Skip to main content

Articles

Page 56 of 76

  1. Authors: Yiting Tang, Yayun Cui, Zengpeng Li, Zhuqing Jiao, Yong Zhang, Yan He, Guangxia Chen, Qunyan Zhou, Wenjie Wang, Xifa Zhou, Judong Luo and Shuyu Zhang
    Citation: Journal of Experimental & Clinical Cancer Research 2016 35:20

    The original article was published in Journal of Experimental & Clinical Cancer Research 2016 35:7

  2. Emerging evidence demonstrates that microRNAs (miRNAs) play an important role in regulation of cell growth, invasion and metastasis through inhibiting the expression of their targets. It has been reported that...

    Authors: Yang Liu, Yumei Li, Rui Wang, Shukui Qin, Jing Liu, Fang Su, Yan Yang, Fuyou Zhao, Zishu Wang and Qiong Wu
    Citation: Journal of Experimental & Clinical Cancer Research 2016 35:19
  3. Dendritic cells (DCs) have been used successfully in clinical pilot studies. However, tumor-specific immunity and clinical responses were only induced in certain cancer patients. It has been well documented th...

    Authors: Fan-Qin Wei, Wei Sun, Thian-Sze Wong, Wei Gao, Yi-Hui Wen, Jia-Wei Wei, Yi Wei and Wei-Ping Wen
    Citation: Journal of Experimental & Clinical Cancer Research 2016 35:18
  4. MicroRNAs (miRNAs) have been shown to play a critical role in the development and progression of nasopharyngeal carcinoma (NPC). Although accumulating studies have been performed on the molecular mechanisms of...

    Authors: Fan Wang, Juan Lu, Xiaohong Peng, Jie Wang, Xiong Liu, Xiaomei Chen, Yiqi Jiang, Xiangping Li and Bao Zhang
    Citation: Journal of Experimental & Clinical Cancer Research 2016 35:17

    The Correction to this article has been published in Journal of Experimental & Clinical Cancer Research 2022 41:84

  5. Neuropilin-1 (NRP-1) is a transmembrane glycoprotein participating in the growth and metastasis of cancer cells as multifunctional co-receptors by interacting with the signaling pathways. However, its role in ...

    Authors: Linhao Li, Xian Jiang, Qian Zhang, Xuesong Dong, Yuqiang Gao, Yuanlong He, Haiquan Qiao, Fangyu Xie, Xiangjun Xie and Xueying Sun
    Citation: Journal of Experimental & Clinical Cancer Research 2016 35:16
  6. HOXA1 is a member of the Homeobox gene family, which encodes a group of highly conserved transcription factors that are important in embryonic development. However, it has been reported that HOXA1 exhibits onc...

    Authors: Chenwei Yuan, Xingwu Zhu, Yang Han, Chenlong Song, Chenchen Liu, Su Lu, Meng Zhang, Fudong Yu, Zhihai Peng and Chongzhi Zhou
    Citation: Journal of Experimental & Clinical Cancer Research 2016 35:15
  7. The aberrant expression of sperm-associated antigen 9 (SPAG9) is associated with numerous cancers, including hepatocellular carcinoma (HCC). The exploration of molecules and mechanisms regulating SPAG9 express...

    Authors: Guohua Lou, Xuejun Dong, Caixia Xia, Bingjue Ye, Qiuyue Yan, Shanshan Wu, Ye Yu, Feifei Liu, Min Zheng, Zhi Chen and Yanning Liu
    Citation: Journal of Experimental & Clinical Cancer Research 2016 35:14
  8. Interleukin-37 (IL-37), a newly identified member of the IL-1 family, has been known to play an immunosuppressive role in a variety of inflammatory disorders, but whether it participates in the regulation of p...

    Authors: Guanqun Ge, Aiqin Wang, Jingyue Yang, Yan Chen, Jin Yang, Yize Li and Yan Xue
    Citation: Journal of Experimental & Clinical Cancer Research 2016 35:13
  9. Both tumor-associated macrophages (TAMs) and the epithelial to mesenchymal transition (EMT) of cancer cells play key roles in promoting tumor progression. However, whether TAMs could induce EMT in the progress...

