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  1. The prognostic value of HER2 expression in patients with advanced non-small cell lung cancer remains controversial. The relationship between HER2 expression, and platinum resistance and patient survival, was i...

    Authors: Zuleyha Calikusu, Yesim Yildirim, Zafer Akcali, Hakan Sakalli, Nebil Bal, Ilker Unal and Ozgur Ozyilkan
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:97
  2. Resveratrol is a non flavonoid polyphenol compound present in many plants and fruits and, at especially high concentrations, in the grape berries of Vitis vinifera. This compound has a strong bioactivity and its ...

    Authors: Valerio Berardi, Francesca Ricci, Mauro Castelli, Gaspare Galati and Gianfranco Risuleo
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:96
  3. To compare intracavitary brachytherapy (ICBT) planning methods for cervical cancer, based on either orthogonal radiographs (conventional plan) or CT sections (CT plan); the comparison focused on target volume ...

    Authors: Cem Onal, Gungor Arslan, Erkan Topkan, Berrin Pehlivan, Melek Yavuz, Ezgi Oymak and Aydin Yavuz
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:95
  4. Some TGFB1 and VEGF polymorphisms are believed to be functional. Given that these genes are involved in tumor growth and progression including angiogenesis, dissemination, and invasiveness, we hypothesized that t...

    Authors: Xiaoxiang Guan, Hui Zhao, Jiangong Niu, Dongfeng Tan, Jaffer A Ajani and Qingyi Wei
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:94
  5. Selenite is a promising anticancer agent which has been shown to induce apoptosis in malignant mesothelioma cells in a phenotype-dependent manner, where cells of the chemoresistant sarcomatoid phenotype are mo...

    Authors: Gustav Nilsonne, Eric Olm, Adam Szulkin, Filip Mundt, Agnes Stein, Branka Kocic, Anna-Klara Rundlöf, Aristi P Fernandes, Mikael Björnstedt and Katalin Dobra
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:92
  6. Platinum-based neoadjuvant chemotherapy (NAC) is new therapeutic strategy for locally advanced cervical carcinoma, but the variables used to predict NAC response are still infrequently reported. The aim of our...

    Authors: Xiao-Dong Cheng, Wei-Guo Lu, Feng Ye, Xiao-Yun Wan and Xing Xie
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:91
  7. Type 2 diabetes (T2D) is associated with obesity and has been shown recently to be associated with tumors/cancer. HNF1-beta and JAZF1 genes are associated with T2D and prostate cancer. We have previously shown th...

    Authors: Ramachandran Meenakshisundaram, Nunzia Piumelli, Laura Pierpaoli and Claudia Gragnoli
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:90
  8. Lung cancer is the leading cause of death from cancer worldwide. Conventional studies mainly think that insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 (IGFBP-3) may promote and inhibit tumor gr...

    Authors: Bo Chen, Shan Liu, Wei Xu, Xueli Wang, Weihong Zhao and Jianqing Wu
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:89
  9. To show magnetic resonance imaging (MRI) texture appearance change in non-Hodgkin lymphoma (NHL) during treatment with response controlled by quantitative volume analysis.

    Authors: Lara CV Harrison, Tiina Luukkaala, Hannu Pertovaara, Tuomas O Saarinen, Tomi T Heinonen, Ritva Järvenpää, Seppo Soimakallio, Pirkko-Liisa I Kellokumpu-Lehtinen, Hannu J Eskola and Prasun Dastidar
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:87
  10. We aimed to determine the incidence of women's breast cancer in Italy without using statistical approximations.

    Authors: Prisco Piscitelli, Antonio Santoriello, Franco M Buonaguro, Massimo Di Maio, Giovanni Iolascon, Francesca Gimigliano, Alessandra Marinelli, Alessandro Distante, Giuseppe Serravezza, Emiliano Sordi, Katia Cagossi, Fabrizio Artioli, Michele Santangelo, Alfredo Fucito, Raffaele Gimigliano, Maria Luisa Brandi…
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:86
  11. No satisfactory biomarkers are currently available to screen for nasopharyngeal carcinoma (NPC). We have developed and evaluated surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (S...

