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  1. Esophageal squamous cell carcinoma (ESCC) is one of the most prevalent gastrointestinal malignancies with high mortality. Circular RNAs (CircRNAs) have become a research hotspot in recent years for their vital...

    Authors: Xiaoqi Chen, Jing Jiang, Yunxia Zhao, Xinting Wang, Chuanlei Zhang, Lv Zhuan, Danyang Zhang and Yuling Zheng

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:133

    Content type: Research

    Published on:

  2. Crosstalk between cancer cells and tumor-associated macrophages (TAMs) mediates tumor progression in colorectal cancer (CRC). Cytoplasmic polyadenylation element binding protein 3 (CPEB3) has been shown to exh...

    Authors: Qian Zhong, Yuxin Fang, Qiuhua Lai, Shanci Wang, Chengcheng He, Aimin Li, Side Liu and Qun Yan

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:132

    Content type: Research

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  3. Esophageal cancer (EC) represents one of the most aggressive digestive neoplasms globally, with marked geographical variations in morbidity and mortality. Chemoprevention is a promising approach for cancer the...

    Authors: Shuyao Zhang, Fuchun Zheng, Liqun Zhang, Zuojun Huang, Xiaoshan Huang, Zhen Pan, Shuang Chen, Chenchen Xu, Yi Jiang, Shuyi Gu, Chengkuan Zhao, Qiuzhen Zhang and Ganggang Shi

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:131

    Content type: Research

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  4. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Yujun Tang, Yishi Lu, Yuan Cheng, Lei Luo, Lei Cai, Bangjian Peng, Wenbin Huang, Hangyu Liao, Liang Zhao and Mingxin Pan

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:130

    Content type: Correction

    Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2019 38:473

  5. Radiotherapy is the cornerstone of treatment of high-grade gliomas (HGGs). It eradicates tumor cells by inducing oxidative stress and subsequent DNA damage. Unfortunately, almost all HGGs recur locally within ...

    Authors: Han Shen, Kristina Cook, Harriet E. Gee and Eric Hau

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:129

    Content type: Review

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  6. Hepatocellular carcinoma is the third top cause of cancer-related mortalities worldwide. The prognosis of HCC patients remains poor due to rapid progression and high incidence of tumor recurrence. Nicastrin (N...

    Authors: Hui Li, Tian Lan, Lin Xu, Hailing Liu, Jinju Wang, Jiaxin Li, Xiangzheng Chen, Jiwei Huang, Xuefeng Li, Kefei Yuan, Yong Zeng and Hong Wu

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:128

    Content type: Research

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  7. Recent studies have shown that the classic hypoglycemic drug metformin inhibits tumor growth; however, the underlying mechanism remains unclear. We previously showed that metformin disrupts the sponge effect o...

    Authors: Chenglai Xia, Chang Liu, Zhihong He, Yantao Cai and Jinman Chen

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:127

    Content type: Research

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  8. Liver cancer has become the sixth most diagnosed cancer and the fourth leading cause of cancer death worldwide. Hepatocellular carcinoma (HCC) is responsible for up to 75–85% of primary liver cancers, and sora...

    Authors: Jiao Feng, Jingjing Li, Liwei Wu, Qiang Yu, Jie Ji, Jianye Wu, Weiqi Dai and Chuanyong Guo

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:126

    Content type: Review

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  9. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Zhiyan Hu, Ting Long, Yidan Ma, Jiaxian Zhu, Lingfang Gao, Yan Zhong, Xia Wang, Xiaoyan Wang and Zuguo Li

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:125

    Content type: Correction

    Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2020 39:76

  10. Malformation of blood vessels represents a hallmark of cancers, but the role and regulation of vascular mural cells (vMCs), including vascular smooth muscle cells (vSMCs) and pericytes, in tumors has not been ...

    Authors: Xinxin Zhang, Xianchun Yan, Jing Cao, Ziyan Yang, Xiuli Cao, Yufei Zhang, Liang Liang, Minhua Zheng, Xiaowei Liu, Jian Zhang and Hua Han

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:124

    Content type: Research

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  11. 3-Hydroxy butyrate dehydrogenase 2 (BDH2) is a short-chain dehydrogenase/reductase family member that plays a key role in the development and pathogenesis of human cancers. However, the role of BDH2 in gastric...

