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  1. New drugs to tackle the next pathway or mutation fueling cancer are constantly proposed, but 97% of them are doomed to fail in clinical trials, largely because they are identified by cellular or in silico scre...

    Authors: Ambra Cappelletto, Edoardo Alfì, Nina Volf, Thi Van Anh Vu, Francesca Bortolotti, Giulio Ciucci, Simone Vodret, Marco Fantuz, Martina Perin, Andrea Colliva, Giacomo Rozzi, Matilde Rossi, Giulia Ruozi, Lorena Zentilin, Roman Vuerich, Daniele Borin…
    Citation: Journal of Experimental & Clinical Cancer Research 2024 43:15
    Content type: Research Published on:

  2. Metastasis has emerged as the major reason of treatment failure and mortality in patients with nasopharyngeal carcinoma (NPC). Growing evidence links abnormal DNA methylation to the initiation and progression ...

    Authors: Shi-Qing Zhou, Ping Feng, Ming-Liang Ye, Sheng-Yan Huang, Shi-Wei He, Xun-Hua Zhu, Jun Chen, Qun Zhang and Ying-Qing Li
    Citation: Journal of Experimental & Clinical Cancer Research 2024 43:14
    Content type: Research Published on:

  3. Inflammation in the eye is often associated with aggravated ocular diseases such as uveal melanoma (UM). Poor prognosis of UM is generally associated with high potential of metastatic liver dissemination. A st...

    Authors: Shi Yong Neo, Mariana M. S. Oliveira, Le Tong, Yi Chen, Ziqing Chen, Sonia Cismas, Nutsa Burduli, Anna Malmerfelt, Joey Kay Hui Teo, Kong-Peng Lam, Evren Alici, Leonard Girnita, Arnika K. Wagner, Lisa S. Westerberg and Andreas Lundqvist
    Citation: Journal of Experimental & Clinical Cancer Research 2024 43:13
    Content type: Research Published on:

  4. Targeted therapies, including small molecule inhibitors directed against aberrant kinase signaling and chromatin regulators, are emerging treatment options for high-grade gliomas (HGG). However, when translati...

    Authors: Lea M. Stitzlein, Jack T. Adams, Erin N. Stitzlein, Richard W. Dudley and Joya Chandra
    Citation: Journal of Experimental & Clinical Cancer Research 2024 43:12
    Content type: Review Published on:

  5. Radiotherapy-activated NBTXR3 (NBTXR3 + RT) has demonstrated superior efficacy in cancer cell destruction and tumor growth control, compared to radiotherapy (RT), in preclinical and clinical settings. Previous...

    Authors: Jordan Da Silva, Célia Bienassis, Peter Schmitt, Céline Berjaud, Mickael Guedj and Sébastien Paris
    Citation: Journal of Experimental & Clinical Cancer Research 2024 43:11
    Content type: Research Published on:

  6. The variability in responses to neoadjuvant treatment with anti-HER2 antibodies prompts to personalized clinical management and the development of innovative treatment strategies. Tumor-infiltrating Natural Ki...

    Authors: Sara Santana-Hernández, Jesús Suarez-Olmos, Sonia Servitja, Pau Berenguer-Molins, Marcel Costa-Garcia, Laura Comerma, Anna Rea, Julia Perera-Bel, Silvia Menendez, Oriol Arpí, Begoña Bermejo, María Teresa Martínez, Juan Miguel Cejalvo, Iñaki Comino-Méndez, Javier Pascual, Emilio Alba…
    Citation: Journal of Experimental & Clinical Cancer Research 2024 43:10
    Content type: Research Published on:

  7. Podoplanin (PDPN) is a highly conserved, mucin-type protein specific to the lymphatic system. Overexpression of PDPN is associated with the progression of various solid tumors, and plays an important roles in ...

    Authors: Chunyan Feng, Albert Yu, Zhongfu Wang, Kun Wang, Jiawei Chen, Yaojiong Wu, Ting Deng, Huaqing Chen, Yibo Hou, Shaohua Ma, Xiaoyong Dai and Laiqiang Huang
    Citation: Journal of Experimental & Clinical Cancer Research 2024 43:9
    Content type: Research Published on:

  8. Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid tumors. The tumor immune microenvironment (TIME) formed by interactions among cancer cells, immune cells, cancer-associated fibroblasts (...

