Parkin DM, Bray F, Ferlay J, Pisani P: Global cancer statistics, 2002. Ca-a Cancer Journal for Clinicians. 2005, 55: 74-108. 10.3322/canjclin.55.2.74.
Article
Google Scholar
Yang JD, Nakamura I, Roberts LR: The tumor microenvironment in hepatocellular carcinoma: current status and therapeutic targets. Semin Cancer Biol. 2011, 21: 35-43. 10.1016/j.semcancer.2010.10.007.
Article
CAS
Google Scholar
Amann T, Bataille F, Spruss T, Muhlbauer M, Gabele E, Scholmerich J, Kiefer P, Bosserhoff AK, Hellerbrand C: Activated hepatic stellate cells promote tumorigenicity of hepatocellular carcinoma. Cancer Sci. 2009, 100: 646-653. 10.1111/j.1349-7006.2009.01087.x.
Article
CAS
Google Scholar
Santamato A, Fransvea E, Dituri F, Caligiuri A, Quaranta M, Niimi T, Pinzani M, Antonaci S, Giannelli G: Hepatic stellate cells stimulate HCC cell migration via laminin-5 production. Clin Sci. 2011, 121: 159-168. 10.1042/CS20110002.
Article
CAS
Google Scholar
Zhao W, Zhang L, Yin Z, Su W, Ren G, Zhou C, You J, Fan J, Wang X: Activated hepatic stellate cells promote hepatocellular carcinoma development in immunocompetent mice. Int J Cancer. 2011, 129: 2651-2661. 10.1002/ijc.25920.
Article
CAS
Google Scholar
Mantovani A, Sica A, Allavena P, Garlanda C, Locati M: Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation. Hum Immunol. 2009, 70: 325-330. 10.1016/j.humimm.2009.02.008.
Article
CAS
Google Scholar
Lewis CE, Pollard JW: Distinct role of macrophages in different tumor microenvironments. Cancer Res. 2006, 66: 605-612. 10.1158/0008-5472.CAN-05-4005.
Article
CAS
Google Scholar
Ingthorsson S, Sigurdsson V, Fridriksdottir A, Jonasson JG, Kjartansson J, Magnusson MK, Gudjonsson T: Endothelial cells stimulate growth of normal and cancerous breast epithelial cells in 3D culture. BMC research notes. 2010, 3: 184-10.1186/1756-0500-3-184.
Article
Google Scholar
Neiva KG, Zhang Z, Miyazawa M, Warner KA, Karl E, Nor JE: Cross talk initiated by endothelial cells enhances migration and inhibits anoikis of squamous cell carcinoma cells through STAT3/Akt/ERK signaling. Neoplasia. 2009, 11: 583-593.
Article
CAS
Google Scholar
Ding T, Xu J, Zhang Y, Guo RP, Wu WC, Zhang SD, Qian CN, Zheng L: Endothelium-coated tumor clusters are associated with poor prognosis and micrometastasis of hepatocellular carcinoma after resection. Cancer. 2011, 117: 4878-4889. 10.1002/cncr.26137.
Article
Google Scholar
Li Y, Tian B, Yang J, Zhao L, Wu X, Ye SL, Liu YK, Tang ZY: Stepwise metastatic human hepatocellular carcinoma cell model system with multiple metastatic potentials established through consecutive in vivo selection and studies on metastatic characteristics. J Cancer Res Clin Oncol. 2004, 130: 460-468.
Article
CAS
Google Scholar
Cui JF, Liu YK, Zhang LJ, Shen HL, Song HY, Dai Z, Yu YL, Zhang Y, Sun RX, Chen J, et al: Identification of metastasis candidate proteins among HCC cell lines by comparative proteome and biological function analysis of S100A4 in metastasis in vitro. Proteomics. 2006, 6: 5953-5961. 10.1002/pmic.200500460.
Article
CAS
Google Scholar
Wang Y, Wang W, Wang L, Wang X, Xia J: Regulatory mechanisms of interleukin-8 production induced by tumour necrosis factor-alpha in human hepatocellular carcinoma cells. J Cell Mol Med. 2012, 16: 496-506. 10.1111/j.1582-4934.2011.01337.x.
