Skip to main content

Articles

Page 6 of 67

  1. Circular RNAs (circRNAs) play an important role in the progression of non-small cell lung cancer (NSCLC), especially under tumor hypoxia. However, the precise functions and underlying mechanisms of dysregulate...

    Authors: Dong Wu, Tingting Chen, Xuanna Zhao, Dan Huang, Jiawei Huang, Yujie Huang, Qiu Huang, Zhu Liang, Chunyuan Chen, Min Chen, Dongming Li, Bin Wu and Lixia Li
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:156
    Content type: Research Published on:

  2. The overall response rate to checkpoint blockade remains unsatisfactory, partially due to the immune-suppressive tumor microenvironment. A retinoic acid-related orphan receptor γt (RORγt) agonist (LYC-55716) i...

    Authors: Li Xia, Enming Tian, Mingcheng Yu, Chenglong Liu, Lian Shen, Yafei Huang, Zhongen Wu, Jinlong Tian, Ker Yu, Yonghui Wang, Qiong Xie and Di Zhu
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:155
    Content type: Research Published on:

  3. Osteosarcoma (OS) is a malignant bone tumor mostly occurring in children and adolescents, while chemotherapy resistance often develops and the mechanisms involved remain challenging to be fully investigated.

    Authors: Mingrui Du, Jintao Gu, Chenlin Liu, Nannan Liu, Zhe Yu, Chengpei Zhou, Wei Heng, Zhengcong Cao, Feilong Wei, Kailong Zhu, Yingwen Wang, Wei Zhang, Xiaochang Xue, Yong Zhang and Jixian Qian
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:154
    Content type: Research Published on:

  4. Chemoresistance of pancreatic cancer is the main reason for the poor treatment effect of pancreatic cancer patients. Exploring chemotherapy resistance-related genes has been a difficult and hot topic of oncolo...

    Authors: Zhi-Wen Chen, Jian-Fei Hu, Zu-Wei Wang, Cheng-Yu Liao, Feng-Ping Kang, Cai-Feng Lin, Yi Huang, Long Huang, Yi-Feng Tian and Shi Chen
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:153
    Content type: Research Published on:

  5. Extracellular vesicles (EVs) derived from tumor-associated macrophages are implicated in the progression and metastasis of gastric cancer (GC) via the transfer of molecular cargo RNAs. We aimed to decipher the...

    Authors: Yi Cao, Yi Tu, Jianbo Xiong, Shengxing Tan, Lianghua Luo, Ahao Wu, Xufeng Shu, Zhigang Jie and Zhengrong Li
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:152
    Content type: Research Published on:

  6. Cancer mortality is mainly caused by organ failure and thrombotic events. It has been demonstrated that NETosis, a chromatin release mechanism implemented by neutrophils, may contribute to these lethal systemi...

    Authors: Livia Ronchetti, Irene Terrenato, Margherita Ferretti, Giacomo Corrado, Frauke Goeman, Sara Donzelli, Chiara Mandoj, Roberta Merola, Ashanti Zampa, Mariantonia Carosi, Giovanni Blandino, Laura Conti, Anna Maria Lobascio, Marcello Iacobelli, Enrico Vizza, Giulia Piaggio…
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:151
    Content type: Research Published on:

  7. Oral squamous cell carcinoma (OSCC) is one of the common cancers worldwide. The lack of specific biomarkers and therapeutic targets leads to delayed diagnosis and hence the poor prognosis of OSCC patients. Thu...

    Authors: Yan Dong, Liyan Xue, Yan Zhang, Caiyun Liu, Yanguang Zhang, Na Jiang, Xiaoyan Ma, Fangyu Chen, Lingxia Li, Liyuan Yu, Xuefeng Liu, Shujuan Shao, Shufang Guan, Jian Zhang, Qingchun Xiao, Hui Li…
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:150
    Content type: Research Published on:

  8. Cyclin-dependent kinase 16 (CDK16) is an atypical PCTAIRE kinase, and its activity is dependent on the Cyclin Y (CCNY) family. Ccnys have been reported to regulate mammary stem cell activity and mammary gland ...