    Authors: Yuan-Jiao Huang, Chao Xuan, Bei-Bei Zhang, Ming Liao, Kai-Feng Deng, Min He and Jin-Min Zhao
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:85
  12. Intracellular levels of zinc have shown a strong inverse correlation to growth and malignancy of prostate cancer. To date, studies of zinc supplementation in prostate cancer have been equivocal and have not ac...

    Authors: Maulik R Shah, Christopher L Kriedt, Nathan H Lents, Mary K Hoyer, Nimah Jamaluddin, Claudette Klein and Joseph Baldassare
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:84
  13. The aim of this study was to determine a predictive indicator of gemcitabine (GEM) efficacy in unresectable pancreatic cancer using tissue obtained by endoscopic ultrasound-guided fine-needle aspiration biopsy...

    Authors: Reiko Ashida, Bunzo Nakata, Minoru Shigekawa, Nobumasa Mizuno, Akira Sawaki, Kosei Hirakawa, Tetsuo Arakawa and Kenji Yamao
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:83
  14. MircoRNAs(miRNAs) are short, endogenously non-coding RNAs. The abnormal expression of miRNAs may be valuable for the diagnosis and treatment of tumors.

    Authors: Hongchun Luo, Hongbin Zhang, Zhenzhen Zhang, Xia Zhang, Bo Ning, Jinjun Guo, Na Nie, Bo Liu and Xiaoling Wu
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:82
  15. Colorectal cancer is a one of the most common alimentary malignancies. Survivin has been proved by many studies to be an ideal target for cancer gene therapy because of its strong anti-apoptotic effect. The re...

    Authors: Wei Shen, Chun-Yi Wang, Xue-Hu Wang and Zhong-Xue Fu
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:81
  16. The incidence of hepatocellular carcinoma is increasing in many countries. The estimated number of new cases annually is over 500,000, and the yearly incidence comprises between 2.5 and 7% of patients with liv...

    Authors: AlaaEddeen M Seufi, Safinz S Ibrahim, Tarek K Elmaghraby and Elsayed E Hafez
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:80
  17. FBG2 (F-BOX6) gene is an important member in ubiquitin metabolic system F-BOX family, and forms E3 complex with the other members in the family. But its role in gastric cancer is still not clear. In the presen...

    Authors: Lin Zhang, Yanhong Hou, Mengwei Wang, Benyan Wu and Nan Li
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:78
  18. opioid and somatostatin receptors (SSTRs) that can assemble as heterodimer were individually reported to modulate malignant cell proliferation and to favour apoptosis. Materials and methods: SSTRs and opioid r...

    Authors: Céline Kerros, Thibault Cavey, Brigitte Sola, Philippe Jauzac and Stéphane Allouche
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:77
  19. We observed that paclitaxel altered the pharmacokinetic properties of gemcitabine in patients with non-small cell lung cancer (NSCLC) and limited the accumulation of gemcitabine and its metabolites in various ...

    Authors: Stacy S Shord and Shitalben R Patel
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:76
  20. Angiogenesis plays an important role in tumor growth, invasion, and eventually metastasis. Antiangiogenic strategies have been proven to be a promising approach for clinical therapy for a variety of tumors. As...

    Authors: Li-Ping Yang, Ping Cheng, Xing-Chen Peng, Hua-Shan Shi, Wei-Hong He, Feng-Yu Cui, Shun-Tao Luo, Yu-Quan Wei and Li Yang
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:75
  21. Centromere protein H (CENP-H) is one of the fundamental components of the human active kinetochore. Recently, CENP-H was identified to be associated with tumorigenesis. This study was aimed to investigate the ...

    Authors: Wen-Ting Liao, Chun-Ping Yu, Dong-Hui Wu, Ling Zhang, Li-Hua Xu, Gui-Xiang Weng, Mu-Sheng Zeng, Li-Bing Song and Jin-Song Li
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:74
  22. Reactive oxygen species (ROS) are closely associated with the intracellular signal cascade, thus strongly implicating involvement in tumor progression. However, the mechanism by which ROS are generated and how...

