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  1. Accumulating evidence indicates that circRNAs may serve as essential regulators in the progression of several human cancers, but the function and mechanism of circRNAs in intrahepatic cholangiocarcinoma (ICC) ...

    Authors: Ya-Ping Xu, Ze-Ning Dong, Si-Wei Wang, Yi-Min Zheng, Chi Zhang, Ying-Qun Zhou, Yu-Jie Zhao, Yan Zhao, Feng Wang, Rui Peng, Mao-Chun Tang, Dou-sheng Bai, Xiao-Yong Huang and Chuan-Yong Guo

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:290

    Content type: Research

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  2. The development of persistent endoplasmic reticulum (ER) stress is one of the cornerstones of prostate carcinogenesis; however, the mechanism is missing. Also, alcohol is a physiological ER stress inducer, and...

    Authors: Artem N. Pachikov, Ryan R. Gough, Caroline E. Christy, Mary E. Morris, Carol A. Casey, Chad A. LaGrange, Ganapati Bhat, Anatoly V. Kubyshkin, Iryna I. Fomochkina, Evgeniya Y. Zyablitskaya, Tatiana P. Makalish, Elena P. Golubinskaya, Kateryna A. Davydenko, Sergey N. Eremenko, Jean-Jack M. Riethoven, Amith S. Maroli…

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:289

    Content type: Research

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  3. Patients with advanced colorectal cancer (CRC) have a poor prognosis. Combinations of immunotherapies and anti-angiogenic agents are currently being evaluated in clinical trials. In this study, the multikinase...

    Authors: Dennis Doleschel, Sabine Hoff, Susanne Koletnik, Anne Rix, Dieter Zopf, Fabian Kiessling and Wiltrud Lederle

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:288

    Content type: Research

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  4. Emerging evidence demonstrates that lncRNAs play pivotal roles in tumor energy metabolism; however, the detailed mechanisms of lncRNAs in the regulation of tumor glycolysis remain largely unknown.

    Authors: Hongtao Liu, Qing Zhang, Yinsen Song, Yibin Hao, Yunxia Cui, Xin Zhang, Xueying Zhang, Yue Qin, Guangzhao Zhu, Feng Wang, Jinghan Dang, Shanshan Ma, Yanting Zhang, Wenna Guo, Shenglei Li, Fangxia Guan…

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:287

    Content type: Research

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  5. Scarce drug penetration in solid tumours is one of the possible causes of the limited efficacy of chemotherapy and is related to the altered tumour microenvironment. The abnormal tumour extracellular matrix (E...

    Authors: Lavinia Morosi, Marina Meroni, Paolo Ubezio, Ilaria Fuso Nerini, Lucia Minoli, Luca Porcu, Nicolò Panini, Marika Colombo, Barbara Blouw, David W. Kang, Enrico Davoli, Massimo Zucchetti, Maurizio D’Incalci and Roberta Frapolli

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:286

    Content type: Research

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  6. The recent discovery of immune checkpoint inhibitors is a significant milestone in cancer immunotherapy research. However, some patients with primary or adaptive drug resistance might not benefit from the over...

    Authors: Taofei Zeng, Yuqing Cao, Tianqiang Jin, Yu Tian, Chaoliu Dai and Feng Xu

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:285

    Content type: Review

    Published on:

  7. Chemotherapy resistance remains a barrier to improving the prognosis of epithelial ovarian cancer (EOC). ALKBH5 has recently been shown to be one of the RNA N6-methyladenosine (m6A) demethyltransferases associ...

    Authors: Sipei Nie, Lin Zhang, Jinhui Liu, Yicong Wan, Yi Jiang, Jing Yang, Rui Sun, Xiaolling Ma, Guodong Sun, Huangyang Meng, Mengting Xu and Wenjun Cheng

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:284

    Content type: Research

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  8. Successful colorectal cancer (CRC) therapy often depends on the accurate identification of primary tumours with invasive potential. There is still a lack of identified pathological factors associated with dise...