    Authors: Jia-Zhou Liu, Yi-Lin Hu, Ying Feng, Yun Jiang, Yi-Bing Guo, Yi-Fei Liu, Xi Chen, Jun-Ling Yang, Yu-yan Chen, Qin-Sheng Mao and Wan-Jiang Xue

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:123

    Content type: Research

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  12. Tumor progression and tumor response to anticancer therapies may be affected by activation of oncogenic pathways such as the antioxidant one induced by NRF2 (nuclear factor erythroid 2-related factor 2) transc...

    Authors: Alessia Garufi, Silvia Baldari, Riccardo Pettinari, Maria Saveria Gilardini Montani, Valerio D’Orazi, Giuseppa Pistritto, Alessandra Crispini, Eugenia Giorno, Gabriele Toietta, Fabio Marchetti, Mara Cirone and Gabriella D’Orazi

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:122

    Content type: Research

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  13. Angiogenesis plays an important role in the progress of glioma. RNA-binding proteins (RBPs) and circular RNAs (circRNAs), dysregulated in various tumors, have been verified to mediate diverse biological behavi...

    Authors: Xiaobai Liu, Shuyuan Shen, Lu Zhu, Rui Su, Jian Zheng, Xuelei Ruan, Lianqi Shao, Di Wang, Chunqing Yang and Yunhui Liu

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:121

    Content type: Research

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  14. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Marco Russano, Andrea Napolitano, Giulia Ribelli, Michele Iuliani, Sonia Simonetti, Fabrizio Citarella, Francesco Pantano, Emanuela Dell’Aquila, Cecilia Anesi, Nicola Silvestris, Antonella Argentiero, Antonio Giovanni Solimando, Bruno Vincenzi, Giuseppe Tonini and Daniele Santini

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:120

    Content type: Correction

    Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2020 39:95

  15. Gastric cancer (GC) is a common form of malignant cancer in worldwide which has a poor prognosis. Despite recent improvements in the treatment of GC, the prognosis is not yet satisfactory for GC patients. CYT997,...

    Authors: Ya Cao, Jinglong Wang, Hua Tian and Guo-Hui Fu

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:119

    Content type: Research

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  16. Gastric cancer (GC) is the most prevalent gastrointestinal tumor with an unfavorable clinical prognosis. GC patients are largely threatened owing to metastasis and drug resistance. Tumor angiogenesis plays an ...

    Authors: Jun-Jie Chen, Yan-Lin Ren, Chuan-Jun Shu, Yi Zhang, Min-Juan Chen, Jin Xu, Jin Li, Ai-Ping Li, Dong-Yin Chen, Jing-Dong He, Yong-Qian Shu and Jian-Wei Zhou

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:118

    Content type: Research

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  17. The discovery of the role of non-coding RNAs (ncRNAs) in the onset and progression of malignancies is a promising frontier of cancer genetics. It is clear that ncRNAs are candidates for therapeutic interventio...

    Authors: Katia Grillone, Caterina Riillo, Francesca Scionti, Roberta Rocca, Giuseppe Tradigo, Pietro Hiram Guzzi, Stefano Alcaro, Maria Teresa Di Martino, Pierosandro Tagliaferri and Pierfrancesco Tassone

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:117

    Content type: Review

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  18. Aberrant alternative splicing events play critical roles in carcinogenesis and progression of many cancers, while sparse studies regarding to alternative splicing are available for clear cell renal cell carcin...

    Authors: Guoliang Sun, Hui Zhou, Ke Chen, Jin Zeng, Yangjun Zhang, Libin Yan, Weimin Yao, Junhui Hu, Tao Wang, Jinchun Xing, Kefeng Xiao, Lily Wu, Zhangqun Ye and Hua Xu

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:116

    Content type: Research

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  19. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Jing Zhang, Xiao-han Liu, Cong Li, Xiao-xing Wu, Yan-lin Chen, Wen-wen Li, Xian Li, Fan Gong, Qin Tang and Dan Jiang

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:115

    Content type: Correction

    Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2020 39:79

  20. Circular RNAs (circRNAs) play a critical regulatory role in cancer progression. However, the underlying mechanisms of circRNAs in hepatocellular carcinoma (HCC) metastasis remain mostly unknown.

    Authors: Li-na Song, Guang-lei Qiao, Jian Yu, Chun-mei Yang, Ying Chen, Zhou-feng Deng, Li-hua Song, Li-jun Ma and Hong-li Yan

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:114

    Content type: Research

    Published on:

  21. Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive tumors in the world. Aryl hydrocarbon receptor (AHR) has been reported to promote tumor metastasis and epithelial-mesenchymal transition ...