    Authors: Yong Hu, Meng-Ying He, Li-Fang Zhu, Cong-Chong Yang, Mei-Ling Zhou, Qiong Wang, Wei Zhang, Yang-Yu Zheng, Dong-Miao Wang, Zeng-Qi Xu, Yu-Nong Wu and Lai-Kui Liu
    Citation: Journal of Experimental & Clinical Cancer Research 2016 35:12
  10. MicroRNA-106b (miR-106b) was recently identified as an oncogene participating in cancer progression. Transforming growth factor β1(TGF-β1) is an indispensable cytokine regulating the local microenvironment, th...

    Authors: Yuan Cheng, Yanli Guo, Youyi Zhang, Ke You, Zijian Li and Li Geng
    Citation: Journal of Experimental & Clinical Cancer Research 2016 35:11
  11. MicroRNAs (miRNAs) are a class of small non-coding RNAs, which post-transcriptionally repress the expression of genes involved in cancer initiation and progression. Although some miRNAs that target many signal...

    Authors: Xiaochun Sun, Manhua Cui, Aichen Zhang, Lingling Tong, Kun Wang, Kai Li, Xue Wang, Ziqian Sun and Hongye Zhang
    Citation: Journal of Experimental & Clinical Cancer Research 2016 35:10
  12. In this study we explored the role of microRNAs (miRNAs) as mediators of leukemogenic effects of the fusion gene MLL-AF9, which results from a frequent chromosomal translocation in infant and monoblastic acute my...

    Authors: Katrin K. Fleischmann, Philipp Pagel, Julia von Frowein, Thomas Magg, Adelbert A. Roscher and Irene Schmid
    Citation: Journal of Experimental & Clinical Cancer Research 2016 35:9
  13. In spite of progress in diagnostics and treatment of Hepatocellular Carcinoma (HCC), its prognosis remains poor, and improved treatment strategies for HCC require detailed understanding of the underlying mecha...

    Authors: Lei Chang, Cuicui Li, Tao Guo, Haitao Wang, Weijie Ma, Yufeng Yuan, Quanyan Liu, Qifa Ye and Zhisu Liu
    Citation: Journal of Experimental & Clinical Cancer Research 2016 35:8
  14. Lung cancer has long been the most dangerous malignant tumor among males in both well developed and poorly developed countries. Radiotherapy plays a critical role in the curative management of inoperable non-s...

    Authors: Yiting Tang, Yayun Cui, Zengpeng Li, Zhuqing Jiao, Yong Zhang, Yan He, Guangxia Chen, Qunyan Zhou, Wenjie Wang, Xifa Zhou, Judong Luo and Shuyu Zhang
    Citation: Journal of Experimental & Clinical Cancer Research 2016 35:7

    The Erratum to this article has been published in Journal of Experimental & Clinical Cancer Research 2016 35:20

  15. While treatment failure in cases of head and neck squamous cell carcinoma (HNSCC) frequently takes the form of locoregional recurrences and distant metastasis, our understanding of the mechanisms of metastasis...

    Authors: Hiroshi Hyakusoku, Daisuke Sano, Hideaki Takahashi, Takashi Hatano, Yasuhiro Isono, Shoko Shimada, Yusuke Ito, Jeffrey N. Myers and Nobuhiko Oridate
    Citation: Journal of Experimental & Clinical Cancer Research 2016 35:6
  16. Grb2-associated binder 2 (Gab2), a scaffolding adaptor protein, has recently been implicated in cancer progression. However, the role of Gab2 in the progression and metastasis of colorectal cancer (CRC) remain...

    Authors: Chenbo Ding, Junmin Luo, Longmei Li, Shanshan Li, Liwen Yang, Hongfei Pan, Qianyi Liu, Huan Qin, Chao Chen and Jihong Feng
    Citation: Journal of Experimental & Clinical Cancer Research 2016 35:5
  17. Pigment epithelium-derived factor (PEDF) is a secreted glycoprotein and a non-inhibitory member of the serine protease inhibitor (serpin) family. It is widely expressed in human fetal and adult tissues but its...

    Authors: Louiza Belkacemi and Shaun Xiaoliu Zhang
    Citation: Journal of Experimental & Clinical Cancer Research 2016 35:4
  18. The synthetic biology technology which enhances the specificity and efficacy of treatment is a novel try in biomedical therapy during recent years. A high frequency of somatic mutations was shown in the human ...

    Authors: Li Liu, Yuchen Liu, Tianbiao Zhang, Hanwei Wu, Muqi Lin, Chaoliang Wang, Yonghao Zhan, Qing Zhou, Baoping Qiao, Xiaojuan Sun, Qiaoxia Zhang, Xiaoqiang Guo, Guoping Zhao, Weixing Zhang and Weiren Huang
    Citation: Journal of Experimental & Clinical Cancer Research 2016 35:3
  19. Maspin, a non-inhibitory member of the serine protease inhibitor superfamily, has been characterized as a tumor suppressor gene in multiple cancer types. Chemotherapeutic insensitivity is one of major obstacle...

