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  1. Pancreatic ductal adenocarcinoma (PDAC) is an extremely lethal malignancy, with an average 5-year survival rate of 9% (Siegel RL, Miller KD, Jemal A. Ca Cancer J Clin. 2019;69(1):7-34). The steady increase in ...

    Authors: Yiqi Yu, Gang Yang, Hua Huang, Ziyao Fu, Zhe Cao, Lianfang Zheng, Lei You and Taiping Zhang

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:8

    Content type: Review

    Published on:

  2. Gastric cancer (GC) is one of the most common malignant tumors worldwide. Currently, the overall survival rate of GC is still unsatisfactory despite progress in diagnosis and treatment. Therefore, studying the...

    Authors: Jiacheng Cao, Xing Zhang, Penghui Xu, Haixiao Wang, Sen Wang, Lu Zhang, Zheng Li, Li Xie, Guangli Sun, Yiwen Xia, Jialun Lv, Jing Yang and Zekuan Xu

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:6

    Content type: Research

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  3. Choline kinase-α (ChoKα/CHKA) overexpression and hyper-activation sustain altered choline metabolism conferring the cholinic phenotype to epithelial ovarian cancer (OC), the most lethal gynecological tumor. We pr...

    Authors: Andrea Rizzo, Alessandro Satta, Giulia Garrone, Adalberto Cavalleri, Alessandra Napoli, Francesco Raspagliesi, Mariangela Figini, Loris De Cecco, Egidio Iorio, Antonella Tomassetti, Delia Mezzanzanica and Marina Bagnoli

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:5

    Content type: Research

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  4. Progranulin (PGRN), as a multifunctional growth factor, is overexpressed in multiple tumors, but the role of PGRN on tumor immunity is still unclear. Here, we studied the effect of PGRN on breast cancer tumor ...

    Authors: Wenli Fang, Ting Zhou, He Shi, Mengli Yao, Dian Zhang, Husun Qian, Qian Zeng, Yange Wang, Fangfang Jin, Chengsen Chai and Tingmei Chen

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:4

    Content type: Research

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  5. Early studies indicated that ASC-J9®, an androgen receptor (AR) degradation enhancer, could suppress the prostate cancer (PCa) progression. Here we found ASC-J9® could also suppress the PCa progression via an ...

    Authors: Hao Tian, Fu-ju Chou, Jing Tian, Yong Zhang, Bosen You, Chi-Ping Huang, Shuyuan Yeh, Yuanjie Niu and Chawnshang Chang

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:3

    Content type: Research

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  6. Both E2F transcription factor and cyclin-dependent kinases (CDKs), which increase or decrease E2F activity by phosphorylating E2F or its partner, are involved in the control of cell proliferation, and some cir...

    Authors: Jin-Chun Qi, Zhan Yang, Tao Lin, Long Ma, Ya-Xuan Wang, Yong Zhang, Chun-Cheng Gao, Kai-Long Liu, Wei Li, An-Ning Zhao, Bei Shi, Hong Zhang, Dan-Dan Wang, Xiao-Lu Wang, Jin-Kun Wen and Chang-Bao Qu

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:2

    Content type: Research

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  7. Hepatitis B virus (HBV) infection is a crucial risk factor for hepatocellular carcinoma (HCC). However, its underlying mechanism remains understudied.

    Authors: Wenbiao Chen, Jingjing Jiang, Lan Gong, Zheyue Shu, Dairong Xiang, Xujun Zhang, Kefan Bi and Hongyan Diao

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:1

    Content type: Research

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  8. Nerve-cancer interactions are increasingly recognized to be of paramount importance for the emergence and progression of pancreatic cancer (PCa). Here, we investigated the role of indirect cholinergic activation ...

    Authors: Paulo L. Pfitzinger, Laura Fangmann, Kun Wang, Elke Demir, Engin Gürlevik, Bettina Fleischmann-Mundt, Jennifer Brooks, Jan G. D’Haese, Steffen Teller, Andreas Hecker, Moritz Jesinghaus, Carsten Jäger, Lei Ren, Rouzanna Istvanffy, Florian Kühnel, Helmut Friess…

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:289

    Content type: Research

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  9. Growing evidence supports the pivotal role of long non-coding RNAs (lncRNAs) in the regulation of cancer development and progression. Their expression patterns and biological function in muscle invasive bladde...