    Authors: Peiyao Zhu, Huayun Yu, Kun Zhou, Yu Bai, Ruiqun Qi and Shuguang Zhang

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:113

    Content type: Research

    Published on:

  22. Colorectal cancer is one of most common tumors in developed countries and, despite improvements in treatment and diagnosis, mortality rate of patients remains high, evidencing the urgent need of novel biomarke...

    Authors: Roberto Dinami, Manuela Porru, Carla Azzurra Amoreo, Isabella Sperduti, Marcella Mottolese, Simonetta Buglioni, Daniele Marinelli, Marcello Maugeri-Saccà, Andrea Sacconi, Giovanni Blandino, Carlo Leonetti, Giuliana Di Rocco, Alessandra Verdina, Francesca Spinella, Francesco Fiorentino, Gennaro Ciliberto…

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:111

    Content type: Research

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  23. Hypoxia-induced alternative splicing is a potent driving force in tumour pathogenesis and progression. In this review, we update currents concepts of hypoxia-induced alternative splicing and how it influences ...

    Authors: Antonietta Rosella Farina, Lucia Cappabianca, Michela Sebastiano, Veronica Zelli, Stefano Guadagni and Andrew Reay Mackay

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:110

    Content type: Review

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  24. If we focus our attention on seven main features of COVID-19 infection (heterogeneity, fragility, lack of effective treatments and vaccines, “miraculous cures”, psychological suffering, deprivation, and globaliza...

    Authors: Nicola Silvestris, Giovanni Apolone, Gerardo Botti, Gennaro Ciliberto, Massimo Costantini, Paolo De Paoli, Silvia Franceschi, Giuseppe Opocher, Angelo Paradiso, Paolo Pronzato, Alessandro Sgambato and Ruggero De Maria

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:109

    Content type: Commentary

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  25. Chemo-resistance of bladder cancer has been considered to be one of the serious issues to be solved. In this study, we revealed pivotal role of miR-424 in the regulation of CDDP sensitivity of bladder cancer c...

    Authors: Meng Yu, Toshinori Ozaki, Dan Sun, Haotian Xing, Baojun Wei, Jun An, Jieping Yang, Ying Gao, Shuangjie Liu, Chuize Kong and Yuyan Zhu

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:108

    Content type: Research

    Published on:

  26. Fermented wheat germ extract has been reported to exert various pharmacological activities, including anti-oxidant, anti-cell growth and cell apoptosis in various cancer cells. Although 2,6-dimethoxy-1,4-benzo...

    Authors: Xueyin Zu, Xiaoli Ma, Xiaomeng Xie, Bingbing Lu, Kyle Laster, Kangdong Liu, Zigang Dong and Dong Joon Kim

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:107

    Content type: Research

    Published on:

  27. Acylphosphatase 2 (ACYP2) is involved in cell differentiation, energy metabolism and hydrolysis of intracellular ion pump. It has been reported as a negative regulator in leukemia and a positive regulator in c...

    Authors: Mengdan Li, Banjun Ruan, Jing Wei, Qi Yang, Mingwei Chen, Meiju Ji and Peng Hou

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:106

    Content type: Research

    Published on:

  28. DCZ3301, a novel aryl-guanidino compound previously reported by our group, exerts cytotoxic effects against multiple myeloma (MM), diffused large B cell lymphoma (DLBCL), and T-cell leukemia/lymphoma. However,...

    Authors: Liangning Hu, Bo Li, Gege Chen, Dongliang Song, Zhijian Xu, Lu Gao, Mengyu Xi, Jinfeng Zhou, Liping Li, Hui Zhang, Qilin Feng, Yingcong Wang, Kang Lu, Yumeng Lu, Wenxuan Bu, Houcai Wang…

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:105

    Content type: Research

    Published on:

  29. Although ongoing development of therapeutic strategies contributes to the improvements in clinical management, clear cell renal cell carcinoma (ccRCC) deaths originate mainly from radiochemoresistant and metas...

    Authors: Jinbo Sun, Qisheng Tang, Yongheng Gao, Wei Zhang, Zhining Zhao, Fan Yang, Xiangnan Hu, Dan Zhang, Yong Wang, Huizhong Zhang, Bin Song, Bo Zhang and He Wang

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:104

    Content type: Research

    Published on:

  30. Understanding the signalling pathways involved in angiogenesis, and developing anti-angiogenic drugs are one of the major focuses on cancer research. Herein, we assessed the effect of CPTH6, a lysine acetyltra...