Article
Google Scholar
Tang J, Cui J, Chen R, Guo K, Kang X, Li Y, Gao D, Sun L, Xu C, Chen J, et al: A three-dimensional cell biology model of human hepatocellular carcinoma in vitro. Tumour Biol. 2011, 32: 469-479. 10.1007/s13277-010-0140-7.
Article
Google Scholar
Kong J, Kong L, Kong J, Ke S, Gao J, Ding X, Zheng L, Sun H, Sun W: After insufficient radiofrequency ablation, tumor-associated endothelial cells exhibit enhanced angiogenesis and promote invasiveness of residual hepatocellular carcinoma. J Transl Med. 2012, 10: 230-10.1186/1479-5876-10-230.
Article
CAS
Google Scholar
Yang ZF, Poon RT: Vascular changes in hepatocellular carcinoma. Anatomical record (Hoboken, NJ: 2007). 2008, 291: 721-734. 10.1002/ar.20668.
Article
CAS
Google Scholar
Xiong YQ, Sun HC, Zhang W, Zhu XD, Zhuang PY, Zhang JB, Wang L, Wu WZ, Qin LX, Tang ZY: Human hepatocellular carcinoma tumor-derived endothelial cells manifest increased angiogenesis capability and drug resistance compared with normal endothelial cells. Clin Cancer Res. 2009, 15: 4838-4846. 10.1158/1078-0432.CCR-08-2780.
Article
CAS
Google Scholar
Zhang T, Sun HC, Xu Y, Zhang KZ, Wang L, Qin LX, Wu WZ, Liu YK, Ye SL, Tang ZY: Overexpression of platelet-derived growth factor receptor alpha in endothelial cells of hepatocellular carcinoma associated with high metastatic potential. Clin Cancer Res. 2005, 11: 8557-8563. 10.1158/1078-0432.CCR-05-0944.
Article
CAS
Google Scholar
Serrati S, Margheri F, Fibbi G, Di Cara G, Minafra L, Pucci-Minafra I, Liotta F, Annunziato F, Pucci M, Del Rosso M: Endothelial cells and normal breast epithelial cells enhance invasion of breast carcinoma cells by CXCR-4-dependent up-regulation of urokinase-type plasminogen activator receptor (uPAR, CD87) expression. J Pathol. 2008, 214: 545-554. 10.1002/path.2309.
Article
CAS
Google Scholar
Kaneko T, Zhang Z, Mantellini MG, Karl E, Zeitlin B, Verhaegen M, Soengas MS, Lingen M, Strieter RM, Nunez G, Nor JE: Bcl-2 orchestrates a cross-talk between endothelial and tumor cells that promotes tumor growth. Cancer Res. 2007, 67: 9685-9693. 10.1158/0008-5472.CAN-07-1497.
Article
CAS
Google Scholar
Franses JW, Baker AB, Chitalia VC, Edelman ER: Stromal endothelial cells directly influence cancer progression. Sci Transl Med. 2011, 3: 66ra65-
Article
Google Scholar
Shi CL, Yu CH, Zhang Y, Zhao D, Chang XH, Wang WH: Monocyte chemoattractant protein-1 modulates invasion and apoptosis of PC-3M prostate cancer cells via regulating expression of VEGF, MMP9 and caspase-3. APJCP. 2011, 12: 555-559.
Google Scholar
Zhang J, Lu Y, Pienta KJ: Multiple roles of chemokine (C-C motif) ligand 2 in promoting prostate cancer growth. J Natl Cancer Inst. 2010, 102: 522-528. 10.1093/jnci/djq044.
Article
CAS
Google Scholar
Yoshimura T, Howard OM, Ito T, Kuwabara M, Matsukawa A, Chen K, Liu Y, Liu M, Oppenheim JJ, Wang JM: Monocyte chemoattractant protein-1/CCL2 produced by stromal cells promotes lung metastasis of 4T1 murine breast cancer cells. PLoS One. 2013, 8: e58791-10.1371/journal.pone.0058791.
Article
CAS
Google Scholar
Dagouassat M, Suffee N, Hlawaty H, Haddad O, Charni F, Laguillier C, Vassy R, Martin L, Schischmanoff PO, Gattegno L, et al: Monocyte chemoattractant protein-1 (MCP-1)/CCL2 secreted by hepatic myofibroblasts promotes migration and invasion of human hepatoma cells. Int J Cancer. 2010, 126: 1095-1108.
