Kitamura K, Stockert E, Garin-Chesa P, Welt S, Llovd KO, Armour KL, Wallace TP, Harris WJ, Carr FJ, Old LJ: Specificity analysis of blood group Lewis-y {Le(y)} antibodies generatedagainst synthetic and natural Le(y) determinants. Proc Natl Acad Sci USA. 1994, 91: 12957-12961. 10.1073/pnas.91.26.12957.
Article
CAS
Google Scholar
Hokke CH, Neeleman AP, Koeleman CA, Eijnden van den DH: Identification of an alpha3-fucosyltransferase and a novel alpha2-fucosyltransferase activity in cercariae of the schistosome Trichobilharzia ocellata: biosynthesis of the Fucalpha1 → 2Fucalpha1 → 3[Gal(NAc)beta1 → 4]GlcNAc sequence. Glycobiology. 1998, 8: 393-406. 10.1093/glycob/8.4.393.
Article
CAS
Google Scholar
Dettke M, Pálfi G, Loibner H: Activation-dependent expression of the blood group-related Lewis Y antigen on peripheral blood granulocytes. J Leukoc Biol. 2000, 68: 511-514.
CAS
Google Scholar
Arai Y, Nishida M: Differential diagnosis between normal endometrium and endometrial hyperplasia with immunostaining cytology using anti-LeY monoclonal antibody. Int J Gynecol Cancer. 2003, 13: 42-46. 10.1046/j.1525-1438.2003.13009.x.
Article
CAS
Google Scholar
Madjd Z, Parsons T, Watson NF, Spendlove I, Ellis I, Durrant LG: High expression of Lewis y/b antigens is associated with decreased survival in lymph node negative breast carcinomas. Breast Cancer Res. 2005, 7: R780-R787. 10.1186/bcr1305.
Article
CAS
Google Scholar
Kim YS, Yuan M, Itzkowitz SH, Sun QB, Kaizu T, Palekar A, Trump BF, Hakomori S: Expression of LeY and extended LeY blood group-related antigens in human malignant, premalignant, and nonmalignant colonic tissues. Cancer Res. 1986, 46: 5985-5992.
CAS
Google Scholar
Yin BW, Finstad CL, Kitamura K, Federici MG, Welshinger M, Kudrvashov V, Hoskins WJ, Welt S, Lloyd KO: Serological and immunochemical analysis of Lewis y (Ley) blood group antigen expression in epithelial ovarian cancer. Int J Cancer. 1996, 65: 406-412. 10.1002/(SICI)1097-0215(19960208)65:4<406::AID-IJC2>3.0.CO;2-0.
Article
CAS
Google Scholar
Iwamori M, Tanaka K, Kubushiro K, Lin B, Kiguchi K, Ishiwata I, Tsukazaki K, Nozawa S: Alterations in the glyolipid composition and cellular properties of ovarian carcinoma-derived RMG-1 cells on transfection of the α1,2-fucosyltransferase gene. Cancer Sci. 2005, 96: 26-30.
Article
CAS
Google Scholar
Zhao Y, Lin B, Hao YY, Yan LM, Liu JJ, Zhu LC, Zhang SL: The effects of Lewis(y) antigen content on drug resistance to carboplatin in ovarian cancer line RMG-I. Prog Biochem Biophys. 2008, 35: 1175-1182.
CAS
Google Scholar
Hynes NE, MacDonald G: Erb receptors and signaling pathways in cancer. Curr Opin Cell Biol. 2009, 21: 185-193. 10.1016/j.ceb.2008.12.010.
Article
Google Scholar
Matsumoto A, Ichikawa T, Nakao K, Miyaaki H, Hirano K, Fujimito M, Akiyama M, Miuma S, Ozawa E, Shibata H, Takeshita S, Yamasaki H, Ikeda M, Kato N, Eguchi K: Interferon-alpha-induced mTOR activation is an anti-hepatitis C virus signal via the phosphatidylinositol 3-kinase-Akt-independent pathway. J Gastroenterol. 2009, 44: 856-863. 10.1007/s00535-009-0075-1.