    Authors: Marta Di Martile, Chiara Gabellini, Marianna Desideri, Marta Matraxia, Valentina Farini, Elisabetta Valentini, Simone Carradori, Cristiana Ercolani, Simonetta Buglioni, Daniela Secci, Massimiliano Andreazzoli, Donatella Del Bufalo and Daniela Trisciuoglio

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:103

    Content type: Research

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  31. Human papillomavirus (HPV)-positive oral squamous cell carcinoma (OSCC) is increasing worldwide with typically higher grade and stage, while better prognosis. microRNAs (miRNAs) has been shown to play a critic...

    Authors: Ming-xin Cao, Wei-long Zhang, Xiang-hua Yu, Jia-shun Wu, Xin-wei Qiao, Mei-chang Huang, Ke Wang, Jing-biao Wu, Ya-Jie Tang, Jian Jiang, Xin-hua Liang and Ya-ling Tang

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:102

    Content type: Research

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  32. Hepatoblastoma (HB) is a common liver malignancy in children. Our previous study has disclosed the crucial role of STAT3 (signal transducer and activator of transcription 3) in HB.

    Authors: Yanfeng Liu, Jianping Song, Yu Liu, Zhipeng Zhou and Xianqiang Wang

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:101

    Content type: Research

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  33. Human pluripotent embryonic stem cells have two special features: self-renewal and pluripotency. It is important to understand the properties of pluripotent stem cells and reprogrammed stem cells. One of the m...

    Authors: Kenly Wuputra, Chia-Chen Ku, Deng-Chyang Wu, Ying-Chu Lin, Shigeo Saito and Kazunari K. Yokoyama

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:100

    Content type: Review

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  34. Therapeutic options for patients with hepatocellular carcinoma (HCC) are limited. Transarterial chemoembolization (TACE) is an interventional procedure used to deliver chemotherapy and embolizing agents direct...

    Authors: Sean P. Martin, Valerie Fako, Hien Dang, Dana A. Dominguez, Subreen Khatib, Lichun Ma, Haiyang Wang, Wei Zheng and Xin Wei Wang

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:99

    Content type: Research

    Published on:

  35. The rising incidence of renal cell carcinomas (RCC) constitutes a significant challenge owing to risk of overtreatment. Because aberrant microRNA (miR) promoter methylation contributes to cancer development, w...

    Authors: Gonçalo Outeiro-Pinho, Daniela Barros-Silva, Elena Aznar, Ana-Isabel Sousa, Márcia Vieira-Coimbra, Jorge Oliveira, Céline S. Gonçalves, Bruno M. Costa, Kerstin Junker, Rui Henrique and Carmen Jerónimo

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:98

    Content type: Research

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  36. Hepatocellular carcinoma (HCC) is one of the most common malignancies today. Patients suffer from HCC since its high malignancy and limited treatment means. With the development of genetic research, new therap...

    Authors: Xiaoling Wu, Weijie Ma, Chengjie Mei, Xi Chen, Ye Yao, Yingyi Liu, Xian Qin and Yufeng Yuan

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:97

    Content type: Review

    Published on:

  37. Long intergenic non-protein coding RNA 520 (LINC00520), a novel identified lncRNA, has been shown to modulate the malignant phenotype of tumor cells in some malignant tumors. However, the exact role and molecu...

    Authors: Wenkang Luan, Yuting Ding, Haitao Yuan, Shaojun Ma, Hongru Ruan, Jinlong Wang, Feng Lu and Xuefeng Bu

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:96

    Content type: Research

    Published on:

  38. In a large number of cancer types, treatment selection depends on the presence of specific tumor biomarkers. Due to the dynamic nature of cancer, very often these predictive biomarkers are not uniformly presen...

    Authors: Marco Russano, Andrea Napolitano, Giulia Ribelli, Michele Iuliani, Sonia Simonetti, Fabrizio Citarella, Francesco Pantano, Emanuela Dell’Aquila, Cecilia Anesi, Nicola Silvestris, Antonella Argentiero, Antonio Giovanni Solimando, Bruno Vincenzi, Giuseppe Tonini and Daniele Santini

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:95

    Content type: Review

    Published on:

  39. Circular RNAs (circRNAs) have been associated with bladder cancer (BC), but the specific underlying molecular mechanism of their association with BC development has not been fully explored.

    Authors: Liang Chen, Xiong Yang, Jun Zhao, Ming Xiong, Raya Almaraihah, Zhaohui Chen and Teng Hou

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:94

    Content type: Research

    Published on:

  40. Doxorubicin is effective in a variety of solid and hematological malignancies. Unfortunately, clinical application of doxorubicin is limited due to a cumulative dose-dependent cardiotoxicity. Dihydrotanshinone...