    Authors: Jinbo Chen, Long Wang, Yunhua Tang, Guanghui Gong, Longfei Liu, Minfeng Chen, Zhi Chen, Yu Cui, Chao Li, Xu Cheng, Lin Qi and Xiongbing Zu
    Citation: Journal of Experimental & Clinical Cancer Research 2016 35:2
  20. Despite the global decline in the incidence and mortality of gastric cancer, it remains one of the most common malignant tumors of the digestive system. Although surgical resection is the preferred treatment f...

    Authors: Wenting Xu, Zhen Yang and Nonghua Lu
    Citation: Journal of Experimental & Clinical Cancer Research 2016 35:1
  21. Previously, we reported that polyploid giant cancer cells (PGCCs) induced by cobalt chloride (CoCl2) could have generated daughter cells with strong invasiveness and migration capabilities via asymmetric division...

    Authors: Fei Fei, Dan Zhang, Zhengduo Yang, Shujing Wang, Xian Wang, Zhengsheng Wu, Qiang Wu and Shiwu Zhang
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:158
  22. Overexpression of Metastasis-associated protein 1 (MTA1) in various cancer cells promotes tumor invasion and migration and predicts cancer patients’ poor prognosis. The pilot RNA-Seq data from our laboratory i...

    Authors: Ning Zhou, Haijuan Wang, Hongxu Liu, Hongsheng Xue, Feng Lin, Xiting Meng, Ailing Liang, Zhilong Zhao, YongJun Liu and Haili Qian
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:157
  23. After progression to a standard first-line platinum and gemcitabine combination (GP), there is no established second-line therapy for patients with advanced biliary tract cancers (aBTC). Indeed, literature dat...

    Authors: Lorenzo Fornaro, Caterina Vivaldi, Stefano Cereda, Francesco Leone, Giuseppe Aprile, Sara Lonardi, Nicola Silvestris, Daniele Santini, Michele Milella, Chiara Caparello, Gianna Musettini, Giulia Pasquini, Alfredo Falcone, Giovanni Brandi, Isabella Sperduti and Enrico Vasile
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:156
  24. Nanocapsules, as a delivery system, are able to target drugs and other biologically sensitive molecules to specific cells or organs. This system has been intensively investigated as a way to protect bioactives...

    Authors: Jérôme Roy, Liliam Teixeira Oliveira, Camille Oger, Jean-Marie Galano, Valerie Bultel-Poncé, Sylvain Richard, Andrea Grabe Guimaraes, José Mário Carneiro Vilela, Margareth Spangler Andrade, Thierry Durand, Pierre Besson, Vanessa Carla Furtado Mosqueira and Jean-Yves Le Guennec
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:155
  25. Lung cancer is the most common cause of cancer-related deaths worldwide. Natural phytochemicals from traditional medicinal plants such as solamargine have been shown to have anticancer properties. The prostagl...

    Authors: YuQing Chen, Qing Tang, JingJing Wu, Fang Zheng, LiJun Yang and Swei Sunny Hann
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:154
  26. Oncolytic virus which arms the therapeutic gene to enhance anti-tumor activity is a prevalent strategy to improve oncovirotherapy of cancer. Newcastle disease virus (NDV) is a naturally oncolytic virus used fo...

    Authors: Ding Wei, Qian Li, Xi-Long Wang, Yuan Wang, Jing Xu, Fei Feng, Gang Nan, Bin Wang, Can Li, Ting Guo, Zhi-Nan Chen and Huijie Bian
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:153
  27. Many promising anticancer molecules are abandoned during the course from bench to bedside due to lack of clear-cut efficiency and/or severe side effects. Vitamin K3 (vitK3) is a synthetic naphthoquinone exhibi...

    Authors: Tiantian He, Elie Hatem, Laurence Vernis, Ming Lei and Meng-Er Huang
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:152
  28. Metastasis-associated gene 1(MTA1) has been identified as an oncogene in many tumors, and aberrant MTA1 expression has been linked to carcinogenesis and metastasis. We aim to investigate the mechanism of MTA1 ...

