Owned by the Association for International Promotion & Study in Tumors (APSIT)
Retinoic acid and proteotoxic stress induce AML cell death overcoming stromal cell protection
Acute myeloid leukemia (AML) patients bearing the ITD mutation in the tyrosine kinase receptor FLT3 (FLT3-ITD) present a poor prognosis and a high risk of relapse. FLT3-ITD is retained in the endoplasmic retic...