming Zhong, Gai-Xia Lu, Jian Zhu and Da Fu

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:252

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  9. Content type: Correction

    In the publication of this article [1], there is an error in Fig. 4b. The Cyto c western blot image in Fig. 4b is misrepresented. This has now been included in this correction. The authors declare that the cor...

    Authors: Rui Yu, Bi-xia Yu, Jun-feng Chen, Xiu-yi Lv, Ze-jun Yan, Yue Cheng and Qi Ma

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:249

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    The original article was published in Journal of Experimental & Clinical Cancer Research 2016 35:40

  10. Content type: Research

    Andrographolide (Andro), a diterpenoid lactone, has been used for treatment of various cancers with less adverse effects. However, the underlying mechanisms regarding its anti-tumor mechanism still remain uncl...

    Authors: Yulin Peng, Yan Wang, Ning Tang, Dongdong Sun, Yulong Lan, Zhenlong Yu, Xinyu Zhao, Lei Feng, Baojing Zhang, Lingling Jin, Fabiao Yu, Xiaochi Ma and Chuanzhu Lv

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:248

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  11. Content type: Research

    The blood-brain barrier (BBB) strongly restricts the entry of anti-glioma drugs into tumor tissues and thus decreases chemotherapy efficacy. Malignant gliomas are highly invasive tumours that use the perivascu...

    Authors: Xue Leng, Jun Ma, Yunhui Liu, Shuyuan Shen, Hai Yu, Jian Zheng, Xiaobai Liu, Libo Liu, Jiajia Chen, Lini Zhao, Xuelei Ruan and Yixue Xue

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:246

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  12. Content type: Research

    The Hedgehog (Hh) signaling pathway plays critical roles in modulating embryogenesis and maintaining tissue homeostasis, with glioma-associated oncogene (GLI) transcription factors being the main mediators. Ab...

    Authors: Dengliang Huang, Yiting Wang, Linlin Xu, Limin Chen, Minzhang Cheng, Wei Shi, Huanting Xiong, Detina Zalli and Shiwen Luo

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:247

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  13. Content type: Research

    Microenvironment cues involved in melanoma progression are largely unknown. Melanoma is highly influenced in its aggressive phenotype by the changes it determinates in its microenvironment, such as pH decrease...

    Authors: Zaira Boussadia, Jessica Lamberti, Fabrizio Mattei, Elisabetta Pizzi, Rossella Puglisi, Cristiana Zanetti, Luca Pasquini, Federica Fratini, Luca Fantozzi, Federica Felicetti, Katia Fecchi, Carla Raggi, Massimo Sanchez, Stefania D’Atri, Alessandra Carè, Massimo Sargiacomo…

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:245

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  14. Content type: Research

    Osteosarcoma is the most common bone cancer. Despite advances, molecular mechanisms associated with osteosarcoma have not been fully understood. Hence, an effective treatment for osteosarcoma has yet to be dev...

    Authors: Dongqing Zuo, Kristen L Shogren, Jie Zang, Donna E Jewison, Brian E Waletzki, Alan L Miller II, Scott H Okuno, Zhengdong Cai, Michael J Yaszemski and Avudaiappan Maran

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:244

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  15. Content type: Research

    Pancreatic cancer is a deadly disease with a very low 5-year patient survival rate of 6–8%. The major challenges of eliminating pancreatic cancer are treatment resistance and stromal barriers to optimal drug a...

    Authors: Xiang Ling, Wenjie Wu, Chuandong Fan, Chao Xu, Jianqun Liao, Laurie J. Rich, Ruea-Yea Huang, Elizabeth A. Repasky, Xinjiang Wang and Fengzhi Li

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:240

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  16. Content type: Research

    Licorice is an herb extensively used for both culinary and medicinal purposes. Various constituents of licorice have been shown to exhibit anti-tumorigenic effect in diverse cancer types. However, majority of ...