    Authors: Xiao Li, Jinpeng Li, Liming Xu, Wei Wei, Anyi Cheng, Lingxian Zhang, Mengna Zhang, Gaosong Wu and Cheguo Cai
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:149
    Content type: Research Published on:

  9. Despite the promise of dual BRAF/MEK inhibition as a therapy for BRAF-mutant (BRAF-mut) melanoma, heterogeneous responses have been observed in patients, thus predictors of benefit from therapy are needed. We ...

    Authors: Rossella Loria, Valentina Laquintana, Stefano Scalera, Rocco Fraioli, Valentina Caprara, Italia Falcone, Chiara Bazzichetto, Marta Di Martile, Laura Rosanò, Donatella Del Bufalo, Gianluca Bossi, Isabella Sperduti, Irene Terrenato, Paolo Visca, Silvia Soddu, Michele Milella…
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:148
    Content type: Research Published on:

  10. Authors: Liling Wen, Huanzi Lu, Qiusheng Li, Qunxing Li, Shuqiong Wen, Dikan Wang, Xi Wang, Juan Fang, Jun Cui, Bin Cheng and Zhi Wang
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:147
    Content type: Correction Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2019 38:299

  11. Despite recent advances in radiotherapy, radioresistance in patients with pancreatic cancer remains a crucial dilemma for clinical treatment. Cancer stem cells (CSCs) represent a major factor in radioresistanc...

    Authors: Mohammed Salah, Hiroaki Akasaka, Yasuyuki Shimizu, Kenta Morita, Yuya Nishimura, Hikaru Kubota, Hiroki Kawaguchi, Tomomi Sogawa, Naritoshi Mukumoto, Chiaki Ogino and Ryohei Sasaki
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:146
    Content type: Research Published on:

  12. Metastasis is the leading cause of mortality in human cancers, including esophageal squamous cell carcinoma (ESCC). As a pro-inflammatory cytokine, IL-32 was reported to be a poor prognostic factor in many can...

    Authors: Yixuan Sun, Yuzhen Qian, Chunxia Chen, Hongfei Wang, Xiuman Zhou, Wenjie Zhai, Lu Qiu, Xiaowen Zhou, Haoming Ning, Yumiao Zhao, Chao Shi, Lu Han, Yuanming Qi, Yahong Wu and Yanfeng Gao
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:145
    Content type: Research Published on:

  13. Metabolites are intermediate products of cellular metabolism catalysed by various enzymes. Metabolic remodelling, as a biochemical fingerprint of cancer cells, causes abnormal metabolite accumulation. These me...

    Authors: Yidian Fu, Jie Yu, Fang Li and Shengfang Ge
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:144
    Content type: Review Published on:

  14. Cancer cells can evade immune responses by exploiting inhibitory immune checkpoints. Immune checkpoint inhibitor (ICI) therapies based on anti-CTLA-4 and anti-PD-1/PD-L1 antibodies have been extensively explor...

    Authors: Andreia Peixoto, Andreia Miranda, Lúcio Lara Santos and José Alexandre Ferreira
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:143
    Content type: Review Published on:

  16. Challenges exist in the clinical treatment of luminal estrogen receptor α (ERα)-positive breast cancers (BCs) both to prevent resistance to endocrine therapy (ET) and to treat ET-resistant metastatic BCs (MBC)...

    Authors: Sara Pescatori, Stefano Leone, Manuela Cipolletti, Stefania Bartoloni, Alessandra di Masi and Filippo Acconcia
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:141
    Content type: Research Published on:

  17. Selectively utilizing alternative mechanisms to repair damaged DNA in essential factors deficient cancer facilitates tumor genetic evolution and contributes to treatment resistance. Synthetic lethality strateg...

    Authors: Jing Zhang, Mu Chen, Ying Pang, Meng Cheng, Bingsong Huang, Siyi Xu, Min Liu, Hao Lian and Chunlong Zhong
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:140
    Content type: Research Published on:

  18. Glioblastoma multiforme (GBM) is an incurable tumor, with a median survival rate of only 14–15 months. Along with heterogeneity and unregulated growth, a central matter in dealing with GBMs is cell invasivenes...