    Authors: Wenyu Luo, Ti Wen and Xiujuan Qu
    Citation: Journal of Experimental & Clinical Cancer Research 2024 43:8
    Content type: Review Published on:

    The Correction to this article has been published in Journal of Experimental & Clinical Cancer Research 2024 43:21

  9. Chemoresistance presents a significant obstacle in the treatment of colorectal cancer (CRC), yet the molecular basis underlying CRC chemoresistance remains poorly understood, impeding the development of new th...

    Authors: Xiaojian Zhu, Changxue Li, Yunfei Gao, Qingyuan Zhang, Tao Wang, Huaixiang Zhou, Fanqin Bu, Jia Chen, Xinjun Mao, Yulong He, Kaiming Wu, Ningning Li and Hongliang Luo
    Citation: Journal of Experimental & Clinical Cancer Research 2024 43:7
    Content type: Research Published on:

  10. About 10% of NSCLCs are mutated in KRAS and impaired in STK11/LKB1, a genetic background associated with poor prognosis, caused by an increase in metastatic burden and resistance to standard therapy. LKB1 is a pr...

    Authors: Gloriana Ndembe, Ilenia Intini, Massimo Moro, Chiara Grasselli, Andrea Panfili, Nicolò Panini, Augusto Bleve, Mario Occhipinti, Cristina Borzi, Marina Chiara Garassino, Mirko Marabese, Simone Canesi, Eugenio Scanziani, Gabriella Sozzi, Massimo Broggini and Monica Ganzinelli
    Citation: Journal of Experimental & Clinical Cancer Research 2024 43:6
    Content type: Research Published on:

  11. Tumor-associated inflammation suggests that anti-inflammatory medication could be beneficial in cancer therapy. Loratadine, an antihistamine, has demonstrated improved survival in certain cancers. However, the...

    Authors: Xiwen Liu, Ran Zhong, Jiaxing Huang, Zisheng Chen, Haoxiang Xu, Lixuan Lin, Qi Cai, Miao He, Shen Lao, Hongsheng Deng, Caichen Li, Jianfu Li, Yongmei Zheng, Xiaoyan Liu, Riqi Zeng, Jianxing He…
    Citation: Journal of Experimental & Clinical Cancer Research 2024 43:5
    Content type: Research Published on:

  12. Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest types of cancer and the chemotherapies such as gemcitabine/nab-paclitaxel are confronted with intrinsic or acquired resistance. The aim of this s...

    Authors: Cecilia Bergonzini, Alessandro Gregori, Tessa M. S. Hagens, Vera E. van der Noord, Bob van de Water, Annelien J. M. Zweemer, Bircan Coban, Mjriam Capula, Giulia Mantini, Asia Botto, Francesco Finamore, Ingrid Garajova, Liam A. McDonnell, Thomas Schmidt, Elisa Giovannetti and Erik H. J. Danen
    Citation: Journal of Experimental & Clinical Cancer Research 2024 43:4
    Content type: Research Published on:

  13. Lung cancer is a malignant tumor with the highest mortality worldwide. Abnormalities in the ubiquitin proteasome system are considered to be contributed to lung cancer progression with deleterious effects. DDB...

    Authors: Shan Wei, Jing Xing, Jia Chen, Liping Chen, Jiapei Lv, Xiaofei Chen, Tang Li, Tao Yu, Huaying Wang, Kai Wang and Wanjun Yu
    Citation: Journal of Experimental & Clinical Cancer Research 2024 43:3
    Content type: Research Published on:

  14. Cisplatin (CDDP)-based chemotherapy is a standard first-line treatment for metastatic bladder cancer (BCa) patients, and chemoresistance remains a major challenge in clinical practice. Circular RNAs (circRNAs)...

    Authors: Wenjie Wei, Kan Liu, Xing Huang, Shuo Tian, Hanfeng Wang, Chi Zhang, Jiali Ye, Yuhao Dong, Ziyan An, Xin Ma, Baojun Wang, Yan Huang and Xu Zhang
    Citation: Journal of Experimental & Clinical Cancer Research 2024 43:2
    Content type: Research Published on:

  15. Ceramide metabolism is crucial in the progress of brain metastasis (BM). However, it remains unexplored whether targeting ceramide metabolism may arrest BM.