    Authors: Sheng Wu, Katja Nitschke, Thomas Stefan Worst, Alexander Fierek, Cleo-Aron Weis, Markus Eckstein, Stefan Porubsky, Maximilian Kriegmair and Philipp Erben

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:288

    Content type: Research

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  10. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Cristina Alexandra Ciocan-Cartita, Ancuta Jurj, Oana Zanoaga, Roxana Cojocneanu, Laura-Ancuta Pop, Alin Moldovan, Cristian Moldovan, Alina Andreea Zimta, Lajos Raduly, Cecilia Pop-Bica, Mihail Buse, Liviuta Budisan, Piroska Virag, Alexandru Irimie, Sandra Martha Gomes Dias, Ioana Berindan-Neagoe…

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:287

    Content type: Correction

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    The original article was published in Journal of Experimental & Clinical Cancer Research 2020 39:241

  11. Increasing evidence has revealed the close link between mitochondrial dynamic dysfunction and cancer. MIEF2 (mitochondrial elongation factor 2) is mitochondrial outer membrane protein that functions in the reg...

    Authors: Shuhua Zhao, Xiaohong Zhang, Yuan Shi, Lu Cheng, Tingting Song, Bing Wu, Jia Li and Hong Yang

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:286

    Content type: Research

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  12. Colorectal cancer (CRC) harboring BRAFV600E mutation exhibits low response to conventional therapy and poorest prognosis. Due to the emerging correlation between gut microbiota and CRC carcinogenesis, we investig...

    Authors: Nadia Trivieri, Riccardo Pracella, Maria Grazia Cariglia, Concetta Panebianco, Paola Parrella, Alberto Visioli, Fabrizio Giani, Amata Amy Soriano, Chiara Barile, Giuseppe Canistro, Tiziana Pia Latiano, Lucia Dimitri, Francesca Bazzocchi, Dario Cassano, Angelo L. Vescovi, Valerio Pazienza…

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:285

    Content type: Research

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  13. The enthusiasm for immune checkpoint inhibitors (ICIs), an efficient tumor treatment model different from traditional treatment, is based on their unprecedented antitumor effect, but the occurrence of immune-r...

    Authors: Xiao-Hui Jia, Lu-Ying Geng, Pan-Pan Jiang, Hong Xu, Ke-Jun Nan, Yu Yao, Li-Li Jiang, Hong Sun, Tian-Jie Qin and Hui Guo

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:284

    Content type: Review

    Published on:

  14. Circular RNAs (circRNAs), important members of the noncoding RNA family, have been recently revealed to play a role in the pathogenic progression of diseases, particularly in the malignant progression of cance...

    Authors: Hanchen Xu, Yujing Liu, Peiqiu Cheng, Chunyan Wang, Yang Liu, Wenjun Zhou, Yangxian Xu and Guang Ji

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:283

    Content type: Research

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  15. Androgen deprivation therapy (ADT) is the backbone of therapy for advanced prostate cancer (PCa). Despite the good initial response, castration resistance and metastatic progression will inevitably occur. Canc...

    Authors: Yu Zhang, Jing Zhao, Mao Ding, Yiming Su, Di Cui, Chenyi Jiang, Sheng Zhao, Gaozhen Jia, Xiaohai Wang, Yuan Ruan, Yifeng Jing, Shujie Xia and Bangmin Han

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:282

    Content type: Research

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  16. Circular RNAs (circRNAs) have been reported to play key roles in the development of various cancers. However, the biological functions and clinical significance of most circRNAs are still elusive. The purpose ...

    Authors: Yanan Zhang, Lu Zhao, Shizhou Yang, Yixuan Cen, Tingjia Zhu, Lingfang Wang, Lili Xia, Yuwan Liu, Jian Zou, Junfen Xu, Yang Li, Xiaodong Cheng, Weiguo Lu, Xinyu Wang and Xing Xie

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:281

    Content type: Research

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  17. Accumulating evidences have shown that circular RNAs (circRNAs) play important roles in regulating the pathogenesis of cancer. However, the role of circRNAs in gastric cancer (GC) remains largely unclear.