Article
CAS
Google Scholar
Park S, Zhao D, Hatanpaa KJ, Mickey BE, Saha D, Boothman DA, Story MD, Wong ET, Burma S, Georgescu MM, Rangenkar VM, Chauncey SS, Habib AA: RIP1 activates PI3K-Akt via a dual mechanism involving NF-kappaB-mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and down-regulation of PTEN. Cancer Res. 2009, 69: 4107-4111. 10.1158/0008-5472.CAN-09-0474.
Article
CAS
Google Scholar
Djerf EA, Trinks C, Abdiu A, Thunell LK, Hallbeck AL, Walz TM: ErbB receptor tyrosine kinases contribute to proliferation of malignant melanoma cells: inhibition by gefitinib (ZD1839). Melanoma Res. 2009, 19: 156-166. 10.1097/CMR.0b013e32832c6339.
Article
CAS
Google Scholar
Basu A: Molecular targets of breast cancer: AKTing in concert. Breast Cancer. 2008, 2: 11-16.
CAS
Google Scholar
Dieterie A, Orth R, Daubrawa M, Grotemeier A, Alers S, Ullrich S, Lammers R, Wesselborg S, Stork B: The Akt inhibitor tricirbine sensitizes prostate carcinoma cells to TRAIL-induced apoptosis. Int J Cancer. 2009, 125: 932-941. 10.1002/ijc.24374.
Article
Google Scholar
Zhu K, Amin MA, Zha YY, Harlow LA, Koch AE: Mechanism by which H-2 g, a glucose analog of blood group H antigen, mediates angiogenesis. Blood. 2005, 105: 2343-2349. 10.1182/blood-2004-08-3140.
Article
CAS
Google Scholar
Sasak W, De Luca LM, Dion LD, Silverman-Jones CS: Effect of retionic acid on cell surface glycopeptides of cultured spontancously transformed mouse fibroblasts(BALB/c3T72-3 cells). Cancer Res. 1980, 40: 1944-1949.
CAS
Google Scholar
Prives C, Gottifredi V: The p21 and PCNA partnership: a new twist for an old plot. Cell Cycle. 2008, 7: 3840-3846.
Article
CAS
Google Scholar
Apweiler R, Hermjakob H, Sharon N: On the frequency of protein glycosylation, as deduced from analysis of the SWISS-PROT database. Biochim Biophys Acta. 1999, 1473: 4-8.
Article
CAS
Google Scholar
Narimatsu H: Human glycogene cloning: focus on beta 3-glycosyltransferase and beta 4-glycosyltransferase families. Curr Opin Struct Biol. 2006, 16: 567-575. 10.1016/j.sbi.2006.09.001.
Article
CAS
Google Scholar
Aamoudse CA, Bax M, Sánchez-Hernández M, García-Vallejo JJ, van Koovk Y: Glycan modification of the tumor antigen gp100 targets DC-SIGN to enhance dendritic cell induced antigen presentation to T cells. Int J Cancer. 2008, 122: 839-846. 10.1002/ijc.23101.
Article
Google Scholar
Nonaka M, Ma BY, Murai R, Nakamura N, Baba M, Kawasaki N, Hodohara K, Asano S: Glycosylation-Dependent Interactions of C-Type Lectin DC-SIGN with Colorectal Tumor-Associated Lewis Glycans Impair the Function and Differentiation of Monocyte-Derived Dendritic Cells. J Immunol. 2008, 180: 3347-3356.
Article
CAS
Google Scholar
Pai T, Chen Q, Zhang Y, Zolfaqhari R, Ross AC: Galactomutarotase and other galactose-related genes are rapidly induced by retinoic acid in human myeloid cells. Biochemistry. 2007, 46: 15198-151207. 10.1021/bi701891t.