    Authors: Changliang Chen, Anitha K. Shenoy, Ravi Padia, Dongdong Fang, Qing Jing, Ping Yang, Shi-Bing Su and Shuang Huang

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:243

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  17. Content type: Research

    Cancer-associated fibroblasts (CAFs) have been widely reported to promote tumor angiogenesis. However, the underlying mechanisms of the proangiogenic switch of CAFs remain poorly understood. This study aims to...

    Authors: Xiaocheng Zhou, Tinglin Yan, Chunming Huang, Zhi Xu, Lin Wang, Erhui Jiang, Hui Wang, Yang Chen, Ke Liu, Zhe Shao and Zhengjun Shang

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:242

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  18. Content type: Research

    Glioblastoma (GBM) is the most common and most malignant primary brain cancer in adults. Despite multimodality treatment, the prognosis is still poor. Therefore, further work is urgently required to discover n...

    Authors: Wei Meng, Baocheng Wang, Weiwei Mao, Jiajia Wang, Yang Zhao, Qifeng Li, Chenran Zhang, Yujie Tang and Jie Ma

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:241

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  19. Content type: Review

    The mechanism by which c-Myc exerts its oncogenic functions is not completely clear and different hypotheses are still under investigation. The knowledge of the capacity of c-Myc to bind exclusively E-box sequ...

    Authors: Matteo Caforio, Cristina Sorino, Stefano Iacovelli, Maurizio Fanciulli, Franco Locatelli and Valentina Folgiero

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:239

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  20. Content type: Research

    Aberrant activation of Wnt/β-catenin signaling pathway is considered to be an important issue in progression and metastasis of various human cancers, especially in colorectal cancer (CRC). MiR-452 could activa...

    Authors: Tingting Li, Xiangyu Jian, Han He, Qiuhua Lai, Xianzheng Li, Danling Deng, Tengfei Liu, Jiehong Zhu, Hongli Jiao, Yaping Ye, Shuyang Wang, Minhui Yang, Lin Zheng, Weijie Zhou and Yanqing Ding

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:238

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  21. Content type: Research

    Long noncoding RNAs (LncRNAs) have been reported to be abnormally expressed in human ovarian cancer and associated with the proliferation and metastasis of cancer cells. The objective of this study was to inve...

    Authors: Huan Yan, Hong Li, Pengyun Li, Xia Li, Jianjian Lin, Linlin Zhu, Maria A. Silva, Xiaofang Wang, Ping Wang and Zhan Zhang

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:237

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  22. Content type: Research

    The L-type amino acid transporter 1 (LAT1/SLC7A5) transports essential amino acids across the plasma membrane. While LAT1 is overexpressed in a variety of human neoplasms, its expression and its role in thyroid c...

    Authors: Pascal Häfliger, Julien Graff, Matthias Rubin, Amandine Stooss, Matthias S. Dettmer, Karl-Heinz Altmann, Jürg Gertsch and Roch-Philippe Charles

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:234

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  23. Content type: Research

    Pancreatic cancer (PC) is the fourth most common cause of cancer death. Combination therapies with classical chemotherapeutic agents improved treatment of advanced PC at the cost of a relevant toxicity, but th...

    Authors: Serena Veschi, Laura De Lellis, Rosalba Florio, Paola Lanuti, Alberto Massucci, Nicola Tinari, Michele De Tursi, Pierluigi di Sebastiano, Marco Marchisio, Clara Natoli and Alessandro Cama

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:236

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  24. Content type: Research

    We previously reported that miR-203 functions as a tumor suppressor in ovarian cancer cells by directly targeting transcription factor Snai2 and inhibiting epithelial to mesenchymal transition (EMT), whereas B...

    Authors: Baojin Wang, Xia Li, Guannan Zhao, Huan Yan, Peixin Dong, Hidemichi Watari, Michelle Sims, Wei Li, Lawrence M Pfeffer, Yuqi Guo and Junming Yue

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:235

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  25. Content type: Research

    Patient-derived xenograft (PDX) tumor model has become a new approach in identifying druggable tumor mutations, screening and evaluating personalized cancer drugs based on the mutated targets.