    Authors: Qiuling Niu, Zhijie Dong, Min Liang, Yuanwei Luo, Hai Lin, Mingzhen Lin, Xiu Zhong, Wenxia Yao, Jinsheng Weng and Xinke Zhou

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:280

    Content type: Research

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  18. HER2-targeting agents have dramatically changed the therapeutic landscape of HER2+ advanced breast cancer (ABC). Within a short time frame, the rapid introduction of new therapeutics has led to the approval of...

    Authors: Giulia Bon, Laura Pizzuti, Valentina Laquintana, Rossella Loria, Manuela Porru, Caterina Marchiò, Eriseld Krasniqi, Maddalena Barba, Marcello Maugeri-Saccà, Teresa Gamucci, Rossana Berardi, Lorenzo Livi, Corrado Ficorella, Clara Natoli, Enrico Cortesi, Daniele Generali…

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:279

    Content type: Research

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  19. Induction therapy for acute myeloid leukemia (AML) is an anthracycline-based chemotherapy regimen. However, many patients experience a relapse or exhibit refractory disease (R/R). There is an urgent need for m...

    Authors: Hao Wang, Yu-chen Liu, Cheng-ying Zhu, Fei Yan, Meng-zhen Wang, Xiao-su Chen, Xiao-kai Wang, Bao-xu Pang, Yong-hui Li, Dai-hong Liu, Chun-ji Gao, Shu-jun Liu and Li-ping Dou

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:278

    Content type: Research

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  20. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Fei Teng, Ju-Xiang Zhang, Qi-Meng Chang, Xu-Bo Wu, Wei-Guo Tang, Jian-Fa Wang, Jin-Feng Feng, Zi-Ping Zhang and Zhi-Qiu Hu

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:277

    Content type: Correction

    Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2020 39:235

  21. Platinum-based anticancer drugs have been at the frontline of cancer therapy for the last 40 years, and are used in more than half of all treatments for different cancer types. However, they are not universall...

    Authors: Alice Domenichini, Ilaria Casari, Peter V. Simpson, Nima Maheshkumar Desai, Lingfeng Chen, Christopher Dustin, Jeanne S. Edmands, Albert van der Vliet, Moosa Mohammadi, Massimiliano Massi and Marco Falasca

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:276

    Content type: Research

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  22. Alternative splicing (AS) is a pervasive molecular process generating multiple protein isoforms, from a single gene. It plays fundamental roles during development, differentiation and maintenance of tissue hom...

    Authors: Anna Di Matteo, Elisa Belloni, Davide Pradella, Ambra Cappelletto, Nina Volf, Serena Zacchigna and Claudia Ghigna

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:275

    Content type: Review

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  23. The identification of novel targets for recovering sorafenib resistance is pivotal for Hepatocellular carcinoma (HCC) patients. Mitophagy is the programmed degradation of mitochondria, and is likely involved i...

    Authors: Hong Wu, Tao Wang, Yiqiang Liu, Xin Li, Senlin Xu, Changtao Wu, Hongbo Zou, Mianfu Cao, Guoxiang Jin, Jinyi Lang, Bin Wang, Baohua Liu, Xiaolin Luo and Chuan Xu

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:274

    Content type: Research

    Published on:

  24. MUC18 is a glycoprotein highly expressed on the surface of melanoma and other cancers which promotes tumor progression and metastasis. However, its mechanism of action and suitability as a therapeutic target a...

    Authors: Runhua Feng, Yuling Wang, Vijaya Ramachandran, Qinhong Ma, Matthew M. May, Ming Li, Joe X. Zhou, Xiang Xu, Kejing Xu, Shenying Fang, Weiya Xia, Dawen Sui, Huey Liu, Xiaolian Gao, Victor Prieto, Stephen C. Blacklow…

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:273

    Content type: Research

    Published on:

  25. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Anquan Shang, Weiwei Wang, Chenzheng Gu, Chen Chen, Bingjie Zeng, Yibao Yang, Ping Ji, Junjun Sun, Junlu Wu, Wenying Lu, Zujun Sun and Dong Li

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:272

    Content type: Correction

    Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2019 38:411

  26. An increasing number of studies have shown that long noncoding RNAs (lncRNAs) play important roles in diverse cellular processes, including proliferation, apoptosis, migration, invasion, chromatin remodeling, ...

