Murta-Nascimento C, Schmitz-Drager BJ, Zeegers MP, Steineck G, Kogevinas M, Real FX, Malats N: Epidemiology of urinary bladder cancer: from tumor development to patient’s death. World J Urol. 2007, 25: 285-295. 10.1007/s00345-007-0168-5.
Article
PubMed
Google Scholar
van Rhijn BW, Burger M, Lotan Y, Solsona E, Stief CG, Sylvester RJ, Witjes JA, Zlotta AR: Recurrence and progression of disease in non-muscle-invasive bladder cancer: from epidemiology to treatment strategy. Eur Urol. 2009, 56: 430-442. 10.1016/j.eururo.2009.06.028.
Article
PubMed
Google Scholar
Kiemeney LA, Sulem P, Besenbacher S, Vermeulen SH, Sigurdsson A, Thorleifsson G, Gudbjartsson DF, Stacey SN, Gudmundsson J, Zanon C, Kostic J, Masson G, Bjarnason H, Palsson ST, Skarphedinsson OB, Gudjonsson SA, Witjes JA, Grotenhuis AJ, Verhaegh GW, Bishop DT, Sak SC, Choudhury A, Elliott F, Barrett JH, Hurst CD, de Verdier PJ, Ryk C, Rudnai P, Gurzau E, Koppova K, et al: A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer. Nat Genet. 2010, 42: 415-419. 10.1038/ng.558.
Article
PubMed Central
CAS
PubMed
Google Scholar
Kiemeney LA, Thorlacius S, Sulem P, Geller F, Aben KK, Stacey SN, Gudmundsson J, Jakobsdottir M, Bergthorsson JT, Sigurdsson A, Blondal T, Witjes JA, Vermeulen SH, Hulsbergen-van de Kaa CA, Swinkels DW, Ploeg M, Cornel EB, Vergunst H, Thorgeirsson TE, Gudbjartsson D, Gudjonsson SA, Thorleifsson G, Kristinsson KT, Mouy M, Snorradottir S, Placidi D, Campagna M, Arici C, Koppova K, Gurzau E, et al: Sequence variant on 8q24 confers susceptibility to urinary bladder cancer. Nat Genet. 2008, 40: 1307-1312. 10.1038/ng.229.
Article
PubMed Central
CAS
PubMed
Google Scholar
Wu X, Ye Y, Kiemeney LA, Sulem P, Rafnar T, Matullo G, Seminara D, Yoshida T, Saeki N, Andrew AS, Dinney CP, Czerniak B, Zhang ZF, Kiltie AE, Bishop DT, Vineis P, Porru S, Buntinx F, Kellen E, Zeegers MP, Kumar R, Rudnai P, Gurzau E, Koppova K, Mayordomo JI, Sanchez M, Saez B, Lindblom A, de Verdier P, Steineck G, et al: Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer. Nat Genet. 2009, 41: 991-995. 10.1038/ng.421.
Article
PubMed Central
CAS
PubMed
Google Scholar
Wang M, Chu H, Yan F, Qin C, Li P, Yuan L, Yin C, Xu J, Zhang Z: Chromosome 4p16.3 variant modify bladder cancer risk in a Chinese population. Carcinogenesis. 2011, 32: 872-875. 10.1093/carcin/bgr060.
Article
PubMed Central
CAS
PubMed
Google Scholar
Ambros V: The functions of animal microRNAs. Nature. 2004, 431: 350-355. 10.1038/nature02871.
Article
CAS
PubMed
Google Scholar
Carthew RW, Sontheimer EJ: Origins and Mechanisms of miRNAs and siRNAs. Cell. 2009, 136: 642-655. 10.1016/j.cell.2009.01.035.
Article
PubMed Central
CAS
PubMed
Google Scholar
Suarez Y, Fernandez-Hernando C, Yu J, Gerber SA, Harrison KD, Pober JS, Iruela-Arispe ML, Merkenschlager M, Sessa WC: Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis. Proc Natl Acad Sci U S A. 2008, 105: 14082-14087. 10.1073/pnas.0804597105.
Article
PubMed Central
CAS
PubMed
Google Scholar
Gregory PA, Bracken CP, Bert AG, Goodall GJ: MicroRNAs as regulators of epithelial-mesenchymal transition. Cell Cycle. 2008, 7: 3112-3118. 10.4161/cc.7.20.6851.
Article
CAS
PubMed
Google Scholar
Bartel DP: MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004, 116: 281-297. 10.1016/S0092-8674(04)00045-5.
Article
CAS
PubMed
Google Scholar
Medina PP, Nolde M, Slack FJ: OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma. Nature. 2010, 467: 86-90. 10.1038/nature09284.
