Owned by the Association for International Promotion & Study in Tumors (APSIT)
Articles
Page 69 of 73
-
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:137
-
In vivo99mTc-HYNIC-annexin V imaging of early tumor apoptosis in mice after single dose irradiation
Apoptosis is a major mode of hematological tumor death after radiation. Early detection of apoptosis may be beneficial for cancer adaptive treatment. 99mTc-HYNIC-annexinV has been reported as a promising agent fo...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:136 -
Urinary estrogen metabolites and prostate cancer: a case-control study and meta-analysis
To investigate prostate cancer (Pca) risk in relation to estrogen metabolism, expressed as urinary 2-hydroxyestrone (2-OHE1), 16α-hydroxyestrone (16α-OHE1) and 2-OHE1 to 16α-OHE1 ratio.
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:135 -
Chromophobe renal cell cancer - review of the literature and potential methods of treating metastatic disease
Chromophobe renal cell carcinoma (ChRCC) is a subtype of renal cell carcinoma (RCC). ChRCC is diagnosed mainly in 6th decade of life. An incidence of ChRCC is similar in both men and woman. Eighty six percent ...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:134 -
Generation of fusion protein EGFRvIII-HBcAg and its anti-tumor effect in vivo
The epidermal growth factor receptor variant III (EGFRvIII) is the most common variation of EGFR. Because it shows a high frequency in several different types of tumor and has not been detected in normal tissu...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:133 -
MMP7 expression regulated by endocrine therapy in ERβ-positive colon cancer cells
Many studies have shown that colon cancer is an estrogen-dependent carcinoma. This study explored the efficacy of endocrine therapy in colon cancer cells with high metastatic potential (HT29). We investigated ...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:132 -
Clinical research of Olanzapine for prevention of chemotherapy-induced nausea and vomiting
This study was designed to mainly evaluate the activity and safety of olanzapine compared with 5-hydroxytryptamine3(5-HT3) receptor antagonists for prevention of chemotherapy-induced nausea and vomiting(CINV) in ...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:131 -
The expression of PLK-1 in cervical carcinoma: a possible target for enhancing chemosensitivity
Polo-like kinase-1 (PLK-1) is reported to be upregulated in a variety of human tumors and is implicated in cell proliferation and survival. However, its importance in cervical carcinoma has not yet been fully ...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:130 -
Transcription factor Sp1 induces ADAM17 and contributes to tumor cell invasiveness under hypoxia
Expression of the Sp1 transcription factor is induced by hypoxia, and the ADAM17 promoter contains predicted Sp1 binding sites. ADAM17 contributes to hypoxic-induce invasiveness of glioma. In this study, we in...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:129 -
Sexual dysfunction following surgery for rectal cancer - a clinical and neurophysiological study
Sexual dysfunction following surgery for rectal cancer may be frequent and often severe. The aim of the present study is to evaluate the occurrence of this complication from both a clinical point of view and b...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:128 -
Characterization of human breast cancer epithelial cells (HBCEC) derived from long term cultured biopsies
For a more individualized therapeutic approach we explored a protease-free method to culture primary cells from breast cancer biopsies.
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:127 -
Mining novel biomarkers for prognosis of gastric cancer with serum proteomics
Although gastric caner (GC) remains the second cause of cancer-related death, useful biomarkers for prognosis are still unavailable. We present here the attempt of mining novel biomarkers for GC prognosis by u...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:126 -
Loss of imprinting of insulin-like growth factor 2 is associated with increased risk of lymph node metastasis and gastric corpus cancer
The aim of this study was to determine the clinicopathological features of gastric cancers with loss of imprinting (LOI) of LIT1. Insulin-like growth factor 2 (IGF2) and H19 in Chinese patients.