    Authors: Cheng-Lung Hsu, Kar-Wai Lui, Lang-Ming Chi, Yung-Chia Kuo, Yin-Kai Chao, Chun-Nan Yeh, Li-Yu Lee, Yenlin Huang, Tung-Liang Lin, Mei-Yuan Huang, Yi-Ru Lai, Yuan-Ming Yeh, Hsien-Chi Fan, An-Chi Lin, Yen-Jung Lu, Chia-Hsun Hsieh…

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:233

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  26. Content type: Research

    Cartilage oligomeric matrix protein (COMP) is known to promote fibrosis in skin, lung and liver. Emerging evidence shows that COMP plays critical roles in tumor development, including breast cancer, colon canc...

    Authors: Qing Li, Cong Wang, Yufeng Wang, Liankang Sun, Zhikui Liu, Liang Wang, Tao Song, Yingmin Yao, Qingguang Liu and Kangsheng Tu

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:231

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  27. Content type: Research

    Multidrug resistance (MDR) is often responsible for the failure of chemotherapy treatment, and current strategies for cancer MDR are not adequately satisfying as to their efficacy and safety. In this study, we...

    Authors: Chixiong Huang, Senlin Huang, Hairui Li, Xinzhong Li, Bing Li, Lintao Zhong, Junfeng Wang, Meishen Zou, Xiang He, Hao Zheng, Xiaoyun Si, Wangjun Liao, Yulin Liao, Li Yang and Jianping Bin

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:232

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  28. Content type: Research

    Non-small cell lung cancer (NSCLC) is a leading cause of death worldwide. MicroRNAs (miRNAs) have been indicated as crucial actors in cancer biology. Accumulating evidence suggests that miRNAs can be used as d...

    Authors: Xi He, Si-yuan Chen, Zhao Yang, Jie Zhang, Wei Wang, Mei-yue Liu, Yi Niu, Xiao-mei Wei, Hong-min Li, Wan-ning Hu and Guo-gui Sun

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:230

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  29. Content type: Research

    The sperm-associated antigen 5 (SPAG5) plays a key role in controlling various cellular phenomena, including cell cycle progression and proliferation. However, the role of SPAG5 in hepatocellular carcinoma (HC...

    Authors: Hongliang Liu, Junwen Hu, Ran Wei, Longfei Zhou, Hua Pan, Hongchao Zhu, Mingwen Huang, Jun Luo and Wei Xu

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:229

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  30. Content type: Research

    In this research, we aimed to investigate the biological functions of LIM domain only 3 (LMO3) in hepatocellular carcinoma (HCC) and uncover the underlying molecular mechanism in it.

    Authors: Yang Cheng, Tianlu Hou, Jian Ping, Tianyang Chen and Baobing Yin

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:228

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  31. Content type: Review

    Non-small cell lung cancer (NSCLC) accounts for approximately 85% of lung cancer cases, and it is one of the leading causes of cancer death in both men and women worldwide due to diagnosis in the advanced stag...

    Authors: Hongmei Zheng, Yuting Zhan, Sile Liu, Junmi Lu, Jiadi Luo, Juan Feng and Songqing Fan

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:226

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  32. Content type: Research

    Increasing evidence recognizes that DNA methylation abnormalities play critical roles in cancer development. Our previous genome-wide methylation profile showed that tumor necrosis factor-alpha-induced protein...

    Authors: Xian-Yue Ren, Xin Wen, Ying-Qing Li, Jian Zhang, Qing-Mei He, Xiao-Jing Yang, Xin-Ran Tang, Ya-Qin Wang, Pan-Pan Zhang, Xiao-Zhong Chen, Bin Cheng, Jun Ma and Na Liu

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:227

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  33. Content type: Research

    Tumor recurrence, the chief reason for poor prognosis of glioma, is largely attributed to glioma stem cells (GSCs) and epithelial-mesenchymal transition (EMT). However, the mechanisms among them remain unknown...