    Authors: Nadia Trivieri, Alberto Visioli, Gandino Mencarelli, Maria Grazia Cariglia, Laura Marongiu, Riccardo Pracella, Fabrizio Giani, Amata Amy Soriano, Chiara Barile, Laura Cajola, Massimiliano Copetti, Orazio Palumbo, Federico Legnani, Francesco DiMeco, Leonardo Gorgoglione, Angelo L. Vescovi…
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:139
    Content type: Research Published on:

  19. Authors: Maria Serena Roca, Tania Moccia, Federica Iannelli, Cristina Testa, Carlo Vitagliano, Michele Minopoli, Rosa Camerlingo, Giulia De Riso, Rossella De Cecio, Francesca Bruzzese, Mariarosaria Conte, Lucia Altucci, Elena Di Gennaro, Antonio Avallone, Alessandra Leone and Alfredo Budillon
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:138
    Content type: Correction Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2022 41:83

  20. Pancreatic ductal adenocarcinoma (PDAC) is the most common pancreatic neoplasm with high metastatic potential and poor clinical outcome. Like other solid tumors, PDAC in the early stages is often asymptomatic,...

    Authors: Tzu-Chin Wu, Chien-Yu Liao, Wei-Chien Lu, Chuang-Rung Chang, Fang-Yu Tsai, Shih-Sheng Jiang, Tsung-Hsien Chen, Kurt Ming-Chao Lin, Li-Tzong Chen and Wun-Shaing Wayne Chang
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:137
    Content type: Research Published on:

  21. Extracellular vesicles (EVs) are emerging mediators of intercellular communication that have been shown to play important roles in tumor progression. YRNA fragments, a type of small non-coding RNA, are dysregu...

    Authors: Chuang Li, Wei Wang, Yuting Sun, Yifan Ni, Fang Qin, Xiaolu Li, Tao Wang, Mingxiong Guo and Guihong Sun
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:136
    Content type: Research Published on:

  22. The TANK-binding kinase 1 (TBK1) is a serine/threonine kinase belonging to the non-canonical inhibitor of nuclear factor-κB (IκB) kinase (IKK) family. TBK1 can be activated by pathogen-associated molecular pat...

    Authors: Austin P. Runde, Ryan Mack, Peter Breslin S.J. and Jiwang Zhang
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:135
    Content type: Review Published on:

  23. This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s13046-021-01973-z.

    Authors: Lin-pei Wang, Jing Lin, Xiao-qiu Ma, Dong-yao Xu, Chun-feng Shi, Wei Wang and Xiao-jie Jiang
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:134
    Content type: Retraction Note Published on:

  24. Cancer stem-like cells (CSCs) play a pivotal role in lung tumor formation and progression. Nerve injury-induced protein 1 (Ninjurin1, Ninj1) has been implicated in lung cancer; however, the pathological role o...

    Authors: Seung Yeob Hyun, Hye-Young Min, Ho Jin Lee, Jaebeom Cho, Hye-Jin Boo, Myungkyung Noh, Hyun-Ji Jang, Hyo-Jong Lee, Choon-Sik Park, Jong-Sook Park, Young Kee Shin and Ho-Young Lee
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:133
    Content type: Research Published on:

  25. Interactions between tumor and microenvironment determine individual response to immunotherapy. Triple negative breast cancer (TNBC) and hepatocellular carcinoma (HCC) have exhibited suboptimal responses to im...

    Authors: Xuewei Bai, Yanmei Zhou, Yuki Yokota, Yoshihiro Matsumoto, Bo Zhai, Nader Maarouf, Hikaru Hayashi, Rolf Carlson, Songhua Zhang, Aryanna Sousa, Bei Sun, Hossein Ghanbari, Xiaoqun Dong and Jack R. Wands
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:132
    Content type: Research Published on:

  26. Hypoxia is a hallmark of the tumor microenvironment (TME) and in addition to altering metabolism in cancer cells, it transforms tumor-associated stromal cells. Within the tumor stromal cell compartment, tumor-...