Article
CAS
PubMed
Google Scholar
Lujambio A, Calin GA, Villanueva A, Ropero S, Sánchez-Céspedes M, Blanco D, Montuenga LM, Rossi S, Nicoloso MS, Faller WJ, Gallagher WM, Eccles SA, Croce CM, Esteller M: A microRNA DNA methylation signature for human cancer metastasis. Proc Natl Acad Sci U S A. 2008, 105: 13556-13561. 10.1073/pnas.0803055105.
Article
PubMed Central
CAS
PubMed
Google Scholar
Gottardo F, Liu CG, Ferracin M, Calin GA, Fassan M, Bassi P, Sevignani C, Byrne D, Negrini M, Pagano F, Gomella LG, Croce CM, Baffa R: Micro-RNA profiling in kidney and bladder cancers. Urol Oncol. 2007, 25: 387-392. 10.1016/j.urolonc.2007.01.019.
Article
CAS
PubMed
Google Scholar
Puerta-Gil P, Garcia-Baquero R, Jia AY, Ocana S, Alvarez-Mugica M, Alvarez-Ossorio JL, Cordon-Cardo C, Cava F, Sanchez-Carbayo M: miR-143, miR-222, and miR-452 are useful as tumor stratification and noninvasive diagnostic biomarkers for bladder cancer. Am J Pathol. 2012, 180: 1808-1815. 10.1016/j.ajpath.2012.01.034.
Article
CAS
PubMed
Google Scholar
Feng Y, Liu J, Kang Y, He Y, Liang B, Yang P, Yu Z: miR-19a acts as an oncogenic microRNA and is up-regulated in bladder cancer. J Exp Clin Cancer Res: CR. 2014, 33: 67-10.1186/s13046-014-0067-8.
Article
PubMed Central
PubMed
Google Scholar
Wang X, Wu J, Lin Y, Zhu Y, Xu X, Xu X, Liang Z, Li S, Hu Z, Zheng X, Xie L: MicroRNA-320c inhibits tumorous behaviors of bladder cancer by targeting Cyclin-dependent kinase 6. J Exp Clin Cancer Res: CR. 2014, 33: 69-10.1186/s13046-014-0069-6.
Article
PubMed Central
PubMed
Google Scholar
Wang Q, Li P, Li A, Jiang W, Wang H, Wang J, Xie K: Plasma specific miRNAs as predictive biomarkers for diagnosis and prognosis of glioma. J Exp Clin Cancer Res: CR. 2012, 31: 97-10.1186/1756-9966-31-97.
Article
PubMed Central
CAS
PubMed
Google Scholar
Lodygin D, Tarasov V, Epanchintsev A, Berking C, Knyazeva T, Korner H, Knyazev P, Diebold J, Hermeking H: Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer. Cell Cycle. 2008, 7: 2591-2600. 10.4161/cc.7.16.6533.
Article
CAS
PubMed
Google Scholar
Wiggins JF, Ruffino L, Kelnar K, Omotola M, Patrawala L, Brown D, Bader AG: Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34. Cancer Res. 2010, 70: 5923-5930. 10.1158/0008-5472.CAN-10-0655.
Article
PubMed Central
CAS
PubMed
Google Scholar
Ji X, Wang Z, Geamanu A, Goja A, Sarkar FH, Gupta SV: Delta-tocotrienol suppresses Notch-1 pathway by upregulating miR-34a in nonsmall cell lung cancer cells. Int J Cancer J Int du Cancer. 2012, 131: 2668-2677. 10.1002/ijc.27549.
Article
CAS
Google Scholar
Vinall RL, Ripoll AZ, Wang S, Pan CX, DeVere White RW: MiR-34a chemosensitizes bladder cancer cells to cisplatin treatment regardless of p53-Rb pathway status. Int J Cancer J Int du Cancer. 2012, 130: 2526-2538. 10.1002/ijc.26256.
Article
CAS
Google Scholar
Nakatani F, Ferracin M, Manara MC, Ventura S, Del Monaco V, Ferrari S, Alberghini M, Grilli A, Knuutila S, Schaefer KL, Mattia G, Negrini M, Picci P, Serra M, Scotlandi K: miR-34a predicts survival of Ewing’s sarcoma patients and directly influences cell chemo-sensitivity and malignancy. J Pathol. 2012, 226: 796-805. 10.1002/path.3007.
Article
CAS
PubMed
Google Scholar
Li Y, Zou L, Li Q, Haibe-Kains B, Tian R, Li Y, Desmedt C, Sotiriou C, Szallasi Z, Iglehart JD, Richardson AL, Wang ZC: Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer. Nat Med. 2010, 16: 214-218. 10.1038/nm.2090.
Article
PubMed Central
PubMed
Google Scholar
Li H, Yu G, Shi R, Lang B, Chen X, Xia D, Xiao H, Guo X, Guan W, Ye Z, Xiao W, Xu H: Cisplatin-induced epigenetic activation of miR-34a sensitizes bladder cancer cells to chemotherapy. Mol Cancer. 2014, 13: 8-10.1186/1476-4598-13-8.