    Authors: Jin Zhang, Hongqing Cai, Lixin Sun, Panpan Zhan, Meng Chen, Feng Zhang, Yuliang Ran and Jinghai Wan

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:225

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  34. Content type: Research

    Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal tumor types worldwide. BET inhibitors display anti-tumor activity in pancreatic cancer, however the cells often develop resistance after a long...

    Authors: Bo Wang, Ping Fan, Jingyuan Zhao, Heyu Wu, Xin Jin and Heshui Wu

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:224

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  35. Content type: Review

    Phosphatase and tensin homologue (PTEN) triggers a battery of intracellular signaling pathways, especially PI3K/Akt, playing important roles in the pathogenesis of multiple diseases, such as cancer, neurodevel...

    Authors: Wang Li, Ting Zhang, Lianying Guo and Lin Huang

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:223

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  36. Content type: Research

    Emerging evidence has shown long noncoding RNAs (lncRNAs) exert important roles in colorectal cancer (CRC) tumorigenesis. However, most lncRNAs involved in this process remain undefined and the underlying mole...

    Authors: Jiangtao Yu, Zhiyang Han, Ziquan Sun, Yue Wang, Ming Zheng and Chunfang Song

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:222

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  37. Content type: Research

    Prostate cancer is one of the most common malignancies. Increasing evidence suggested that endothelial cells may contribute to prostate cancer progression and metastasis. Most recently, autophagy has been prop...

    Authors: Ruizhe Zhao, Xiaoyu Bei, Boyu Yang, Xiaohai Wang, Chenyi Jiang, Fei Shi, Xingjie Wang, Yiping Zhu, Yifeng Jing, Bangmin Han, Shujie Xia and Qi Jiang

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:221

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  38. Content type: Research

    Accumulating evidence suggests that cancer stem cells (CSCs) play a critical role in tumor initiation, progression and therapy, and recent studies have indicated that Forkhead box C1 (FOXC1) is strongly associ...

    Authors: Sisi Cao, Zhuo Wang, Xiujuan Gao, Wenjuan He, Yue Cai, Hui Chen and Rong Xu

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:220

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  39. Content type: Research

    ERRα, a constitutive transcription factor that regulates energy metabolism, plays an important role in the progression of various tumours. However, its role in cell survival and proliferation and its implicati...

    Authors: Sheng Zhou, Hongwei Xia, Huanji Xu, Qiulin Tang, Yongzhan Nie, Qi yong Gong and Feng Bi

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:218

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  40. Content type: Research

    Clear cell RCC (ccRCC) accounts for approximately 75% of the renal cancer cases. Surgery treatment seems to be the best efficacious approach for the majority of patients. However, a consistent fraction (30%) o...

    Authors: Simona di Martino, Gabriele De Luca, Ludovica Grassi, Giulia Federici, Romina Alfonsi, Michele Signore, Antonio Addario, Laura De Salvo, Federica Francescangeli, Massimo Sanchez, Valentina Tirelli, Giovanni Muto, Isabella Sperduti, Steno Sentinelli, Manuela Costantini, Luca Pasquini…

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:217

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  41. Content type: Research

    Previous studies report that miR-1-3p, a member of the microRNA-1 family (miR-1), and functions as a tumor suppressor in several different cancers. However, little is known regarding the biological role and in...

    Authors: Sen-Mao Li, Huan-Lei Wu, Xiao Yu, Kun Tang, Shao-Gang Wang, Zhang-Qun Ye and Jia Hu

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:219

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  42. Content type: Research

    Plant homeodomain finger protein 8 (PHF8) serves an activator of epithelial-mesenchymal transition (EMT) and is implicated in various tumors. However, little is known about PHF8 roles in hepatocellular carcino...

    Authors: Wuhua Zhou, Li Gong, Qinchuan Wu, Chunyang Xing, Bajin Wei, Tianchi Chen, Yuan Zhou, Shengyong Yin, Bin Jiang, Haiyang Xie, Lin Zhou and Shusen Zheng

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:215

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    The Correction to this article has been published in Journal of Experimental & Clinical Cancer Research 2018 37:270

  43. Content type: Research

    Hypoxia-inducible factor 1α (HIF-1α) is essential in hepatocellular carcinoma (HCC) glycolysis and progression. Yes-associated protein (YAP) is a powerful regulator and is overexpressed in many cancers, includ...