    Authors: Caihua Xu, Fei Hua, Yihuan Chen, Haoyue Huang, Wenxue Ye, Yunsheng Yu and Zhenya Shen
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:151
  29. Patients diagnosed with melanoma brain metastases have few treatment options and poor prognosis, and improved treatment strategies for these patients require detailed understanding of the underlying pathobiolo...

    Authors: Trude G. Simonsen, Jon-Vidar Gaustad and Einar K. Rofstad
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:150
  30. Hematologic toxicity represents a major side effect of cytotoxic chemotherapy frequently preventing adequately dosed chemotherapy application and impeding therapeutic success. Transgenic (over)expression of ch...

    Authors: Sebastian Brennig, Nico Lachmann, Theresa Buchegger, Miriam Hetzel, Axel Schambach and Thomas Moritz
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:148
  31. Natural compounds have been demonstrated to lower breast cancer risk and sensitize tumor cells to anticancer therapies. Recently, we demonstrated that vernodalin (the active constituent of the medicinal herb Cent...

    Authors: Suresh Kumar Ananda Sadagopan, Nooshin Mohebali, Chung Yeng Looi, Mohadeseh Hasanpourghadi, Ashok Kumar Pandurangan, Aditya Arya, Hamed Karimian and Mohd Rais Mustafa
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:147
  32. The incidence of thyroid cancer has progressively increased over the past few decades, and the most frequent types of this cancer are papillary thyroid carcinoma (PTC) and small primary tumors. In PTC, oncogen...

    Authors: Shuiying Zhao, Qingzhu Wang, Zhizhen Li, Xiaojun Ma, Lina Wu, Hongfei Ji and Guijun Qin
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:146
  33. Karyopherin alpha 2 (KPNA2), a member of the karyopherin family, plays a vital role in carcinogenesis. Yet its role in colon cancer is poorly characterized. We sought to clarify the clinical significance of it...

    Authors: Yu Zhang, Meng Zhang, Fudong Yu, Su Lu, Huimin Sun, Huamei Tang and Zhihai Peng
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:145
  34. Tumour heterogeneity and resistance to systemic treatment in urothelial carcinoma (UC) may arise from cancer stem cells (CSC). A recent model describes cellular differentiation states within UC based on corres...

    Authors: Margaretha A. Skowron, Günter Niegisch, Gerhard Fritz, Tanja Arent, Joep G. H. van Roermund, Andrea Romano, Peter Albers, Wolfgang A. Schulz and Michèle J. Hoffmann
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:144
  35. Protein kinase A (PKA) is a holoenzyme that consists of a dimer of regulatory subunits and two inactive catalytic subunits that bind to the regulatory subunit dimer. Four regulatory subunits (RIα, RIβ, RIIα, R...

    Authors: Emmanouil Saloustros, Paraskevi Salpea, Chen-Feng Qi, Lina A. Gugliotti, Kitman Tsang, Sisi Liu, Matthew F. Starost, Herbert C. Morse III and Constantine A. Stratakis
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:143
  36. Colorectal cancer (CRC) ranks third among the estimated cancer cases and cancer related mortalities in the Western world. Early detection and efficient therapy of CRC remains a major health challenge. Therefor...

    Authors: Nirmala Jagadish, Deepak Parashar, Namita Gupta, Sumit Agarwal, Sapna Purohit, Vikash Kumar, Aditi Sharma, Rukhsar Fatima, Amos Prashant Topno, Chandrima Shaha and Anil Suri
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:142
  37. PD-L1 expression on neutrophils contributes to the impaired immune response in infectious disease, but the detailed role of PD-L1 expression on neutrophils in HCC remains unclear.

    Authors: Gaixia He, Henghui Zhang, Jinxue Zhou, Beibei Wang, Yanhui Chen, Yaxian Kong, Xingwang Xie, Xueyan Wang, Ran Fei, Lai Wei, Hongsong Chen and Hui Zeng
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:141
  38. Hepatitis C Virus (HCV) infection is associated with chronically evolving disease and development of hepatocellular carcinoma (HCC), albeit the mechanism of HCC induction by HCV is still controversial. The nuc...

    Authors: Anna Maria Mileo, Stefano Mattarocci, Paola Matarrese, Simona Anticoli, Claudia Abbruzzese, Stefania Catone, Rodolfo Sacco, Marco G. Paggi and Anna Ruggieri
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:140
  39. The receptor tyrosine kinase-like orphan receptors (ROR) family contains the atypical member ROR1, which plays an oncogenic role in several malignant tumors. However, the clinical potentials and underlying mec...