Article
CAS
Google Scholar
Federici MF, Kudryashov V, Saigo PE, Finstad CL, Lloyd KO: Selection of carbohydrate antigens in human epithelial ovarian cancers as targets for immunotherapy: serous and mucinous tumors exhibit distinctive patterns of expression. Int J Cancer. 1999, 81: 193-198. 10.1002/(SICI)1097-0215(19990412)81:2<193::AID-IJC5>3.0.CO;2-S.
Article
CAS
Google Scholar
Zhu LC, Lin B, Hao YY, Li FF, Diao B, Zhang SL: Impact of alpha1,2-fucosyltransferase gene transfection on cancer related gene expression profile of human ovarian cancer cell line RMG-I. Ai Zheng. 2008, 27: 934-941.
CAS
Google Scholar
Klinger M, Farhan H, Just H, Drobny H, Himmler G, Loibner H, Mudde GC, Freissmuth M, Sexl V: Antibodies directed against Lewis-Y antigen inhibit signaling of Lewis-Y modified ErbB receptors. Cancer Res. 2004, 64: 1087-1093. 10.1158/0008-5472.CAN-03-2435.
Article
CAS
Google Scholar
Fraser M, Bai T, Tsang BK: Akt promotes cisplatin resistance in human ovarian cancer cells through inhibition of p53 phosphorylation and nuclear function. Int J Cancer. 2008, 22: 534-546. 10.1002/ijc.23086.
Article
Google Scholar
Kueck A, Opipari AW, Griffith KA, Tan L, Choi M, Huang J, Wahl H, Liu JR: Resveratrol inhibits glucose metabolism in human ovarian cancer cells. Gynecol Oncol. 2007, 103: 450-457. 10.1016/j.ygyno.2007.07.065.
Article
Google Scholar
Hemmings BA: Akt signaling: linking membrane events to life and death decisions. Science. 1997, 275: 628-630. 10.1126/science.275.5300.628.
Article
CAS
Google Scholar
Do TV, Kubba LA, Antenos M, Rademaker AW, Sturgis CD, Woodruff TK: The role of activin A and Akt/GSK signaling in ovarian tumor biology. Endocrinology. 2008, 149: 3809-3816. 10.1210/en.2007-1584.
Article
CAS
Google Scholar
Shtilbans V, Wu M, Burstein DE: Current overview of the role of Akt in cancer studies via applied immunohistochemistry. Ann Diagn Pathol. 2008, 12: 153-160. 10.1016/j.anndiagpath.2007.12.001.
Article
Google Scholar
Woenckhaus J, Steger K, Sturm K, Münstedt K, Franke FE, Fenic I: Prognostic value of PIK3CA and phosphorylated AKT expression in ovarian cancer. Virchows Arch. 2007, 450: 387-395. 10.1007/s00428-006-0358-3.
Article
CAS
Google Scholar
Azuma Y, Ito M, Taniguchi A, Matsumoto K: Expression of cell surface Lewis X and Y antigens and FUT mRNA is increased in Jurkat cells undergoing apoptosis. Biochim Biophys Acta. 2004, 1672: 157-163.
Article
CAS
Google Scholar
Inufusa H, Adachi T, Kivokawa T, Nakatani Y, Wakano T, Nakamura M, Okuno K, Shiozaki H, Yamamoto S, Suzuki M, Ando O, Kurimoto M, Miyake M, Yasutomi M: Ley glycolipid-recognizing monoclonal antibody inhibits procoagulant activity and metastasis of human adenocarcinoma. Int J Oncol. 2001, 19: 941-946.
CAS
Google Scholar
Cordel S, Goupille C, Hallouin E, Meflah K, Le Pendu J: Role for alpha1,2-fucosyltransferase and histo-blood group antigen H type 2 in resistance of rat colon carcinoma cells to 5-fluorouracil. Int J Cancer. 2000, 85: 142-148. 10.1002/(SICI)1097-0215(20000101)85:1<142::AID-IJC24>3.0.CO;2-K.