    Authors: Ying Lin, Yun Wu, Qiangzu Zhang, Xunwei Tu, Sufang Chen, Junfan Pan, Nengluan Xu, Ming Lin, Peiwei She, Gang Niu, Yusheng Chen and Hongru Li
    Citation: Journal of Experimental & Clinical Cancer Research 2024 43:1
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Experimental & Clinical Cancer Research 2024 43:37

  16. In recent years, research focused on the multifaceted landscape and functions of cancer-associated fibroblasts (CAFs) aimed to reveal their heterogeneity and identify commonalities across diverse tumors for mo...

    Authors: Roberta Melchionna, Paola Trono, Anna Di Carlo, Francesca Di Modugno and Paola Nisticò
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:347
    Content type: Review Published on:

  17. Atypical teratoid rhabdoid tumors (ATRT) is a rare but aggressive malignancy in the central nervous system, predominantly occurring in early childhood. Despite aggressive treatment, the prognosis of ATRT patie...

    Authors: Le Hien Giang, Kuo-Sheng Wu, Wei-Chung Lee, Shing-Shung Chu, Anh Duy Do, Chun A. Changou, Huy Minh Tran, Tsung-Han Hsieh, Hsin-Hung Chen, Chia-Ling Hsieh, Shian-Ying Sung, Alice L. Yu, Yun Yen, Tai-Tong Wong and Che-Chang Chang
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:346
    Content type: Research Published on:

  18. Authors: Yuanshan Yao, Chunji Chen, Jing Wang, Haojie Xuan, Xiuxiu Chen, Zheng Li, Fuzhi Yang, Bin Wang, Siyun Lin, Saitian Li, Dongfang Tang, Libao Gong and Wen Gao
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:345
    Content type: Correction Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2023 42:330

  19. Research has indicated that long-term sleep deprivation can lead to immune dysfunction and participate in the occurance and progression of tumors. However, the relationship between sleep deprivation and colon ...

    Authors: Haijun Bao, Zuojie Peng, Xukai Cheng, Chenxing Jian, Xianguo Li, Yongping Shi, Wenzhong Zhu, Yuan Hu, Mi Jiang, Jia Song, Feifei Fang, Jinhuang Chen and Xiaogang Shu
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:344
    Content type: Research Published on:

  20. In vitro models are necessary to study the pathophysiology of the disease and the development of effective, tailored treatment methods owing to the complexity and heterogeneity of breast cancer and the large p...

    Authors: Anamitra Bhattacharya, Kamare Alam, Nakka Sharmila Roy, Kulwinder Kaur, Santanu Kaity, Velayutham Ravichandiran and Subhadeep Roy
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:343
    Content type: Review Published on:

  21. More than 90% of the mortality of triple-negative breast cancer (TNBC) patients is attributed to cancer metastasis with organotropism. The lung is a frequent site of TNBC metastasis. However, the precise molec...

    Authors: Shaojie Cheng, Xueying Wan, Liping Yang, Yilu Qin, Shanchun Chen, Yongcan Liu, Yan Sun, Yuxiang Qiu, Luyi Huang, Qizhong Qin, Xiaojiang Cui, Mingjun Wu and Manran Liu
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:342
    Content type: Research Published on:

  22. Chimeric antigen receptor (CAR) T-cells are a promising approach in cancer immunotherapy, particularly for treating hematologic malignancies. Yet, their effectiveness is limited when tackling solid tumors, whe...

    Authors: Liliana R. Loureiro, Lydia Hoffmann, Christin Neuber, Luise Rupp, Claudia Arndt, Alexandra Kegler, Manja Kubeil, Christoph E. Hagemeyer, Holger Stephan, Marc Schmitz, Anja Feldmann and Michael Bachmann
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:341
    Content type: Research Published on:

  23. Cancer cells undergo cellular adaptation through metabolic reprogramming to sustain survival and rapid growth under various stress conditions. However, how brain tumors modulate their metabolic flexibility in ...

    Authors: Hye Jin Yun, Min Li, Dong Guo, So Mi Jeon, Su Hwan Park, Je Sun Lim, Su Bin Lee, Rui Liu, Linyong Du, Seok-Ho Kim, Tae Hwan Shin, Seong-il Eyun, Yun-Yong Park, Zhimin Lu and Jong-Ho Lee
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:340
    Content type: Research Published on:

  24. Within the tumor immune microenvironment (TME), tumor-associated macrophages (TAMs) are crucial in modulating polarization states to influence cancer development through metabolic reprogramming. While long non...