Article
PubMed Central
PubMed
Google Scholar
Ma Y, Qin H, Cui Y: MiR-34a targets GAS1 to promote cell proliferation and inhibit apoptosis in papillary thyroid carcinoma via PI3K/Akt/Bad pathway. Biochem Biophys Res Commun. 2013, 441: 958-963. 10.1016/j.bbrc.2013.11.010.
Article
CAS
PubMed
Google Scholar
Catto JW, Alcaraz A, Bjartell AS, De Vere WR, Evans CP, Fussel S, Hamdy FC, Kallioniemi O, Mengual L, Schlomm T, Visakorpi T: MicroRNA in prostate, bladder, and kidney cancer: a systematic review. Eur Urol. 2011, 59: 671-681. 10.1016/j.eururo.2011.01.044.
Article
CAS
PubMed
Google Scholar
Yu G, Li H, Wang J, Gumireddy K, Li A, Yao W, Tang K, Xiao W, Hu J, Xiao H, Lang B4, Ye Z, Huang Q, Xu H: MiRNA-34a Suppresses Cell Proliferation and Metastasis by Targeting CD44 in Human Renal Carcinoma Cells. J Urol. 2014, 192 (4): 1229-1237. 10.1016/j.juro.2014.05.094.
Article
CAS
PubMed
Google Scholar
Chan KS, Espinosa I, Chao M, Wong D, Ailles L, Diehn M, Gill H, Presti J, Chang HY, van de Rijn M, Shortliffe L, Weissman IL: Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Proc Natl Acad Sci U S A. 2009, 106: 14016-14021. 10.1073/pnas.0906549106.
Article
PubMed Central
CAS
PubMed
Google Scholar
Liu C, Kelnar K, Liu B, Chen X, Calhoun-Davis T, Li H, Patrawala L, Yan H, Jeter C, Honorio S, Wiggins JF, Bader AG, Fagin R, Brown D, Tang DG: The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat Med. 2011, 17: 211-215. 10.1038/nm.2284.
Article
PubMed Central
CAS
PubMed
Google Scholar
Jeong BJ, Liang ZL, Huang SM, Lim JS, Kim JM, Lee HJ: CD44 is associated with tumor recurrence and is an independent poor prognostic factor for patients with localized clear cell renal cell carcinoma after nephrectomy. Exp Ther Med. 2012, 3: 811-817.
PubMed Central
PubMed
Google Scholar
Bamias A, Chorti M, Deliveliotis C, Trakas N, Skolarikos A, Protogerou B, Legaki S, Tsakalou G, Tamvakis N, Dimopoulos MA: Prognostic significance of CA 125, CD44, and epithelial membrane antigen in renal cell carcinoma. Urology. 2003, 62: 368-373. 10.1016/S0090-4295(03)00264-4.
Article
CAS
PubMed
Google Scholar
Costa WH, Rocha RM, Cunha IW, Guimaraes GC, Zequi Sde C: Immunohistochemical expression of CD44s in renal cell carcinoma lacks independent prognostic significance. Int Braz J Urol. 2012, 38: 456-465. 10.1590/S1677-55382012000400004.
Article
PubMed
Google Scholar
Lin Y, Zhong Y, Guan H, Zhang X, Sun Q: CD44+/CD24- phenotype contributes to malignant relapse following surgical resection and chemotherapy in patients with invasive ductal carcinoma. J Exp Clin Cancer Res: CR. 2012, 31: 59-10.1186/1756-9966-31-59.
Article
PubMed Central
CAS
PubMed
Google Scholar
Chiofalo MG, Losito NS, Fulciniti F, Setola SV, Tommaselli A, Marone U, Di Cecilia ML, Pezzullo L: Axillary node metastasis from differentiated thyroid carcinoma with Hurthle and signet ring cell differentiation. A case of disseminated thyroid cancer with peculiar histologic findings. BMC cancer. 2012, 12: 55-10.1186/1471-2407-12-55.
Article
PubMed Central
CAS
PubMed
Google Scholar
Matuschek C, Lehnhardt M, Gerber PA, Poremba C, Hamilton J, Lammering G, Orth K, Budach W, Bojar H, Bolke E, Peiper M: Increased CD44s and decreased CD44v6 RNA expression are associated with better survival in myxofibrosarcoma patients: a pilot study. Eur J Med Res. 2014, 19: 6-10.1186/2047-783X-19-6.
Article
PubMed Central
PubMed
Google Scholar
Sugiyama M, Woodman A, Sugino T, Crowley S, Ho K, Smith J, Matsumura Y, Tarin D: Non-invasive detection of bladder cancer by identification of abnormal CD44 proteins in exfoliated cancer cells in urine. Clin Mol Pathol. 1995, 48: M142-147. 10.1136/mp.48.3.M142.