Article
CAS
Google Scholar
De Bolós C, Garrido M, Real FX: MUC6 apomucin shows a distinct normal tissue distribution that correlates with Lewis antigen expression in the human stomach. Gastroenterology. 1995, 109: 723-734. 10.1016/0016-5085(95)90379-8.
Article
Google Scholar
Basu A, Murthy U, Rodeck U, Herlyn M, Mattes L, Das M: Presence of tumor-associated antigens in epidermal growth factor receptors from different human carcinomas. Cancer Res. 1987, 47: 2531-2536.
CAS
Google Scholar
Wang XQ, Sun P, O'Gorman M, Tai T, Paller AS: Epidermal growth factor receptor glycosylation is required for ganglioside GM3 binding and GM3-mediated suppression [correction of suppression] of activation. Glycobiology. 2001, 11: 515-522. 10.1093/glycob/11.7.515.
Article
CAS
Google Scholar
Wang X, Zhang S, MacLennan GT, Eble JN, Lopez-Beltran A, Yang XJ, Pan CX, Zhou H, Montironi R, Cheng L: Epidermal growth factor receptor protein expression and gene amplification in small cell carcinoma of the urinary bladder. Clin Cancer Res. 2007, 13: 953-957. 10.1158/1078-0432.CCR-06-2167.
Article
CAS
Google Scholar
Guo P, Wang QY, Guo HB, Shen ZH, Chen HL: N-Acetylglucosaminyl-transferase V modifies the signaling pathway of epidermal growth factor receptor. Cell Mol Life Sci. 2004, 61: 1975-1804. 10.1007/s00018-004-4122-z.
Article
Google Scholar
Maines MD: Biliverdin reductase: PKC interaction at the cross-talk of MAPK and PI3K signaling pathways. Antioxid Redox Signal. 2007, 9: 2187-2195. 10.1089/ars.2007.1805.
Article
CAS
Google Scholar
Campbell M, Allen WE, Sawyer C, Vanhaesebroeck B, Trimble ER: Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the PI3K and MAPK signaling pathways. Circ Res. 2004, 95: 380-388. 10.1161/01.RES.0000138019.82184.5d.
Article
CAS
Google Scholar
Martin MM, Buckenberger JA, Jiang J, Malana GE, Knoell DL, Feldman DS, Elton TS: TGF-beta1 stimulates human AT1 receptor expression in lung fibroblasts by cross talk between the Smad, p38 MAPK, JNK, and PI3K signaling pathways. Am J Physiol Lung Cell Mol Physiol. 2007, 293: L790-L799. 10.1152/ajplung.00099.2007.
Article
CAS
Google Scholar
Westwood JA, Smyth MJ, Teng MW, Moeller M, Trapani JA, Scott AM, Smyth FE, Cartwright GA, Power BE, Hönemann D, Prince HM, Darcy PK, Kershaw MH: Adoptive transfer of T cells modified with a humanized chimeric receptor gene inhibits growth of Lewis-Y-expressing tumors in mice. Proc Natl Acad Sci USA. 2005, 102: 19051-19056. 10.1073/pnas.0504312102.
Article
CAS
Google Scholar
Halloran MM, Carley WW, Polverini PJ, Haskell CJ, Phan S, Anderson BJ, Woods JM, Campbell PL, Volin MV, Bäcker AE, Koch AE: Ley/H: an endothelial-selective, cytokine-inducible, angiogenic mediator. J Immunol. 2000, 164: 4868-4877.
Article
CAS
Google Scholar
Kudryashow V, Glunz PW, Williams LJ, Hintermann S, Danishefsky SJ, Lloyd KO: Toward optimized carbohydrate-based anticancer vaccines: epitope clustering, carrier structure, and adjuvant all influence antibody responses to Lewis y conjugates in mice. Proc Natl Acad Sci USA. 2001, 98: 3264-3269. 10.1073/pnas.051623598.
Article
Google Scholar
Livingston PO, Ragupathi G: Cancer vaccines targeting carbohydrate antigens. Hum Vaccin. 2006, 2: 137-143.
Article
CAS
Google Scholar