    Authors: Patrycja Przygodzka, Ewelina Sochacka, Kamila Soboska, Marcin Pacholczyk, Izabela Papiewska-Pająk, Tomasz Przygodzki, Przemysław Płociński, Steven Ballet, An De Prins and Joanna Boncela

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:283

    Content type: Research

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  9. Glioblastoma Multiforme (GBM) is a malignant primary brain tumor in which the standard treatment, ionizing radiation (IR), achieves a median survival of about 15 months. GBM harbors glioblastoma stem-like cell...

    Authors: Hyunkoo Kang, Sungmin Lee, Kyeongmin Kim, Jaewan Jeon, Seok-Gu Kang, HyeSook Youn, Hae Yu Kim and BuHyun Youn

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:282

    Content type: Research

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  10. 223Ra is currently used for treatment of metastatic castration resistant prostate cancer patients (mCRPC) bone metastases with fixed standard activity. Individualized treatments, based on adsorbed dose (AD) in ta...

    Authors: Rosa Sciuto, Sandra Rea, Sara Ungania, Antonella Testa, Valentina Dini, Maria Antonella Tabocchini, Clarice Patrono, Antonella Soriani, Valentina Palma, Raffaella Marconi and Lidia Strigari

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:281

    Content type: Research

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  11. Recurrent hepatocellular carcinoma (HCC) shows strong resistance to sorafenib, and the tumor-repopulating cells (TRCs) with cancer stem cell-like properties are considered a driver for its high recurrent rate ...

    Authors: Feng Qi, Wenxing Qin, Yao Zhang, Yongde Luo, Bing Niu, Quanlin An, Biwei Yang, Keqing Shi, Zhijie Yu, Junwei Chen, Xin Cao and Jinglin Xia

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:280

    Content type: Research

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  12. Dysregulated expression and activation of receptor tyrosine kinases (RTKs) are associated with a range of human cancers. However, current RTK-targeting strategies exert little effect on pancreatic cancer, a hi...

    Authors: Enliang Li, Xing Huang, Gang Zhang and Tingbo Liang

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:279

    Content type: Research

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  13. Glioblastoma multiforme (GBM), a lethal brain tumor, remains the most daunting challenge in cancer therapy. Overexpression and constitutive activation of PDGFs and PDGFRα are observed in most GBM; however, ava...

    Authors: Gong Peng, Yin Wang, Pengfei Ge, Christopher Bailey, Peng Zhang, Di Zhang, Zhaoli Meng, Chong Qi, Qian Chen, Jingtao Chen, Junqi Niu, Pan Zheng, Yang Liu and Yan Liu

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:278

    Content type: Research

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  14. Authors: Run-Wei Yang, Ying-Yue Zeng, Wen-Ting Wei, Yan-Mei Cui, Hui-Ying Sun, Yue-Long Cai, Xin-Xin Nian, Yun-Teng Hu, Yu-Ping Quan, Sheng-Lu Jiang, Meng Wang, Ya-Li Zhao, Jun-Feng Qiu, Ming-Xuan Li, Jia-Huan Zhang, Mei-Rong He…

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:277

    Content type: Retraction Note

    Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2016 35:152

  15. Leader cells are a subset of cancer cells that coordinate the complex cell-cell and cell-matrix interactions required for ovarian cancer migration, invasion, tumour deposition and are negatively associated wit...

    Authors: Nazanin Karimnia, Amy L. Wilson, Emma Green, Amelia Matthews, Thomas W. Jobling, Magdalena Plebanski, Maree Bilandzic and Andrew N. Stephens

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:276

    Content type: Research

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  16. Cold-inducible RNA binding protein (CIRP) is a newly discovered proto-oncogene. In this study, we investigated the role of CIRP in the progression of non-small cell lung cancer (NSCLC) using patient tissue sam...

    Authors: Yi Liao, Jianguo Feng, Weichao Sun, Chao Wu, Jingyao Li, Tao Jing, Yuteng Liang, Yonghui Qian, Wenlan Liu and Haidong Wang

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:275

    Content type: Research

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  17. Metastasis is most often the root cause of cancer-related death. Human short stature homeobox 2 (SHOX2), a homeodomain transcription factor, is a novel inducer of epithelial-to-mesenchymal transition in breast...