    Authors: Jiayu Lin, Yihao Liu, Pengyi Liu, Wenxin Qi, Jia Liu, Xingfeng He, Qian Liu, Zehua Liu, Jingxin Yin, Jiewei Lin, Haili Bao and Jianhong Lin
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:339
    Content type: Research Published on:

  25. Oncogenic KRAS mutation, the most frequent mutation in non-small cell lung cancer (NSCLC), is an aggressiveness risk factor and leads to the metabolic reprogramming of cancer cells by promoting glucose, glutamine...

    Authors: Dasom Kim, Dongwha Min, Joohee Kim, Min Jung Kim, Yerim Seo, Byung Hwa Jung, Seung‑Hae Kwon, Hyunju Ro, Seoee Lee, Jason K. Sa and Ji-Yun Lee
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:338
    Content type: Research Published on:

  26. Myeloid cells (granulocytes and monocytes/macrophages) play an important role in neuroblastoma. By inducing a complex immunosuppressive network, myeloid cells pose a challenge for the adaptive immune system to...

    Authors: Marjolein C. Stip, Loes Teeuwen, Miranda P. Dierselhuis, Jeanette H. W. Leusen and Daniëlle Krijgsman
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:337
    Content type: Review Published on:

  27. Cancer-endothelial interplay is crucial for tumor behavior, yet the molecular mechanisms involved are largely unknown. Interleukin(IL)-30, which is expressed as a membrane-anchored cytokine by human prostate c...

    Authors: Stefania Livia Ciummo, Carlo Sorrentino, Cristiano Fieni and Emma Di Carlo
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:336
    Content type: Research Published on:

  28. Head and neck squamous cell carcinoma (HNSCC) is one of the most common malignant tumors globally. Understanding the molecular basis of tumor progression and drug resistance can offer innovative strategies to ...

    Authors: Li Cui, Ye Lu, Jiarong Zheng, Bing Guo and Xinyuan Zhao
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:335
    Content type: Research Published on:

  29. With the advancements in bioinformatic technology, an increasing number of circular RNAs (circRNAs) have been discovered and their crucial roles in the development and progression of various malignancies have ...

    Authors: Zhenzhou Chen, Yidan Li, Kuan He, Jianguo Yang, Qican Deng, Yajun Chen and Zhongxue Fu
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:334
    Content type: Research Published on:

  30. In addition to anti-PD(L)1, anti-CTLA-4 and anti-LAG-3, novel immune checkpoint proteins (ICP)-targeted antibodies have recently failed to demonstrate significant efficacy in clinical trials. In these trials, ...

    Authors: Delphine Bredel, Edi Tihic, Séverine Mouraud, François-Xavier Danlos, Sandrine Susini, Marine Aglave, Alexia Alfaro, Chifaou Mohamed-Djalim, Mathieu Rouanne, Héloise Halse, Amélie Bigorgne, Lambros Tselikas, Stéphane Dalle, Dana M. Hartl, Eric Baudin, Catherine Guettier…
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:333
    Content type: Research Published on:

  31. Authors: Sang-Yun Lee, Hyeong Jun Cho, Jimin Choi, Bosung Ku, Seok Whan Moon, Mi Hyoung Moon, Kyung Soo Kim, Kwanyong Hyun, Tae-Jung Kim, Yeoun Eun Sung, Yongki Hwang, Eunyoung Lee, Dong Hyuck Ahn, Joon Young Choi, Jeong Uk Lim, Chan Kwon Park…
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:332
    Content type: Correction Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2023 42:309

  32. Colorectal cancer (CRC) is one of the most common malignancies and is characterized by reprogrammed metabolism. Ferroptosis, a programmed cell death dependent on iron, has emerged as a promising strategy for C...

    Authors: Chang Xu, Zhixuan Bian, Xinyue Wang, Na Niu, Li Liu, Yixuan Xiao, Jiabei Zhu, Nan Huang, Yue Zhang, Yan Chen, Qi Wu, Fenyong Sun, Xiaoli Zhu and Qiuhui Pan
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:331
    Content type: Research Published on:

  33. CircRNA is recognized for its significant regulatory function across various cancers. However, its regulatory role in non-small cell lung cancer (NSCLC) is still largely uncharted.