    Authors: Khiyam Hussain, Rena Liu, Rosanna C. G. Smith, Kri T. J. Müller, Mohammadmersad Ghorbani, Sofia Macari, Kirstie L. S. Cleary, Robert J. Oldham, Russell B. Foxall, Sonya James, Steven G. Booth, Tom Murray, Lekh N. Dahal, Chantal E. Hargreaves, Robert S. Kemp, Jemma Longley…
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:131
    Content type: Research Published on:

  27. Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancer due to its highly aggressive phenotype and lack of effective biomarkers or treatment strategies. ZMAT1 belongs to the C2H2 type zinc finge...

    Authors: Zuyi Ma, Zhenchong Li, Shujie Wang, Zixuan Zhou, Chunsheng Liu, Hongkai Zhuang, Qi Zhou, Shanzhou Huang, Chuanzhao Zhang and Baohua Hou
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:130
    Content type: Research Published on:

  28. Stanniocalcin 1 (STC1) plays an integral role in ovarian cancer (OC). However, the functional role of STC1 in metastasis, lipid metabolism and cisplatin (DDP) chemoresistance in OC is not fully understood.

    Authors: Feikai Lin, Xiaoduan Li, Xinjing Wang, Huizhen Sun, Ziliang Wang and Xipeng Wang
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:129
    Content type: Research Published on:

  29. Radiation-induced lung fibrosis (RILF) is a common complication of thoracic radiotherapy. Alveolar epithelial cells play a crucial role in lung fibrosis via epithelial-mesenchymal transition (EMT). Exosomes de...

    Authors: Yi Li, Zhufu Shen, Xiao Jiang, Yuanyuan Wang, Zuozhang Yang, Yuchi Mao, Zhixian Wu, Gaofeng Li and Hong Chen
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:128
    Content type: Research Published on:

  30. Cholangiocarcinoma (CCA) is the second most common primary liver cancer and associated with a dismal prognosis due to the lack of an efficient systemic therapy. In contrast to other cancers, new immunotherapie...

    Authors: Dong Liu, Lara Rosaline Heij, Zoltan Czigany, Edgar Dahl, Sven Arke Lang, Tom Florian Ulmer, Tom Luedde, Ulf Peter Neumann and Jan Bednarsch
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:127
    Content type: Review Published on:

  31. Compared to normal cells, cancer cells exhibit a higher level of oxidative stress, which primes key cellular and metabolic pathways and thereby increases their resilience under oxidative stress. This higher le...

    Authors: Jing Cui, Jingcheng Zhou, Weiqing He, Juan Ye, Timothy Westlake, Rogelio Medina, Herui Wang, Bhushan L. Thakur, Juanjuan Liu, Mingyu Xia, Zhonggui He, Fred E. Indig, Aiguo Li, Yan Li, Robert J. Weil, Mirit I. Aladjem…
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:126
    Content type: Research Published on:

  32. The development of castration-resistant prostate cancer (CRPC) remains a major obstacle in the treatment of prostate cancer (PCa). Dysregulated mitochondrial function has been linked to the initiation and prog...

    Authors: Ru Zhao, Tingting Feng, Lin Gao, Feifei Sun, Qianqian Zhou, Xin Wang, Junmei Liu, Wenbo Zhang, Meng Wang, Xueting Xiong, Wenqiao Jia, Weiwen Chen, Lin Wang and Bo Han
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:125
    Content type: Research Published on:

  33. Authors: Fei Zhang, Qiang Ma, Zihang Xu, Haibin Liang, Huaifeng Li, Yuanyuan Ye, Shanshan Xiang, Yijian Zhang, Lin Jiang, Yunping Hu, Zheng Wang, Xuefeng Wang, Yong Zhang, Wei Gong and Yingbin Liu
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:124
    Content type: Correction Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2017 36:68

  34. While immune checkpoint inhibitors (ICI) were approved for head and neck squamous cell carcinomas (HNSCCs), the response rate remains relatively low. Mechanisms underlying ICI unresponsiveness versus sensitivi...