    Authors: Yong Teng, Reid Loveless, Elayne M Benson, Li Sun, Austin Y Shull and Chloe Shay

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:274

    Content type: Research

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  18. Expression of aberrant cyclin G2 is a key factor contributing to cancer biological processes, including glioma. However, the potential underlying mechanisms of cyclin G2 in the glioma tumor immune microenviron...

    Authors: Sen Li, Chenyang Zhao, Jinlan Gao, Xinbin Zhuang, Shuang Liu, Xuesha Xing, Qi Liu, Chen Chen, Shusen Wang and Yang Luo

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:273

    Content type: Research

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  19. Recent studies have investigated the role of circular RNAs (circRNAs) as significant regulatory factors in multiple cancer progression. Nevertheless, the biological functions of circRNAs and the underlying mec...

    Authors: Chaofan Peng, Yuqian Tan, Peng Yang, Kangpeng Jin, Chuan Zhang, Wen Peng, Lu Wang, Jiahui Zhou, Ranran Chen, Tuo Wang, Chi Jin, Jiangzhou Ji, Yifei Feng, Junwei Tang and Yueming Sun

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:272

    Content type: Research

    Published on:

  20. Epithelial ovarian cancer (EOC) is the most common gynecologic disorder. Even with the recent progresses made towards the use of new therapeutics, it still represents the most lethal gynecologic malignancy in ...

    Authors: Delphine Fessart, Jacques Robert, Cecile Hartog, Eric Chevet, Frederic Delom and Guillaume Babin

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:271

    Content type: Review

    Published on:

  21. Recent studies highlighted the increased frequency of AR-low or -negative prostate cancers (PCas) and the importance of AR-independent mechanisms in driving metastatic castration-resistant PCa (mCRPC) developm...

    Authors: Yakun Luo, Virginie Vlaeminck-Guillem, Silvère Baron, Sarah Dallel, Chang Xian Zhang and Muriel Le Romancer

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:270

    Content type: Research

    Published on:

  22. Cancer immunotherapy has gained attention as the supreme therapeutic modality for the treatment of various malignancies. Adoptive T-cell therapy (ACT) is one of the most distinctive modalities of this therapeu...

    Authors: Sasan Ghaffari, Nastaran Khalili and Nima Rezaei

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:269

    Content type: Review

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  23. Germ cell tumors (GCTs) are developmental cancers, tightly linked to embryogenesis and germ cell development. The recent and expanding field of RNA modifications is being increasingly implicated in such molecu...

    Authors: Vera Miranda-Gonçalves, João Lobo, Catarina Guimarães-Teixeira, Daniela Barros-Silva, Rita Guimarães, Mariana Cantante, Isaac Braga, Joaquina Maurício, Christoph Oing, Friedemann Honecker, Daniel Nettersheim, Leendert H. J. Looijenga, Rui Henrique and Carmen Jerónimo

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:268

    Content type: Research

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  24. Immune checkpoint molecules, also known as cosignaling molecules, are pivotal cell-surface molecules that control immune cell responses by either promoting (costimulatory molecules) or inhibiting (coinhibitory...

    Authors: Baokang Wu, Chongli Zhong, Qi Lang, Zhiyun Liang, Yizhou Zhang, Xin Zhao, Yang Yu, Heming Zhang, Feng Xu and Yu Tian

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:267

    Content type: Review

    Published on:

  25. Recently, a variety of clinical trials have shown that apatinib, a small-molecule anti-angiogenic drug, exerts promising inhibitory effects on multiple solid tumors, including non-small cell lung cancer (NSCLC...

    Authors: Chunfeng Xie, Xu Zhou, Chunhua Liang, Xiaoting Li, Miaomiao Ge, Yue Chen, Juan Yin, Jianyun Zhu and Caiyun Zhong

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:266

    Content type: Research

    Published on:

  26. Autophagy is an intracellular degradation system that removes unnecessary or dysfunctional components and recycles them for other cellular functions. Over the years, a mutual regulation between lipid metabolis...

    Authors: Francesca Ascenzi, Claudia De Vitis, Marcello Maugeri-Saccà, Christian Napoli, Gennaro Ciliberto and Rita Mancini

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:265

    Content type: Review

    Published on:

  27. Tumor resistance to apoptosis and the immunosuppressive tumor microenvironment are two major contributors to poor therapeutic responses during cancer intervention. Pyroptosis, a lytic and inflammatory programm...