    Authors: Yuanshan Yao, Chunji Chen, Jing Wang, Haojie Xuan, Xiuxiu Chen, Zheng Li, Fuzhi Yang, Bin Wang, Siyun Lin, Saitian Li, Dongfang Tang, Libao Gong and Wen Gao
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:330
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Experimental & Clinical Cancer Research 2023 42:345

  34. Hedgehog-Gli1 signaling induces development of two common neurological features seen in pancreatic ductal adenocarcinoma (PDAC): peripheral neural invasion (PNI) and peripheral neural remodeling (PNR). However...

    Authors: Weiqi Dai, Xiaoli Wu, Jingjing Li, Wenxi Tang, Ying Wang, Wenqiang Xu, Dengyu Han, Xiaorong Xu and Xuanfu Xu
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:329
    Content type: Research Published on:

  35. Lung metastasis is the most adverse clinical factor and remains the leading cause of osteosarcoma-related death. Deciphering the mechanisms driving metastatic spread is crucial for finding open therapeutic win...

    Authors: Sara F.F. Almeida, Liliana Santos, Gabriela Sampaio-Ribeiro, Hugo R.S. Ferreira, Nuno Lima, Rui Caetano, Mónica Abreu, Mónica Zuzarte, Ana Sofia Ribeiro, Artur Paiva, Tânia Martins-Marques, Paulo Teixeira, Rui Almeida, José Manuel Casanova, Henrique Girão, Antero J. Abrunhosa…
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:328
    Content type: Research Published on:

  37. As a small G protein of Ras family, Ras-like-without-CAAX-1 (RIT1) plays a critical role in various tumors. Our previous study has demonstrated the involvement of RIT1 in promoting malignant progression of hep...

    Authors: Yang Su, Hechun Lin, Junming Yu, Lin Mao, Wenjiao Jin, Tengfei Liu, Shuqing Jiang, Yunyu Wu, Saihua Zhang, Qin Geng, Chao Ge, Fangyu Zhao, Taoyang Chen, Ying Cui, Jinjun Li, Helei Hou…
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:326
    Content type: Research Published on:

  38. Breast cancer is the global leading cancer burden in women and the hormone receptor-positive (HR+) subtype is a major part of breast cancer. Though cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors are highl...

    Authors: Nar Bahadur Katuwal, Min Sil Kang, Mithun Ghosh, Sa Deok Hong, Yeong Gyu Jeong, Seong Min Park, Seul-Gi Kim, Joohyuk Sohn, Tae Hoen Kim and Yong Wha Moon
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:325
    Content type: Research Published on:

  39. Cancer-associated fibroblasts (CAFs) play pivotal roles in chemoresistance of pancreatic ductal adenocarcinoma (PDAC). However, the underlying mechanisms are poorly understood. Revealing the cross-talk network...

    Authors: Shangyou Zheng, Qing Tian, Yuan Yuan, Shuxin Sun, Tingting Li, Renpeng Xia, Rihua He, Yuming Luo, Qing Lin, Zhiqiang Fu, Yu Zhou, Rufu Chen and Chonghui Hu
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:324
    Content type: Research Published on:

  40. Pancreatic ductal adenocarcinoma (PDAC) is a profoundly aggressive and fatal cancer. One of the key factors defining its aggressiveness and resilience against chemotherapy is the existence of cancer stem cells...

    Authors: Quan Zheng, Jiajia Tang, Alexandra Aicher, Tony Bou Kheir, Berina Sabanovic, Preeta Ananthanarayanan, Chiara Reina, Minchun Chen, Jian-Min Gu, Bin He, Sonia Alcala, Diana Behrens, Rita T. Lawlo, Aldo Scarpa, Manuel Hidalgo, Bruno Sainz Jr.…
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:323
    Content type: Research Published on:

  41. Lines of evidence indicated that, immune checkpoints (ICs) inhibitors enhanced T cell immune response to exert anti-tumor effects. However, T cell exhaustion has been so far a major obstacle to antitumor immun...

    Authors: Yan Lv, Mengyuan Li, Ling Weng, Haoying Huang, Yujie Mao, Danchen Aaron Yang, Qingyun Wei, Mengmeng Zhao, Qin Wei, Ke Rui, Xuan Han, Weiwei Fan, Xueting Cai, Peng Cao and Meng Cao
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:322
    Content type: Research Published on:

  42. Authors: Jianfa Li, Chengle Zhuang, Yuchen Liu, Mingwei Chen, Yincong Chen, Zhicong Chen, Anbang He, Junhao Lin, Yonghao Zhan, Li Liu, Wen Xu, Guoping Zhao, Yinglu Guo, Hanwei Wu, Zhiming Cai and Weiren Huang
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:321
    Content type: Correction Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2016 35:99

  43. Epigenetic alterations play an important role in hepatocellular carcinoma (HCC) development. Enhancer of zeste homolog 2 (EZH2) is a well-known epigenetic modifier that functions as an oncogene in tumors by pr...