CAS
Google Scholar
Lu Y, Wang J, Xu Y, Koch AE, Cai Z, Chen X, Galson DL, Taichman RS, Zhang J: CXCL16 functions as a novel chemotactic factor for prostate cancer cells in vitro. Mol Cancer Res. 2008, 6: 546-554. 10.1158/1541-7786.MCR-07-0277.
Article
CAS
Google Scholar
Hojo S, Koizumi K, Tsuneyama K, Arita Y, Cui Z, Shinohara K, Minami T, Hashimoto I, Nakayama T, Sakurai H, et al: High-level expression of chemokine CXCL16 by tumor cells correlates with a good prognosis and increased tumor-infiltrating lymphocytes in colorectal cancer. Cancer Res. 2007, 67: 4725-4731. 10.1158/0008-5472.CAN-06-3424.
Article
CAS
Google Scholar
Wente MN, Gaida MM, Mayer C, Michalski CW, Haag N, Giese T, Felix K, Bergmann F, Giese NA, Friess H: Expression and potential function of the CXC chemokine CXCL16 in pancreatic ductal adenocarcinoma. Int J Oncol. 2008, 33: 297-308.
CAS
Google Scholar
Ou DL, Chen CL, Lin SB, Hsu CH, Lin LI: Chemokine receptor expression profiles in nasopharyngeal carcinoma and their association with metastasis and radiotherapy. J Pathol. 2006, 210: 363-373. 10.1002/path.2053.
Article
CAS
Google Scholar
Held-Feindt J, Rehmke B, Mentlein R, Hattermann K, Knerlich F, Hugo HH, Ludwig A, Mehdorn HM: Overexpression of CXCL16 and its receptor CXCR6/Bonzo promotes growth of human schwannomas. Glia. 2008, 56: 764-774. 10.1002/glia.20651.
Article
Google Scholar
Gao Q, Zhao YJ, Wang XY, Qiu SJ, Shi YH, Sun J, Yi Y, Shi JY, Shi GM, Ding ZB, et al: CXCR6 upregulation contributes to a proinflammatory tumor microenvironment that drives metastasis and poor patient outcomes in hepatocellular carcinoma. Cancer Res. 2012, 72: 3546-3556. 10.1158/0008-5472.CAN-11-4032.
Article
CAS
Google Scholar
Waugh DJ, Wilson C: The interleukin-8 pathway in cancer. Clin Cancer Res. 2008, 14: 6735-6741. 10.1158/1078-0432.CCR-07-4843.
Article
CAS
Google Scholar
Sakamoto K, Masuda T, Mita S, Ishiko T, Nakashima Y, Arakawa H, Egami H, Harada S, Matsushima K, Ogawa M: Interleukin-8 is constitutively and commonly produced by various human carcinoma cell-lines. Int J Clin Lab Res. 1992, 22: 216-219. 10.1007/BF02591427.
Article
CAS
Google Scholar
Inoue K, Slaton JW, Kim SJ, Perrotte P, Eve BY, Bar-Eli M, Radinsky R, Dinney CP: Interleukin 8 expression regulates tumorigenicity and metastasis in human bladder cancer. Cancer Res. 2000, 60: 2290-2299.
CAS
Google Scholar
Boldrini L, Gisfredi S, Ursino S, Lucchi M, Mussi A, Basolo F, Pingitore R, Fontanini G: Interleukin-8 in non-small cell lung carcinoma: relation with angiogenic pattern and p53 alterations. Lung Cancer. 2005, 50: 309-317. 10.1016/j.lungcan.2005.07.002.
Article
Google Scholar
Benoy IH, Salgado R, Van Dam P, Geboers K, Van Marck E, Scharpe S, Vermeulen PB, Dirix LY: Increased serum interleukin-8 in patients with early and metastatic breast cancer correlates with early dissemination and survival. Clin Cancer Res. 2004, 10: 7157-7162. 10.1158/1078-0432.CCR-04-0812.
Article
CAS
Google Scholar
Ren Y, Poon RT, Tsui HT, Chen WH, Li Z, Lau C, Yu WC, Fan ST: Interleukin-8 serum levels in patients with hepatocellular carcinoma: correlations with clinicopathological features and prognosis. Clin Cancer Res. 2003, 9: 5996-6001.