    Authors: Le Zhang, Cuixia Li and Xiulan Su

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:271

    Content type: Review

    Published on:

  27. Emerging evidence suggests that epithelial mesenchymal transition (EMT) and epigenetic mechanisms promote metastasis. Histone deacetylases (HDACs) and noncoding RNAs (ncRNAs) are important epigenetic regulators. ...

    Authors: Xue-ting Hu, Wei Xing, Rong-sen Zhao, Yan Tan, Xiao-feng Wu, Luo-quan Ao, Zhan Li, Meng-wei Yao, Mu Yuan, Wei Guo, Shang-ze Li, Jian Yu, Xiang Ao and Xiang Xu

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:270

    Content type: Research

    Published on:

  28. Renal cell carcinoma (RCC) is a common urological cancer. circular RNAs (circRNAs) is involved in the development of various types of cancers. However, the roles and underlying mechanisms of circRNAs in RCC ar...

    Authors: Jiafu Feng, Yongcan Guo, Yuanmeng Li, Jiawei Zeng, Yaodong Wang, Yuwei Yang, Gang Xie and Qian Feng

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:269

    Content type: Research

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  29. Emerging studies revealed that cancer stem cells (CSCs) possessed peculiar metabolic properties, which however remained largely unknown in hepatocellular carcinoma (HCC). Genetic silencing of liver-abundant mi...

    Authors: Yuanzhuo Gu, Fubo Ji, Niya Liu, Yongzhi Zhao, Xiyang Wei, Shiyuan Hu, Wei Jia, Xin Wei Wang, Anuradha Budhu, Juling Ji, Bin Zhao, Stephanie Roessler, Xin Zheng and Junfang Ji

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:268

    Content type: Research

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  30. Pancreatic cancer is one of the most malignant tumors worldwide, and pancreatic ductal adenocarcinoma is the most common type. In pancreatic cancer, glycolysis is the primary way energy is produced to maintain...

    Authors: Lidong Cao, Jiacheng Wu, Xianzhi Qu, Jiyao Sheng, Mengying Cui, Shui Liu, Xu Huang, Yien Xiang, Bingjin Li, Xuewen Zhang and Ranji Cui

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:267

    Content type: Review

    Published on:

  31. Tumor angiogenesis is regarded as a rational anti-cancer target. The efficacy and indications of anti-angiogenic therapies in clinical practice, however, are relatively limited. Therefore, there still exists a...

    Authors: Lili Quan, Ryuichi Ohgaki, Saori Hara, Suguru Okuda, Ling Wei, Hiroki Okanishi, Shushi Nagamori, Hitoshi Endou and Yoshikatsu Kanai

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:266

    Content type: Research

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  32. In spite of great progress in the surgical and clinical management, until now no significant improvement in overall survival of High-Grade Serous Ovarian Cancer (HGSOC) patients has been achieved. Important as...

    Authors: Marta De Donato, Gabriele Babini, Simona Mozzetti, Marianna Buttarelli, Alessandra Ciucci, Gloria Arduini, Maria Cristina De Rosa, Giovanni Scambia and Daniela Gallo

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:265

    Content type: Research

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  33. It is known that the transcription factor zinc finger protein 703 (ZNF703) plays an important role in physiological functions and the occurrence and development of various tumors. However, the role and mechani...

    Authors: Shuang Wang, Caixia Wang, Yuexin Hu, Xiao Li, Shan Jin, Ouxuan Liu, Rui Gou, Yuan Zhuang, Qian Guo, Xin Nie, Liancheng Zhu, Juanjuan Liu and Bei Lin

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:264

    Content type: Research

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  34. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Zihang Xu, Fei Zhang, Chao Bai, Chao Yao, Hairong Zhong, Chunpu Zou and Xiao Chen

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:263

    Content type: Correction

    Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2017 36:124

  35. Recent genomic analyses revealed that druggable molecule targets were only detectable in approximately 6% of patients with nasopharyngeal carcinoma (NPC). However, a dependency on dysregulated CDK4/6–cyclinD1 ...