    Authors: Kyung Hee Lee, Sang Woon Kim and Jae-Ryong Kim
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:73
  23. The relapse of cancer after radiotherapy is a clinical knotty problem. Previous studies have demonstrated that the elevation of several factors is likely in some way to lead to the development of treatment tol...

    Authors: Degang Shi, Genming Shi, Gang Huang, Jiren Zhang and Eric Lartigau
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:72
  24. Hepatocellular carcinoma (HCC) is a lethal malignancy with high rate of metastasis and poor prognosis. There are no effective managements to block metastasis of HCC. Programmed cell death 4 (PDCD4) is found to...

    Authors: Shuhong Zhang, Jianfeng Li, Ying Jiang, Yijun Xu and Chengyong Qin
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:71
  25. Insulin-like growth factor binding protein (IGFBPs) have been as potential tumor suppressors in the occurrence and development of tumors. Cellular Fas-associated death domain-like interleukin-1β-converting enz...

    Authors: Xue-Jing Hou, You-Zhong Zhang, Xin Liu, Li-Hua Meng and Yun-Bo Qiao
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:70
  26. Chemo-radiotherapy, a combination of chemotherapy and radiotherapy, is the most frequent treatment for patients with esophageal cancer. In the process of radiotherapy, the radiosensitive cancer will become a r...

    Authors: Li Xie, Xianrang Song, Jinming Yu, Ling Wei, Bao Song, Xingwu Wang and Liyan Lv
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:68
  27. The α6β4 integrin is overexpressed in the basal subtype of breast cancer and plays an important role in tumor cell motility and invasion. EGFR is also overexpressed in the basal subtype of breast cancer, and c...

    Authors: Michael Z Gilcrease, Xiao Zhou, Xiaolin Lu, Wendy A Woodward, Brian E Hall and Phillip J Morrissey
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:67
  28. Molecularly targeted agents for the treatment of solid tumors had entered the market in the last 5 years, with a great impact upon both the scientific community and the society. Many randomized phase III trial...

    Authors: Emilio Bria, Massimo Di Maio, Paolo Carlini, Federica Cuppone, Diana Giannarelli, Francesco Cognetti and Michele Milella
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:66
  29. An increasing number of studies have shown that ERK and PI3-K/AKT signaling pathways are involved in various human cancers including hepatocellular carcinoma and cholangiocarcinoma. However, few studies have e...

    Authors: Qinglong Li and Zhulin Yang
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:65
  30. Non-coding RNA molecules, such as microRNAs, may play an important role in carcinogenesis. Recent studies have indicated that microRNAs are involved in initiation and progression of various malignancies. Howev...

    Authors: Tao Yu, Xiao-yi Wang, Ren-guo Gong, An Li, Sen Yang, Yu-tang Cao, Yu-ming Wen, Chang-mei Wang and Xin-zhu Yi
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:64
  31. A novel multi-drug resistance gene named as HA117 has been screened and cloned in multidrug resisitant leukemia cell lines in our previous research, but its function is still unknown. In this study, HA117 gene...

    Authors: Yuxia Guo, Gaihuan Zheng, Xianqing Jin, Youhua Xu, Qing Luo, Xiaomei Liu, Zhenzhen Zhao and Yong Chen
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:63
  32. The pathogenesis of biliary cancers is ill-defined. This study investigates changes in gene expression and copy number in biliary cancers and correlates these changes with anatomical site of origin, histopatho...

    Authors: George Miller, Nicholas D Socci, Deepti Dhall, Michael D'Angelica, Ronald P DeMatteo, Peter J Allen, Bhuvanesh Singh, Yuman Fong, Leslie H Blumgart, David S Klimstra and William R Jarnagin
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:62
  33. Seizure control doesn't represent the only challenging goal in patients with brain tumor-related epilepsy. Side effects have often taken precedence for patients' quality of life.

    Authors: Marta Maschio, Loredana Dinapoli, Antonello Vidiri, Andrea Pace, Alessandra Fabi, Alfredo Pompili, Maria Carmine Carapella and Bruno Jandolo
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:60
  34. There are around 350 million of hepatitis B surface antigen (HBsAg) carriers worldwide, and among them, high risk of developing hepatocellular carcinoma (HCC) has been identified by epidemiological studies. To...