CAS
Google Scholar
Liu Z, Yang L, Xu J, Zhang X, Wang B: Enhanced expression and clinical significance of chemokine receptor CXCR2 in hepatocellular carcinoma. J Surg Res. 2011, 166: 241-246. 10.1016/j.jss.2009.07.014.
Article
CAS
Google Scholar
Kubo F, Ueno S, Hiwatashi K, Sakoda M, Kawaida K, Nuruki K, Aikou T: Interleukin 8 in human hepatocellular carcinoma correlates with cancer cell invasion of vessels but not with tumor angiogenesis. Ann Surg Oncol. 2005, 12: 800-807. 10.1245/ASO.2005.07.015.
Article
Google Scholar
Fabregat I, Roncero C, Fernandez M: Survival and apoptosis: a dysregulated balance in liver cancer. Liver Int. 2007, 27: 155-162. 10.1111/j.1478-3231.2006.01409.x.
Article
CAS
Google Scholar
Honma N, Genda T, Matsuda Y, Yamagiwa S, Takamura M, Ichida T, Aoyagi Y: MEK/ERK signaling is a critical mediator for integrin-induced cell scattering in highly metastatic hepatocellular carcinoma cells. Lab Invest. 2006, 86: 687-696. 10.1038/labinvest.3700427.
Article
CAS
Google Scholar
Saxena NK, Sharma D, Ding X, Lin S, Marra F, Merlin D, Anania FA: Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells. Cancer Res. 2007, 67: 2497-2507. 10.1158/0008-5472.CAN-06-3075.
Article
CAS
Google Scholar
Schmitz KJ, Wohlschlaeger J, Lang H, Sotiropoulos GC, Malago M, Steveling K, Reis H, Cicinnati VR, Schmid KW, Baba HA: Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infection. J Hepatol. 2008, 48: 83-90. 10.1016/j.jhep.2007.08.018.
Article
CAS
Google Scholar
Lou L, Ye W, Chen Y, Wu S, Jin L, He J, Tao X, Zhu J, Chen X, Deng A, Wang J: Ardipusilloside inhibits survival, invasion and metastasis of human hepatocellular carcinoma cells. Phytomedicine. 2012, 19: 603-608. 10.1016/j.phymed.2012.01.003.
Article
CAS
Google Scholar
Chen JS, Wang Q, Fu XH, Huang XH, Chen XL, Cao LQ, Chen LZ, Tan HX, Li W, Bi J, Zhang LJ: Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: association with MMP-9. Hepatol Res. 2009, 39: 177-186. 10.1111/j.1872-034X.2008.00449.x.
Article
CAS
Google Scholar
Tang CH, Tsai CC: CCL2 increases MMP-9 expression and cell motility in human chondrosarcoma cells via the Ras/Raf/MEK/ERK/NF-kappaB signaling pathway. Biochem Pharmacol. 2012, 83: 335-344. 10.1016/j.bcp.2011.11.013.
Article
CAS
Google Scholar
Wang J, Lu Y, Wang J, Koch AE, Zhang J, Taichman RS: CXCR6 induces prostate cancer progression by the AKT/mammalian target of rapamycin signaling pathway. Cancer Res. 2008, 68: 10367-10376. 10.1158/0008-5472.CAN-08-2780.
Article
CAS
Google Scholar
Hsiang CY, Wu SL, Chen JC, Lo HY, Li CC, Chiang SY, Wu HC, Ho TY: Acetaldehyde induces matrix metalloproteinase-9 gene expression via nuclear factor-kappaB and activator protein 1 signaling pathways in human hepatocellular carcinoma cells: association with the invasive potential. Toxicol Lett. 2007, 171: 78-86. 10.1016/j.toxlet.2007.04.009.
Article
CAS
Google Scholar
Li J, Lau GK, Chen L, Dong SS, Lan HY, Huang XR, Li Y, Luk JM, Yuan YF, Guan XY: Interleukin 17A promotes hepatocellular carcinoma metastasis via NF-kB induced matrix metalloproteinases 2 and 9 expression. PloS one. 2011, 6: e21816-10.1371/journal.pone.0021816.
Article
CAS
Google Scholar