    Authors: Zhichao Xue, Vivian Wai Yan Lui, Yongshu Li, Lin Jia, Chanping You, Xin Li, Wenying Piao, Hui Yuan, Pek Lan Khong, Kwok Wai Lo, Lydia Wai Ting Cheung, Victor Ho Fan Lee, Anne Wing Mui Lee, Sai Wah Tsao and Chi Man Tsang

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:262

    Content type: Research

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  36. Diffuse intrinsic pontine glioma (DIPG) is an aggressive pediatric brainstem tumor. Most DIPGs harbor a histone H3 mutation, which alters histone post-translational modification (PTM) states and transcription....

    Authors: Shejuan An, Jeannie M. Camarillo, Tina Yi-Ting Huang, Daphne Li, Juliette A. Morris, Madeline A. Zoltek, Jin Qi, Mandana Behbahani, Madhuri Kambhampati, Neil L. Kelleher, Javad Nazarian, Paul M. Thomas and Amanda M. Saratsis

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:261

    Content type: Research

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  37. The E6 oncoproteins of human papillomavirus (HPV) 16/18 are the critical drivers of cervical cancer (CC) progression. Extracellular vesicles (EVs) are emerging as critical mediators of cancer-tumor microenviro...

    Authors: Jun-Jun Qiu, Shu-Gen Sun, Xiao-Yan Tang, Ying-Ying Lin and Ke-Qin Hua

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:260

    Content type: Research

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  38. Emerging evidence suggests that circular RNAs play critical roles in disease development especially in cancers. Previous genome-wide RNA-seq studies found that a circular RNA derived from SOD2 gene was highly ...

    Authors: Zhongwei Zhao, Jingjing Song, Bufu Tang, Shiji Fang, Dengke Zhang, Liyun Zheng, Fazong Wu, Yang Gao, Chunmiao Chen, Xianghua Hu, Qiaoyou Weng, Yang Yang, Jianfei Tu and Jiansong Ji

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:259

    Content type: Research

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  39. Dendritic cells (DCs) secrete vast quantities of exosomes termed as dexosomes. Dexosomes are symmetric nanoscale heat-stable vesicles that consist of a lipid bilayer displaying a characteristic series of lipid...

    Authors: Sepideh Nikfarjam, Jafar Rezaie, Fatah Kashanchi and Reza Jafari

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:258

    Content type: Review

    Published on:

  40. Gliomas, especially glioblastomas, represent one of the most aggressive and difficult-to-treat human brain tumors. In the last few decades, clinical immunotherapy has been developed and has provided exceptiona...

    Authors: Yuanliang Yan, Shuangshuang Zeng, Zhicheng Gong and Zhijie Xu

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:257

    Content type: Review

    Published on:

  41. Accumulating evidence suggests that radiation treatment causes an adaptive response of lung adenocarcinoma (LUAD), which in turn attenuates the lethal effect of the irradiation. Previous microarray assays mani...

    Authors: Chun-cheng Hao, Cui-yang Xu, Xin-yu Zhao, Jia-ning Luo, Gang Wang, Li-hong Zhao, Xiaofeng Ge and Xiao-feng Ge

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:256

    Content type: Research

    Published on:

  42. Dysregulation of cell cycle progression is a common feature of human cancer cells; however, its mechanism remains unclear. This study aims to clarify the role and the underlying mechanisms of Roquin1 in cell c...

    Authors: Wenbao Lu, Meicen Zhou, Bing Wang, Xueting Liu and Bingwei Li

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:255

    Content type: Research

    Published on:

  43. Osteosarcoma is generally reported among younger individuals and has a very poor prognosis, particularly for the development of metastasis. However, more effective metastatic biomarkers and therapeutic methods...