    Authors: Xiaoping Wang, Qiyan Wang, Weili Li, Qian Zhang, Yanyan Jiang, Dongqing Guo, Xiaoqian Sun, Wenji Lu, Chun Li and Yong Wang

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:93

    Content type: Research

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  41. The RNA-binding protein Musashi-2 (MSI2) has been implicated in the tumorigenesis and tumor progression of some human cancers. MSI2 has also been reported to suppress tumor epithelial-to-mesenchymal transition...

    Authors: Ming Li, An-qi Li, Shu-ling Zhou, Hong Lv, Ping Wei and Wen-tao Yang

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:92

    Content type: Research

    Published on:

  42. Colorectal cancer (CRC) is one of the most common malignant tumors globally. Angiogenesis is a key event maintaining tumor cell survival and aggressiveness. The expression of vascular endothelial growth factor...

    Authors: Chen Chen, Zhiguo Huang, Xiaoye Mo, Yanmin Song, Xiangmin Li, Xiaogang Li and Mu Zhang

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:91

    Content type: Research

    Published on:

  43. ATP binding cassette subfamily A member 8 (ABCA8) belongs to the ATP binding cassette (ABC) transporter superfamily. ABCA8 is a transmembrane transporter responsible for the transport of organics, such as chol...

    Authors: Yifeng Cui, Shuhang Liang, Shugeng Zhang, Congyi Zhang, Yunzheng Zhao, Dehai Wu, Jiabei Wang, Ruipeng Song, Jizhou Wang, Dalong Yin, Yao Liu, Shangha Pan, Xirui Liu, Yan Wang, Jihua Han, Fanzheng Meng…

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:90

    Content type: Research

    Published on:

  44. Tumor-infiltrating immune cells play a key role against cancer. However, malignant cells are able to evade the immune response and establish a very complex balance in which different immune subtypes may drive ...

    Authors: Filippo Galli, Jesus Vera Aguilera, Belinda Palermo, Svetomir N. Markovic, Paola Nisticò and Alberto Signore

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:89

    Content type: Review

    Published on:

  45. Overexpression of survivin plays a crucial role in tumorigenesis and correlates with poor prognosis in human malignancies. Thus, survivin has been proposed as an attractive target for new anti-tumor interventi...

    Authors: Ming Li, Feng Gao, Xinfang Yu, Qing Zhao, Li Zhou, Wenbin Liu and Wei Li

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:88

    Content type: Research

    Published on:

  46. Prolactin receptor (PRLR) is highly expressed in a subset of human breast cancer and prostate cancer, which makes it a potential target for cancer treatment. In clinical trials, the blockade of PRLR was shown ...

    Authors: Yuexian Zhou, Huifang Zong, Lei Han, Yueqing Xie, Hua Jiang, John Gilly, Baohong Zhang, Huili Lu, Jie Chen, Rui Sun, Zhidi Pan and Jianwei Zhu

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:87

    Content type: Research

    Published on:

  47. The very limited time allowed to face the COVID-19 pandemic poses a pressing challenge to find proper therapeutic approaches. However, synthesis and full investigation from preclinical studies to phase III tri...

    Authors: Gennaro Ciliberto, Rita Mancini and Marco G. Paggi

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:86

    Content type: Review

    Published on:

  48. In acute myeloid leukemia (AML), internal tandem duplication mutations in the FLT3 tyrosine kinase receptor (FLT3-ITD) are associated with a dismal outcome. Although uncoordinated 51-like kinase 1 (ULK1), whic...

    Authors: Doh Yu Hwang, Ju-In Eom, Ji Eun Jang, Hoi-Kyung Jeung, Haerim Chung, Jin Seok Kim, June-Won Cheong and Yoo Hong Min

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:85

    Content type: Research

    Published on:

  49. Our previous studies have confirmed that cobalt chloride (CoCl2) can induce the formation of polyploid giant cancer cells (PGCCs), which is the key to the heterogeneity of solid tumors. PGCC formation is closely ...

    Authors: Kai Liu, Minying Zheng, Qi Zhao, Kexin Zhang, Zugui Li, Fangmei Fu, Hao Zhang, Jiaxing Du, Yuwei Li and Shiwu Zhang

    Citation: Journal of Experimental & Clinical Cancer Research 2020 39:83

    Content type: Research

    Published on:

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