    Authors: Xiaodong Zhang, Yan Li, Yingbo Ma, Liang Yang, Tao Wang, Xin Meng, Zhihong Zong, Xun Sun, Xiangdong Hua and Hangyu Li

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:216

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  44. Content type: Review

    Hepatocellular carcinoma (HCC) is a highly malignant disease with a poor prognosis and high mortality due to a low early diagnosis rate, resistance to systemic treatments and progression to late-stage liver di...

    Authors: Jie Li, Xu Han, Xiaona Yu, Zongzhen Xu, Guangsheng Yang, Bingqi Liu and Peng Xiu

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:213

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  45. Content type: Research

    Although metabolism is profoundly altered in human liver cancer, the extent to which experimental models, e.g. cell lines, mimic those alterations is unresolved. Here, we aimed to determine the resemblance of ...

    Authors: Zeribe C. Nwosu, Nadia Battello, Melanie Rothley, Weronika Piorońska, Barbara Sitek, Matthias P. Ebert, Ute Hofmann, Jonathan Sleeman, Stefan Wölfl, Christoph Meyer, Dominik A. Megger and Steven Dooley

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:211

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    The Correction to this article has been published in Journal of Experimental & Clinical Cancer Research 2018 37:267

  46. Content type: Research

    The development of potent non-toxic chemotherapeutic drugs against castration resistant prostate cancer (CRPC) remains a major challenge. Corosolic acid (CA), a natural triterpenoid, has anti-cancer activity w...

    Authors: Bo Ma, Hang Zhang, Yu Wang, Ang Zhao, Zhiming Zhu, Xiaowen Bao, Yang Sun, Lin Li and Qi Zhang

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:210

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  47. Content type: Research

    Misregulation of the p53-mdm2 loop function is a major mechanism to promote hepatocellular carcinoma (HCC). RBM38, a member of the RNA recognition motif (RRM) family of RNA binding proteins (RBPs), plays a fun...

    Authors: Jiazhou Ye, Rong Liang, Tao Bai, Yan Lin, Rongyun Mai, Meng Wei, Xinqin Ye, Lequn Li and Feixiang Wu

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:212

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  48. Content type: Research

    Emerging evidences have indicated that long noncoding RNAs (lncRNAs) play essential roles in the development and progression of cancers. Dysregulation of lncRNA MIR31HG has recently been reported in several ty...

    Authors: Shaoying Yan, Zhenrong Tang, Ke Chen, Yuyang Liu, Gangfeng Yu, Qiuxu Chen, Hao Dang, Fengjiao Chen, Jiaji Ling, Liying Zhu, Ailong Huang and Hua Tang

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:214

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  49. Content type: Research

    Enzymatically inactive chitinase-like protein CHI3L1 drives inflammatory response and promotes tumor progression. However, its role in gastric cancer (GC) tumorigenesis and metastasis has not yet been fully el...

    Authors: Biao Geng, Jinshun Pan, Ting Zhao, Jie Ji, Chen Zhang, Ying Che, Jing Yang, Hui Shi, Juan Li, Hong Zhou, Xianmin Mu, Che Xu, Chao Wang, Yue Xu, Zheng Liu, Hao Wen…

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:208

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  50. Content type: Research

    Angiogenesis has become an attractive target for cancer therapy. However, despite the initial success of anti-VEGF (Vascular endothelial growth factor) therapies, the overall survival appears only modestly imp...

    Authors: Marie Ouarné, Claire Bouvard, Gabriela Boneva, Christine Mallet, Johnny Ribeiro, Agnès Desroches-Castan, Emmanuelle Soleilhac, Emmanuelle Tillet, Olivier Peyruchaud and Sabine Bailly

    Citation: Journal of Experimental & Clinical Cancer Research 2018 37:209

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