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:125 -
Effect of Genistein on vasculogenic mimicry formation by human uveal melanoma cells
Vasculogenic mimicry (VM) was increasingly recognized as a form of aggressive melanoma acquiring blood supply. Genistein had attracted much attention as a potential anticancer agent. Therefore, we examined the...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:124 -
The drug-resistance to gefitinib in PTEN low expression cancer cells is reversed by irradiation in vitro
Despite of the recent success of EGFR inhibitory agents, the primary drug-resistant becomes a major challenge for EGFR inhibitor therapies. PTEN gene is an important positive regulatory factor for response to ...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:123 -
Proteomic analysis of differentially expressed proteins in hepatitis B virus-related hepatocellular carcinoma tissues
Hepatocellular carcinoma (HCC), a major cause of cancer death in China, is preceded by chronic hepatitis and liver cirrhosis (LC). Although hepatitis B virus (HBV) has been regarded as a clear etiology of huma...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:122 -
Breast cancer humoral immune response: involvement of Lewis y through the detection of circulating immune complexes and association with Mucin 1 (MUC1)
In cancer patients, MUC1 glycoprotein may carry Lewis y which could be involved in immune response. Purposes: 1- to evaluate the presence of Lewis y and MUC1 in circulating immune complexes (Lewis y/CIC and MU...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:121 -
Serum human chorionic gonadotropin is associated with angiogenesis in germ cell testicular tumors
Germ cell testicular tumors have survival rate that diminishes with high tumor marker levels, such as human chorionic gonadotropin (hCG). hCG may regulate vascular neoformation through vascular endothelial gro...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:120 -
Oxaliplatin-dacarbazine combination chemotherapy for the treatment of advanced soft tissue sarcoma of the limbs
This study was designed to explore the feasibility, safety, and outcomes of pre-operative oxaliplatin-dacarbazine combination therapy for the treatment of advanced soft tissue sarcoma (STS) of the limb.
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:119 -
Does vimentin help to delineate the so-called 'basal type breast cancer'?
Vimentin is one of the cytoplasmic intermediate filament proteins which are the major component of the cytoskeleton. In our study we checked the usefulness of vimentin expression in identifying cases of breast...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:118 -
Modeling of α/β for late rectal toxicity from a randomized phase II study: conventional versus hypofractionated scheme for localized prostate cancer
Recently, the use of hypo-fractionated treatment schemes for the prostate cancer has been encouraged due to the fact that α/β ratio for prostate cancer should be low. However a major concern on the use of hypo...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:117 -
Impact of relative dose intensity (RDI) in CHOP combined with rituximab (R-CHOP) on survival in diffuse large B-cell lymphoma
Recently, maintaining higher relative dose intensity (RDI) of chemotherapeutic drugs has become a widespread practice in an attempt to achieve better outcomes in the treatment of aggressive lymphoma. The addit...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:116 -
Polymorphisms of TP53 codon 72 with breast carcinoma risk: evidence from 12226 cases and 10782 controls
Previously, TP53 codon 72 polymorphisms have been implicated as risk factors for various cancers. A number of studies have conducted on the association of TP53 codon 72 polymorphisms with susceptibility to bre...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:115 -
Adjuvant electrochemotherapy in veterinary patients: a model for the planning of future therapies in humans
The treatment of soft tissue tumors needs the coordinated adoption of surgery with radiation therapy and eventually, chemotherapy. The radiation therapy (delivered with a linear accelerator) can be preoperativ...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:114 -
Association of cetuximab with adverse pulmonary events in cancer patients: a comprehensive review
Compounds derived from biologic sources, or biologicals, are increasingly utilized as therapeutic agents in malignancy. Development of anti-cancer targeted therapies from biologics is increasingly being utiliz...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:113 -
Traditional Chinese medicines in the treatment of hepatocellular cancers: a systematic review and meta-analysis
Liver cancer is a common malignancy with a high mortality rate. Given the poor prognosis associated with this cancer, many patients seek additional therapies that may improve quality of life or survival. Sever...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:112 -