    Authors: Xiaochen Tian, Jinjun Li, Zhang-Mei Ma, Chao Zhao, Da-Fang Wan and Yu-Mei Wen
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:58
  35. Immunocytochemistry and RT-PCR have been widely used for the detection of circulating tumor cells in patients with breast cancer but their specificity is limited. Our purpose is to utilize a convenient and spe...

    Authors: Lili Wang, Yanyan Wang, Yajing Liu, Min Cheng, Xu Wu and Haiming Wei
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:57
  36. Tumorigenesis is thought to be the consequence of gene mutation and disordered gene expression. However, the detailed molecular mechanism underlying the development and progress of colon cancer have not been e...

    Authors: Bo Zhang, Xukai Wang and Yan Wang
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:56
  37. To investigate influencing factors of the metastatic lymph nodes ratio (MLR) and whether it is related to survival in patients with gastric adenocarcinoma.

    Authors: Ji-wei Yu, Ju-gang Wu, Lin-hai Zheng, Biao Zhang, Xiao-chun Ni, Xiao-qiang Li and Bo-jian Jiang
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:55
  38. Correction to Kleiner HE, Krishnan P, Tubbs J, Smith M, Meschonat C, Shi R, Lowery-Nordberg M, Adegboyega P, Unger M, Cardelli J et al: Tissue microarray analysis of eIF4E and its downstream effector proteins in ...

    Authors: Heather E Kleiner, Prasad Krishnan, Jesse Tubbs, Mark Smith, Carol Meschonat, Runhua Shi, Mary Lowery-Nordberg, Patrick Adegboyega, Marcia Unger, James Cardelli, Quyen Chu, J Michael Mathis, John Clifford, Arrigo De Benedetti and Benjamin DL Li
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:54

    The original article was published in Journal of Experimental & Clinical Cancer Research 2009 28:5

  39. Patients received electrochemotherapy often associated with unpleasant sensations mainly result from low-frequency electric pulse induced muscle contractions. Increasing the repetition frequency of electric pu...

    Authors: Xiao-Jun Yang, Jun Li, Cai-Xin Sun, Fei-Yun Zheng and Li-Na Hu
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:53
  40. RhoA and RhoC are deregulated by over expression in many human tumors, including colorectal cancer. Some reports show that they play a pivotal role in the carcinogenesis, tumor development and infiltration met...

    Authors: Xiang-ping Liu, Hai-bo Wang, Kun Yang, Ai-hua Sui, Qiang Shi and Shen Qu
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:52
  41. Because in vitro studies suggest that low levels of electromagnetic fields may modify cancer cell growth, we hypothesized that systemic delivery of a combination of tumor-specific frequencies may have a therapeut...

    Authors: Alexandre Barbault, Frederico P Costa, Brad Bottger, Reginald F Munden, Fin Bomholt, Niels Kuster and Boris Pasche
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:51
  42. Considering that HTB140 melanoma cells have shown a poor response to either protons or alkylating agents, the effects of a combined use of these agents have been analysed.

    Authors: Aleksandra M Ristić-Fira, Lela B Korićanac, Jelena J Žakula, Lucia M Valastro, Gioacchin Iannolo, Giuseppe Privitera, Giacomo Cuttone and Ivan M Petrović
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:50
  43. Endometriosis is a gynecological disease defined by the histological presence of endometrial glands and stroma outside the uterine cavity. Women with endometriosis have an increased risk of different types of ...

    Authors: Pietro G Signorile, Feliciano Baldi, Rossana Bussani, Mariarosaria D'Armiento, Maria De Falco and Alfonso Baldi
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:49
  44. Uveal melanoma (UM) cell lines, when exposed to blue light in vitro, show a significant increase in proliferation. In order to determine if similar effects could be seen in vivo, we investigated the effect of ...

    Authors: Sebastian Di Cesare, Shawn Maloney, Bruno F Fernandes, Claudia Martins, Jean-Claude Marshall, Emilia Antecka, Alexandre N Odashiro, William W Dawson and Miguel N Burnier Jr
    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:48

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