    Authors: Jinqiu Tao, Xiaofei Zhi, Xiaoyu Zhang, Min Fu, Hao Huang, Yu Fan, Wenxian Guan and Chen Zou
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:139
  40. Tumor progression locus 2 (TPL2), a serine-threonine kinase, functions as a critical regulator of inflammatory pathways and mediates oncogenic events. The potential role of Tpl2 in nonalcoholic fatty liver diseas...

    Authors: Xinli Li, Chun Liu, Blanche C. Ip, Kang-Quan Hu, Donald E. Smith, Andrew S. Greenberg and Xiang-Dong Wang
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:138
  41. Breast cancer is the most fatal malignant cancer among women, the conventional therapeutic modalities of it are limited. Morusin possesses cytotoxicity against some cancer cells in vitro. The purpose of this s...

    Authors: Haiyan Li, Qiaoping Wang, Lihua Dong, Chuanlan Liu, Zhen Sun, Ling Gao and Xiujie Wang
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:137
  42. Tumor-positive sentinel node(SLN) biopsy results in a risk of nonsentinel node metastases in case of micro and macro metastases ranging from 20 to 50 %, respectively. Therefore, most patients underwent unneces...

    Authors: F. Di Filippo, D. Giannarelli, C. Bouteille, L. Bernet, R. Cano, G. Cunnick and A. Sapino
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:136
  43. Linc00152 has been identified highly associated with the tumorigenesis and development of gastric cancer, however, the detailed mechanism of Linc00152 involved still remains unclear.

    Authors: Jianping Zhou, Xiaofei Zhi, Linjun Wang, Weizhi Wang, Zheng Li, Jie Tang, Jiwei Wang, Qun Zhang and Zekuan Xu
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:135

    The Erratum to this article has been published in Journal of Experimental & Clinical Cancer Research 2016 35:30

  44. Enhanced signalling via the epidermal growth factor receptor (EGFR) is a hallmark of multiple human carcinomas. However, in recent years data have accumulated that EGFR might also be hyperactivated in human sa...

    Authors: Florian Sevelda, Lisa Mayr, Bernd Kubista, Daniela Lötsch, Sushilla van Schoonhoven, Reinhard Windhager, Christine Pirker, Michael Micksche and Walter Berger
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:134
  45. Hepatocellular carcinoma (HCC) is a common malignant tumor that severely threatens human health. The poor prognosis of HCC is mainly attributed to intrahepatic and extrahepatic metastases. HOXD9 proteins belon...

    Authors: Xiupeng Lv, Linlin Li, Li Lv, Xiaotong Qu, Shi Jin, Kejun Li, Xiaoqin Deng, Lei Cheng, Hui He and Lei Dong
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:133
  46. Unresectable gastric cancer is associated with poor outcomes, with few treatment options available after failure of cytotoxic chemotherapy. Clinical trials of targeted therapies have generally shown no surviva...

    Authors: Hung Huynh, Richard Ong and Dieter Zopf
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:132
  47. Transcript dosage imbalance may influence the transcriptome. To gain insight into the role of altered gene expression in hereditary colorectal polyposis predisposition, in the present study we analyzed absolut...

    Authors: Gitana Maria Aceto, Fabiana Fantini, Sabrina De Iure, Marta Di Nicola, Giandomenico Palka, Rosa Valanzano, Patrizia Di Gregorio, Vittoria Stigliano, Maurizio Genuardi, Pasquale Battista, Alessandro Cama and Maria Cristina Curia
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:131
  48. Although expression of MTA1 inversely correlates with the nuclear localization of ERα, the effect and molecular mechanism of ERα regulation of MTA1 remain unknown.

    Authors: Lei Deng, Hui Yang, Junwei Tang, Zhe Lin, Aihong Yin, Yun Gao, Xuehao Wang, Runqiu Jiang and Beicheng Sun
    Citation: Journal of Experimental & Clinical Cancer Research 2015 34:128

Annual Journal Metrics

  • 2022 Citation Impact
    11.3 - 2-year Impact Factor
    11.5 - 5-year Impact Factor
    1.870 - SNIP (Source Normalized Impact per Paper)
    2.413 - SJR (SCImago Journal Rank)

    2023 Speed
    4 days submission to first editorial decision for all manuscripts (Median)
    100 days submission to accept (Median)

    2023 Usage 
    3,003,080 downloads
    3,022 Altmetric mentions