    Authors: Reid Loveless, Ryan Bloomquist and Yong Teng

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:264

    Content type: Review

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  28. Mutant isocitrate dehydrogenase 1/2 (mIDH1/2) gain a novel function for the conversion of α-ketoglutarate (α-KG) to oncometabolite R-2-hydroxyglutarate (R-2-HG). Two molecular entities namely enasidenib (AG-221) ...

    Authors: Kun Yao, Hua Liu, Jiajun Yin, Jianmin Yuan and Hong Tao

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:263

    Content type: Review

    Published on:

  29. Liver cancer, mainly hepatocellular carcinoma, is one of the deadliest cancers worldwide and has a poor prognosis due to insufficient understanding of hepatocarcinogenesis. Previous studies have revealed that ...

    Authors: Juanjuan Luo, Chunjiao Lu, Meilan Feng, Lu Dai, Maya Wang, Yang Qiu, Huilu Zheng, Yao Liu, Li Li, Bo Tang, Chuan Xu, Yajun Wang and Xiaojun Yang

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:262

    Content type: Research

    Published on:

  30. Circular RNAs (circRNAs) are becoming a unique member of non-coding RNAs (ncRNAs) with emerging evidence of their regulatory roles in various cancers. However, with regards to pancreatic ductal adenocarcinoma ...

    Authors: Taoyue Yang, Peng Shen, Qun Chen, Pengfei Wu, Hao Yuan, Wanli Ge, Lingdong Meng, Xumin Huang, Yuzhe Fu, Yihan Zhang, Weikang Hu, Yi Miao, Zipeng Lu and Kuirong Jiang

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:261

    Content type: Research

    Published on:

  31. Oxaliplatin is one of the most commonly used chemotherapeutic agent for the treatment of various cancers, including gastric cancer. It has, however, a narrow therapeutic index due to its toxicity and the occur...

    Authors: Haiyong Zhang, Jing Wu, Jinqiu Yuan, Huafu Li, Yawei Zhang, Wang Wu, Wei Chen, Chunming Wang, Sijun Meng, Songyao Chen, Mingyu Huo, Yulong He and Changhua Zhang

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:260

    Content type: Research

    Published on:

  32. Despite marked advances in the clinical therapies, clinical outcome of most T-cell acute lymphoblastic leukemia (T-ALL) patients remains poor, due to the high risk of relapse, even after complete remission. Pr...

    Authors: Fangce Wang, Zheng Li, Jie Zhou, Guangming Wang, Wenjun Zhang, Jun Xu and Aibin Liang

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:259

    Content type: Research

    Published on:

  33. Human CUB and Sushi multiple domains 1 (CSMD1) is a large membrane-bound tumor suppressor in breast cancer. The current study aimed to elucidate the molecular mechanism underlying the effect of CSMD1 in highl...

    Authors: Chrysostomi Gialeli, Emre Can Tuysuz, Johan Staaf, Safia Guleed, Veronika Paciorek, Matthias Mörgelin, Konstantinos S. Papadakos and Anna M. Blom

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:258

    Content type: Research

    Published on:

  34. Based on previous studies highlighting that the induction of cyclooxygenase-2 (COX-2) and high prostaglandin E2 (PGE2) levels contribute to the pathogenesis of malignant pleural mesothelioma (MPM), and that ar...

    Authors: Barbara Nuvoli, Barbara Antoniani, Roberta Libener, Antonio Maconi, Andrea Sacconi, Mariantonia Carosi and Rossella Galati

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:257

    Content type: Research

    Published on:

  35. Treatment of renal cancer has significantly improved with the arrival to the clinic of kinase inhibitors and immunotherapies. However, the disease is still incurable in advanced stages. The fact that several a...

    Authors: Sara García-Alonso, Inés Romero-Pérez, Lucía Gandullo-Sánchez, Luis Chinchilla, Alberto Ocaña, Juan Carlos Montero and Atanasio Pandiella

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:256

    Content type: Research

    Published on:

  36. High-risk neuroblastoma patients have a 5-year survival rate of less than 50%. It’s an urgent need to identify new therapeutic targets and the appropriate drugs. Exportin-1 (XPO1), also known as chromosomal re...