    Authors: Ke Wang, Xunliang Jiang, Yu Jiang, Jun Liu, Yongtao Du, Zecheng Zhang, Yunlong Li, Xinhui Zhao, Jipeng Li and Rui Zhang
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:320
    Content type: Research Published on:

  44. It has been demonstrated that circularRNA (circRNAs) plays a critical role in various cancers. While the potential molecular mechanism of circRNAs in the progression of colorectal cancer (CRC) remains uncertain.

    Authors: Jialin Song, Qing Liu, Lei Han, Tiantian Song, Sihao Huang, Xinyao Zhang, Qiuming He, Chenxi Liang, Shuai Zhu and Bin Xiong
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:319
    Content type: Research Published on:

  45. TGFβ induces several cell phenotypes including senescence, a stable cell cycle arrest accompanied by a secretory program, and epithelial-mesenchymal transition (EMT) in normal epithelial cells. During carcinog...

    Authors: Anda Huna, Jean-Michel Flaman, Catalina Lodillinsky, Kexin Zhu, Gabriela Makulyte, Victoria Pakulska, Yohann Coute, Clémence Ruisseaux, Pierre Saintigny, Hector Hernandez-Vargas, Pierre-Antoine Defossez, Mathieu Boissan, Nadine Martin and David Bernard
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:318
    Content type: Research Published on:

  46. BRAF-mutant melanoma patients benefit from the combinatorial treatments with BRAF and MEK inhibitors. However, acquired drug resistance strongly limits the efficacy of these targeted therapies in time. Recentl...

    Authors: Vittorio Castaldo, Michele Minopoli, Francesca Di Modugno, Andrea Sacconi, Domenico Liguoro, Rachele Frigerio, Arianna Ortolano, Marta Di Martile, Luisa Gesualdi, Gabriele Madonna, Mariaelena Capone, Roberto Cirombella, Angiolina Catizone, Donatella Del Bufalo, Andrea Vecchione, Maria Vincenza Carriero…
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:317
    Content type: Research Published on:

  47. Cancer-associated fibroblasts (CAFs), the predominant stromal cell of tumor microenvironment (TME), play an important role in tumor progression and immunoregulation by remodeling extracellular matrix (ECM) and...

    Authors: Zhao Zhang, Yongbo Yu, Zhilei Zhang, Dan Li, Zhijuan Liang, Liping Wang, Yuanbin Chen, Ye Liang and Haitao Niu
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:316
    Content type: Research Published on:

  48. Image-based screening improves the detection of early-stage lung adenocarcinoma (LUAD)but also highlights the issue of high false-positive diagnoses, which puts patients at a risk of unnecessary over-treatment...

    Authors: Yibei Wang, Ziwei Miao, Xiaoxue Qin, Yi Yang, Si Wu, Qi Miao, Beibei Li, Mingyu Zhang, Pengfei Wu, Yun Han and Bo Li
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:315
    Content type: Research Published on:

  49. Authors: Shanqiang Qu, Songtao Qi, Huayang Zhang, Zhiyong Li, Kaicheng Wang, Taichen Zhu, Rongxu Ye, Wanghao Zhang, Guanglong Huang and Guo-zhong Yi
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:314
    Content type: Correction Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2023 42:285

  50. Recent evidence reveals the emerging functions of circular RNA (circRNA) and protein glycosylation in cancer progression. However, the roles of circRNA in regulating glycosyltransferase expression in gastric c...

    Authors: Hongjun Li, Wanju Jiao, Jiyu Song, Jianqun Wang, Guo Chen, Dan Li, Xiaojing Wang, Banghe Bao, Xinyi Du, Yang Cheng, Chunhui Yang, Qiangsong Tong and Liduan Zheng
    Citation: Journal of Experimental & Clinical Cancer Research 2023 42:313
    Content type: Research Published on:

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Journal of Experimental & Clinical Cancer Research

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