    Authors: Samantha M. Y. Chen, Vince Popolizio, Rachel A. Woolaver, Huaibin Ge, Alexandra L. Krinsky, Jessy John, Etienne Danis, Yao Ke, Yonatan Kramer, Li Bian, Andrew G. Nicklawsky, Dexiang Gao, Silvia Liu, Zhangguo Chen, Xiao-jing Wang and Jing H. Wang
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:123
    Content type: Research Published on:

  35. Hypoxic tumor microenvironment (TME) contributes to the onset of many aspects of the cancer biology associated to the resistance to conventional therapies. Hypoxia is a common characteristic and negative progn...

    Authors: Annachiara Sarnella, Ylenia Ferrara, Luigi Auletta, Sandra Albanese, Laura Cerchia, Vincenzo Alterio, Giuseppina De Simone, Claudiu T. Supuran and Antonella Zannetti
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:122
    Content type: Research Published on:

  36. This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s13046-019-1239-3.

    Authors: Dong-Mei Wu, Zi-Hui Zheng, Ying-Bo Zhang, Shao-Hua Fan, Zi-Feng Zhang, Yong-Jian Wang, Yuan-Lin Zheng and Jun Lu
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:121
    Content type: Retraction Note Published on:

  37. Circular RNA (circRNA) has been recently identified as a critical regulator during carcinogenesis. However, the biological function and potential underlying mechanisms of circRNAs in lung cancer remain to be f...

    Authors: Dongni Chen, Hongli Zhou, Zhuochen Cai, Kaican Cai, Ji Liu, Weidong Wang, Huikai Miao, Hongmu Li, Rongzhen Li, Xiaodong Li, Youfang Chen, Hui-Yun Wang and Zhesheng Wen
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:120
    Content type: Research Published on:

  38. Adoptive cell therapy with chimeric antigen receptor (CAR) immunotherapy has made tremendous progress with five CAR T therapies approved by the US Food and Drug Administration for hematological malignancies. H...

    Authors: Kevin Pan, Hizra Farrukh, Veera Chandra Sekhar Reddy Chittepu, Huihong Xu, Chong-xian Pan and Zheng Zhu
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:119
    Content type: Review Published on:

  39. Authors: Neng Wang, Qi Wang, Hailin Tang, Fengxue Zhang, Yifeng Zheng, Shengqi Wang, Jin Zhang, Zhiyu Wang and Xiaoming Xie
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:118
    Content type: Correction Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2017 36:172

  40. Authors: Xiaoqing Sun, Zhenyu He, Ling Guo, Caiqin Wang, Chuyong Lin, Liping Ye, Xiaoqing Wang, Yue Li, Meisongzhu Yang, Sailan Liu, Xin Hua, Wen Wen, Chao Lin, Zhiqing Long, Wenwen Zhang, Han Li…
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:117
    Content type: Correction Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2021 40:149

  41. Hepatocellular carcinoma (HCC) is one of the most malignant tumors and the fourth leading cause of cancer-related death worldwide. Sorafenib is currently acknowledged as a standard therapy for advanced HCC. Ho...

    Authors: Danyang Li, Yingcheng Yao, Yuhan Rao, Xinyu Huang, Li Wei, Zhimei You, Guo Zheng, Xiaoli Hou, Yu Su, Zac Varghese, John F. Moorhead, Yaxi Chen and Xiong Z. Ruan
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:116
    Content type: Research Published on:

  42. The inhibition of neddylation by the preclinical drug MLN4924 represents a new strategy to combat cancer. However, despite being effective against hematologic malignancies, its success in solid tumors, where c...

    Authors: Frédérique Mittler, Patricia Obeïd, Vincent Haguet, Cédric Allier, Sophie Gerbaud, Anastasia V. Rulina, Xavier Gidrol and Maxim Y. Balakirev
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:115
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Experimental & Clinical Cancer Research 2022 41:167

  43. This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s13046-020-01594-y.

    Authors: Chen Chen, Zhiguo Huang, Xiaoye Mo, Yanmin Song, Xiangmin Li, Xiaogang Li and Mu Zhang
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:114
    Content type: Retraction Note Published on:

  44. In the last years, several efforts have been made to classify colorectal cancer (CRC) into well-defined molecular subgroups, representing the intrinsic inter-patient heterogeneity, known as Consensus Molecular...