Article
PubMed Central
CAS
PubMed
Google Scholar
Yoshida GJ, Saya H: EpCAM expression in the prostate cancer makes the difference in the response to growth factors. Biochem Biophys Res Commun. 2014, 443: 239-245. 10.1016/j.bbrc.2013.11.093.
Article
CAS
PubMed
Google Scholar
Kim HR, Roe JS, Lee JE, Cho EJ, Youn HD: p53 regulates glucose metabolism by miR-34a. Biochem Biophys Res Commun. 2013, 437: 225-231. 10.1016/j.bbrc.2013.06.043.
Article
CAS
PubMed
Google Scholar
Yoshida GJ, Fuchimoto Y, Osumi T, Shimada H, Hosaka S, Morioka H, Mukai M, Masugi Y, Sakamoto M, Kuroda T: Li-Fraumeni syndrome with simultaneous osteosarcoma and liver cancer: increased expression of a CD44 variant isoform after chemotherapy. BMC Cancer. 2012, 12: 444-10.1186/1471-2407-12-444.
Article
PubMed Central
CAS
PubMed
Google Scholar
Yoshida GJ, Saya H: Inversed relationship between CD44 variant and c-Myc due to oxidative stress-induced canonical Wnt activation. Biochem Biophys Res Commun. 2014, 443: 622-627. 10.1016/j.bbrc.2013.12.016.
Article
CAS
PubMed
Google Scholar
Brown RL, Reinke LM, Damerow MS, Perez D, Chodosh LA, Yang J, Cheng C: CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression. J Clin Invest. 2011, 121: 1064-1074. 10.1172/JCI44540.
Article
PubMed Central
CAS
PubMed
Google Scholar
Croce CM: Causes and consequences of microRNA dysregulation in cancer. Nat Rev Genet. 2009, 10: 704-714. 10.1038/nrg2634.
Article
PubMed Central
CAS
PubMed
Google Scholar
Nugent M, Miller N, Kerin MJ: Circulating miR-34a levels are reduced in colorectal cancer. J Surg Oncol. 2012, 106: 947-952. 10.1002/jso.23174.
Article
CAS
PubMed
Google Scholar
Yamada H, Suzuki K, Ichino N, Ando Y, Sawada A, Osakabe K, Sugimoto K, Ohashi K, Teradaira R, Inoue T, Hamajima N, Hashimoto S: Associations between circulating microRNAs (miR-21, miR-34a, miR-122 and miR-451) and non-alcoholic fatty liver. Clin Chim Acta. 2013, 424: 99-103. 10.1016/j.cca.2013.05.021.
Article
CAS
PubMed
Google Scholar
Waldman SA, Terzic A: Translating MicroRNA discovery into clinical biomarkers in cancer. JAMA. 2007, 297: 1923-1925. 10.1001/jama.297.17.1923.
Article
CAS
PubMed
Google Scholar
Slaby O, Svoboda M, Michalek J, Vyzula R: MicroRNAs in colorectal cancer: translation of molecular biology into clinical application. Mol Cancer. 2009, 8: 102-10.1186/1476-4598-8-102.
Article
PubMed Central
PubMed
Google Scholar
Pang RT, Leung CO, Ye TM, Liu W, Chiu PC, Lam KK, Lee KF, Yeung WS: MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells. Carcinogenesis. 2010, 31: 1037-1044. 10.1093/carcin/bgq066.
Article
CAS
PubMed
Google Scholar
Yamamura S, Saini S, Majid S, Hirata H, Ueno K, Chang I, Tanaka Y, Gupta A, Dahiya R: MicroRNA-34a suppresses malignant transformation by targeting c-Myc transcriptional complexes in human renal cell carcinoma. Carcinogenesis. 2012, 33: 294-300. 10.1093/carcin/bgr286.
Article
PubMed Central
CAS
PubMed
Google Scholar
Li J, Zhou BP: Activation of beta-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters. BMC Cancer. 2011, 11: 49-10.1186/1471-2407-11-49.
Article
PubMed Central
PubMed
Google Scholar
de Antonellis P, Medaglia C, Cusanelli E, Andolfo I, Liguori L, De Vita G, Carotenuto M, Bello A, Formiggini F, Galeone A, De Rosa G, Virgilio A, Scognamiglio I, Sciro M, Basso G, Schulte JH, Cinalli G, Iolascon A, Zollo M: MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133+ tumor-propagating cells and supports neural differentiation in medulloblastoma. PLoS One. 2011, 6: e24584-10.1371/journal.pone.0024584.
Article
PubMed Central
CAS
PubMed
Google Scholar