    Authors: Ju-Fang Liu, Po-Chun Chen, Tsung-Ming Chang and Chun-Han Hou

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:254

    Content type: Research

    Published on:

  44. Sphingosine-1-phosphate receptor 2 (S1PR2) mediates pleiotropic functions encompassing cell proliferation, survival, and migration, which become collectively de-regulated in cancer. Information on whether S1PR2 p...

    Authors: Luciana Petti, Giulia Rizzo, Federica Rubbino, Sudharshan Elangovan, Piergiuseppe Colombo, Silvia Restelli, Andrea Piontini, Vincenzo Arena, Michele Carvello, Barbara Romano, Tommaso Cavalleri, Achille Anselmo, Federica Ungaro, Silvia D’Alessio, Antonino Spinelli, Sanja Stifter…

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:253

    Content type: Research

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  45. Circular RNA (circRNA) is emerging as an important player in human diseases, especially cancer. In our previous study, we identified a series of deregulated circRNAs in hepatocellular carcinoma (HCC) by perfor...

    Authors: Suofeng Sun, Jing Gao, Shen Zhou, Yuan Li, Yu Wang, Li Jin, Jian Li, Bowei Liu, Bingyong Zhang, Shuangyin Han, Hui Ding and Xiuling Li

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:252

    Content type: Research

    Published on:

  46. Wingless and Int-related protein (Wnt) ligands are aberrantly expressed in patients with colorectal cancer (CRC). However, the aberrant level of Wnt ligands in serum have not been explored. Here, we aimed to i...

    Authors: Dongmei Yang, Qing Li, Renduo Shang, Liwen Yao, Lianlian Wu, Mengjiao Zhang, Lihui Zhang, Ming Xu, Zihua Lu, Jie Zhou, Li Huang, Xiaodong Huang, Du Cheng, Yanning Yang and Honggang Yu

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:251

    Content type: Research

    Published on:

  47. Glycolysis plays an essential role in the growth and metastasis of solid cancer and has received increasing attention in recent years. However, the complex regulatory mechanisms of tumour glycolysis remain elu...

    Authors: Zhenqiang Sun, Qiuge Zhang, Weitang Yuan, Xiaoli Li, Chen Chen, Yaxin Guo, Bo Shao, Qin Dang, Quanbo Zhou, Qisan Wang, Guixian Wang, Jinbo Liu and Quancheng Kan

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:250

    Content type: Research

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  48. Accumulating evidence showed that regulating tumor microenvironment plays a vital role in improving antitumor efficiency. Programmed Death Ligand 1 (PD-L1) is expressed in many cancer cell types, while its bin...

    Authors: Ze-Bo Jiang, Ju-Min Huang, Ya-Jia Xie, Yi- Zhong Zhang, Chan Chang, Huan-Ling Lai, Wenjun Wang, Xiao-Jun Yao, Xing-Xing Fan, Qi-Biao Wu, Chun Xie, Mei-Fang Wang and Elaine Lai-Han Leung

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:249

    Content type: Research

    Published on:

  49. The mechanism of histone deacetylase 3 (HDAC3) in colorectal cancer (CRC) has already been discussed. However, the feedback loop of HDAC3/microRNA (miR)-296-3p and transforming growth factor β-induced factor 1...

    Authors: Jinxiao Li, Man Hu, Na Liu, Huarong Li, Zhaomin Yu, Qian Yan, Minfeng Zhou, Yayuan Wang, Yanjuan Song, Guangtao Pan, Fengxia Liang and Rui Chen

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:248

    Content type: Research

    Published on:

  50. Cisplatin (CDDP) is the first-line chemotherapy for gastric cancer (GC). The poor prognosis of GC patients is partially due to the development of CDDP resistance. Circular RNAs (circRNAs) are a subclass of non...

    Authors: Guangli Sun, Zheng Li, Zhongyuan He, Weizhi Wang, Sen Wang, Xing Zhang, Jiacheng Cao, Penghui Xu, Haixiao Wang, Xiaoxu Huang, Yiwen Xia, Jialun Lv, Zhe Xuan, Tianlu Jiang, Lang Fang, Jing Yang…

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:246

    Content type: Research

    Published on:

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