    Authors: Martina Mazzeschi, Michela Sgarzi, Donatella Romaniello, Valerio Gelfo, Carola Cavallo, Francesca Ambrosi, Alessandra Morselli, Carmen Miano, Noemi Laprovitera, Cinzia Girone, Manuela Ferracin, Spartaco Santi, Karim Rihawi, Andrea Ardizzoni, Michelangelo Fiorentino, Gabriele D’Uva…
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:113
    Content type: Research Published on:

  45. The tyrosine kinase receptor encoded by the MET oncogene is a major player in cancer. When MET is responsible for the onset and progression of the transformed phenotype (MET-addicted cancers), an efficient blo...

    Authors: Ilaria Martinelli, Chiara Modica, Cristina Chiriaco, Cristina Basilico, James M. Hughes, Simona Corso, Silvia Giordano, Paolo M. Comoglio and Elisa Vigna
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:112
    Content type: Research Published on:

    The Correction to this article has been published in Journal of Experimental & Clinical Cancer Research 2022 41:180

  46. Emerging evidence has demonstrated that RNA-binding protein dysregulation is involved in esophageal squamous cell carcinoma (ESCC) progression. However, the role of poly (A) binding protein cytoplasmic 1 (PABP...

    Authors: Ying Zhang, Chuangzhen Chen, Zhaoyong Liu, Huancheng Guo, Weiqing Lu, Wang Hu and Zhixiong Lin
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:111
    Content type: Research Published on:

  47. CD44 is a multifunctional membrane glycoprotein. Through its heparan sulfate chain, CD44 presents growth factors to their receptors. We have shown that CD44 and Tropomyosin kinase A (TrkA) form a complex follo...

    Authors: Sarah Trouvilliez, Julien Cicero, Romain Lévêque, Léo Aubert, Cyril Corbet, Alexandre Van Outryve, Karolin Streule, Pierre-Olivier Angrand, Pamela Völkel, Romain Magnez, Guillaume Brysbaert, Caroline Mysiorek, Fabien Gosselet, Roland Bourette, Eric Adriaenssens, Xavier Thuru…
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:110
    Content type: Research Published on:

  48. We recently conducted Cetuximab-AVElumab-Lung (CAVE-Lung), a proof-of-concept, translational and clinical trial, to evaluate the combination of two IgG1 monoclonal antibodies (mAb): avelumab, an anti-PD-L1 dru...

    Authors: Carminia Maria Della Corte, Morena Fasano, Vincenza Ciaramella, Flora Cimmino, Robert Cardnell, Carl M. Gay, Kavya Ramkumar, Lixia Diao, Raimondo Di Liello, Giuseppe Viscardi, Vincenzo Famiglietti, Davide Ciardiello, Giulia Martini, Stefania Napolitano, Concetta Tuccillo, Teresa Troiani…
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:109
    Content type: Research Published on:

  49. Anaplastic Thyroid Cancer (ATC) is an undifferentiated and aggressive tumor that often originates from well-Differentiated Thyroid Carcinoma (DTC) through a trans-differentiation process. Epithelial-to-Mesench...

    Authors: Mila Gugnoni, Gloria Manzotti, Emanuele Vitale, Elisabetta Sauta, Federica Torricelli, Francesca Reggiani, Mariaelena Pistoni, Simonetta Piana and Alessia Ciarrocchi
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:108
    Content type: Research Published on:

  50. Hepatocellular carcinoma (HCC) is the most frequent primary liver cancer, being the sixth most commonly diagnosed cancer and the fourth leading cause of cancer-related death. As other heterogeneous solid tumou...

    Authors: Maria Rita Braghini, Oriana Lo Re, Ilaria Romito, Maite G. Fernandez-Barrena, Barbara Barbaro, Silvia Pomella, Rossella Rota, Manlio Vinciguerra, Matias A. Avila and Anna Alisi
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:107
    Content type: Review Published on:

Annual Journal Metrics

Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

Contact us