Subcellular localization of APMCF1 and its biological significance of expression pattern in normal and malignant human tissues
APMCF1 is a novel human gene first cloned from apoptotic MCF-7 cells. Our previous study found ectogenic APMCF1 could induce G1 arrest in hepatocarcinoma cell line HHCC. In order to search its broad expression...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:111 -
Arsenic trioxide exerts synergistic effects with cisplatin on non-small cell lung cancer cells via apoptosis induction
Despite multidisciplinary treatment, lung cancer remains a highly lethal disease due to poor response to chemotherapy. The identification of therapeutic agents with synergistic effects with traditional drugs i...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:110 -
Multicenter safety study of mFOLFOX6 for unresectable advanced/recurrent colorectal cancer in elderly patients
Combination chemotherapy with oxaliplatin plus 5-fluorouracil/leucovorin (FOLFOX) has become a standard regimen for colorectal cancer. An increase of adverse events with combination chemotherapy is predicted i...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:109 -
CDX2 hox gene product in a rat model of esophageal cancer
Barrett's mucosa is the precursor of esophageal adenocarcinoma. The molecular mechanisms behind Barrett's carcinogenesis are largely unknown. Experimental models of longstanding esophageal reflux of duodenal-g...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:108 -
Characteristic gene expression profiles in the progression from liver cirrhosis to carcinoma induced by diethylnitrosamine in a rat model
Liver cancr is a heterogeneous disease in terms of etiology, biologic and clinical behavior. Very little is known about how many genes concur at the molecular level of tumor development, progression and aggres...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:107 -
Mutation analysis of Rad18 in human cancer cell lines and non small cell lung cancer tissues
Genetic instability is known as a cause of oncogenesis. Though Rad18 is reported to function in a post replication mismatch repair system, the relation between the status of Rad18 and human tumorigenesis has n...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:106 -
Risedronate inhibits human osteosarcoma cell invasion
Osteosarcoma is a highly malignant bone tumor and is the most commonly encountered malignant bone tumor in children and adolescents. Furthermore, significant numbers of patients eventually develop pulmonary me...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:105 -
Statistically significant association of the single nucleotide polymorphism (SNP) rs13181 (ERCC2) with predisposition to Squamous Cell Carcinomas of the Head and Neck (SCCHN) and Breast cancer in the north Indian population
Non-synonymous single nucleotide polymorphisms (SNPs) within vital DNA repair genes may cause reduction of activity leaving the genome unrepaired resulting in genomic instability and cancer.
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:104 -
Lung cancer gene expression database analysis incorporating prior knowledge with support vector machine-based classification method
A reliable and precise classification is essential for successful diagnosis and treatment of cancer. Gene expression microarrays have provided the high-throughput platform to discover genomic biomarkers for ca...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:103 -
Substance P and beta-endorphin mediate electro-acupuncture induced analgesia in mouse cancer pain model
Opioid analgesics are generally used to combat the pain associated with cancerous conditions. These agents not only inhibit respiratory function and cause constipation, but also induce other significant side e...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:102 -
Retraction Note: siRNA directed against c-Myc inhibits proliferation and downregulates human telomerase reverse transcriptase in human colon cancer Colo 320 cells
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:101 -
The calcimimetic R-568 induces apoptotic cell death in prostate cancer cells
Increased serum level of parathyroid hormone (PTH) was found in metastatic prostate cancers. Calcimimetic R-568 was reported to reduce PTH expression, to suppress cell proliferation and to induce apoptosis in ...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:100 -
Influence of the dual ABCB1 and ABCG2 inhibitor tariquidar on the disposition of oral imatinib in mice
Imatinib, a tyrosine kinase inhibitor currently approved for treatment of several malignancies, has been shown to be a substrate for multiple efflux-transporter proteins, including ABCB1 (P-glycoprotein) and A...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:99 -
The role of VEGF-C/D and Flt-4 in the lymphatic metastasis of early-stage invasive cervical carcinoma
To investigate the role of vascular endothelial growth factors (VEGF)-C/D and their receptor Flt-4 in the lymphatic metastasis of early-stage invasive cervical carcinoma.
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:98 -
The effect of HER2 expression on cisplatin-based chemotherapy in advanced non-small cell lung cancer patients
The prognostic value of HER2 expression in patients with advanced non-small cell lung cancer remains controversial. The relationship between HER2 expression, and platinum resistance and patient survival, was i...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:97 -
Resveratrol exhibits a strong cytotoxic activity in cultured cells and has an antiviral action against polyomavirus: potential clinical use
Resveratrol is a non flavonoid polyphenol compound present in many plants and fruits and, at especially high concentrations, in the grape berries of Vitis vinifera. This compound has a strong bioactivity and its ...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:96 -
Comparison of conventional and CT-based planning for intracavitary brachytherapy for cervical cancer: target volume coverage and organs at risk doses
To compare intracavitary brachytherapy (ICBT) planning methods for cervical cancer, based on either orthogonal radiographs (conventional plan) or CT sections (CT plan); the comparison focused on target volume ...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:95 -
Polymorphisms of TGFB1 and VEGF genes and survival of patients with gastric cancer
Some TGFB1 and VEGF polymorphisms are believed to be functional. Given that these genes are involved in tumor growth and progression including angiogenesis, dissemination, and invasiveness, we hypothesized that t...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:94 -
Overexpression of peroxiredoxin I and thioredoxin1 in human breast carcinoma
Peroxiredoxins (Prxs) are a novel group of peroxidases containing high antioxidant efficiency. The mammalian Prx family has six distinct members (Prx I-VI) in various subcellular locations, including peroxisom...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:93 -
Phenotype-dependent apoptosis signalling in mesothelioma cells after selenite exposure
Selenite is a promising anticancer agent which has been shown to induce apoptosis in malignant mesothelioma cells in a phenotype-dependent manner, where cells of the chemoresistant sarcomatoid phenotype are mo...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:92 -
The association of XRCC1gene single nucleotide polymorphisms with response to neoadjuvant chemotherapy in locally advanced cervical carcinoma
Platinum-based neoadjuvant chemotherapy (NAC) is new therapeutic strategy for locally advanced cervical carcinoma, but the variables used to predict NAC response are still infrequently reported. The aim of our...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:91 -
CHOP5'UTR-c.279T>C and +nt30C>T variants are not associated with overweight condition or with tumors/cancer in Italians – a case-control study
Type 2 diabetes (T2D) is associated with obesity and has been shown recently to be associated with tumors/cancer. HNF1-beta and JAZF1 genes are associated with T2D and prostate cancer. We have previously shown th...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:90 -
IGF-I and IGFBP-3 and the risk of lung cancer: A meta-analysis based on nested case-control studies
Lung cancer is the leading cause of death from cancer worldwide. Conventional studies mainly think that insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 (IGFBP-3) may promote and inhibit tumor gr...
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:89 -
Intraoperative ultrasound-guided iodine-125 seed implantation for unresectable pancreatic carcinoma
To assess the feasibility and efficacy of using 125I seed implantation under intraoperative ultrasound guidance for unresectable pancreatic carcinoma.
Citation: Journal of Experimental & Clinical Cancer Research 2009 28:88
-
-
-
Official journal of the Regina Elena National Cancer Institute, Scientific Director Gennaro Ciliberto, Rome, Italy
-
- Editorial Board
- Manuscript editing services
- Instructions for Editors
- Sign up for article alerts and news from this journal
Annual Journal Metrics
-
2022 Citation Impact
11.3 - 2-year Impact Factor
11.5 - 5-year Impact Factor
1.870 - SNIP (Source Normalized Impact per Paper)
2.413 - SJR (SCImago Journal Rank)2022 Speed
4 days submission to first editorial decision for all manuscripts (Median)
97 days submission to accept (Median)2022 Usage
2,694,347 downloads
4,666 Altmetric mentions