    Authors: Lijia Pan, Cheng Cheng, Peiwen Duan, Kai Chen, Yeming Wu and Zhixiang Wu

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:255

    Content type: Research

    Published on:

  37. The incidence of renal cell carcinoma (RCC) is increasing worldwide with an approximate 20% mortality rate. The challenge in RCC is the therapy-resistance. Cancer resistance to treatment employs multiple mecha...

    Authors: Fengzhi Li, Ieman A. M. Aljahdali, Renyuan Zhang, Kent L. Nastiuk, John J. Krolewski and Xiang Ling

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:254

    Content type: Review

    Published on:

  38. Nuclear factor­κB (NF-κB) plays a vital role in hepatocellular carcinoma (HCC). β-arrestin1 (ARRB1) has been proved to enhance the activity of NF-κBp65, and our previous study indicated that ARRB1 promotes hep...

    Authors: Xuan Xu, Yiming Lei, Lingjun Chen, Haoxiong Zhou, Huiling Liu, Jie Jiang, Yidong Yang and Bin Wu

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:253

    Content type: Research

    Published on:

  39. Citation: Journal of Experimental & Clinical Cancer Research 2021 40:252

    Content type: Retraction Note

    Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2015 34:106

  40. Pancreatic cancer is a complex disease with a desmoplastic stroma, extreme hypoxia, and inherent resistance to therapy. Understanding the signaling and adaptive response of such an aggressive cancer is key to ...

    Authors: Silpa Gampala, Fenil Shah, Xiaoyu Lu, Hye-ran Moon, Olivia Babb, Nikkitha Umesh Ganesh, George Sandusky, Emily Hulsey, Lee Armstrong, Amber L. Mosely, Bumsoo Han, Mircea Ivan, Jing-Ruey Joanna Yeh, Mark R. Kelley, Chi Zhang and Melissa L. Fishel

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:251

    Content type: Research

    Published on:

  41. Primary liver cancer (PLC) is a common malignancy with high morbidity and mortality. Poor prognosis and easy recurrence on PLC patients calls for optimizations of the current conventional treatments and the ex...

    Authors: Yuanyuan Zheng, Yan Li, Jiao Feng, Jingjing Li, Jie Ji, Liwei Wu, Qiang Yu, Weiqi Dai, Jianye Wu, Yingqun Zhou and Chuanyong Guo

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:250

    Content type: Review

    Published on:

  42. Citation: Journal of Experimental & Clinical Cancer Research 2021 40:249

    Content type: Correction

    Published on:

    The original article was published in Journal of Experimental & Clinical Cancer Research 2019 38:38

  43. The identification of novel targets is of paramount importance to develop more effective drugs and improve the treatment of non-small cell lung cancer (NSCLC), the leading cause of cancer-related deaths worldw...

    Authors: Beatrice Parma, Vignesh Ramesh, Paradesi Naidu Gollavilli, Aarif Siddiqui, Luisa Pinna, Annemarie Schwab, Sabine Marschall, Shuman Zhang, Christian Pilarsky, Francesca Napoli, Marco Volante, Sophia Urbanczyk, Dirk Mielenz, Henrik Daa Schrøder, Marc Stemmler, Heiko Wurdak…

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:248

    Content type: Research

    Published on:

  44. Sarcomas are a very heterogeneous group of tumors with intrinsic developmental programs derived from the cell of origin. This implies a functional hierarchy inside tumors governed by sarcoma stem cells. Theref...

    Authors: Manuel Pedro Jimenez-García, Antonio Lucena-Cacace, Daniel Otero-Albiol and Amancio Carnero

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:247

    Content type: Research

    Published on:

  45. Head and neck squamous cell carcinoma (HNSCC) is heterogeneous in etiology, phenotype and biology. Patient-derived xenografts (PDX) maintain morphology and molecular profiling of the original tumors and have b...

    Authors: Daniel Strüder, Theresa Momper, Nina Irmscher, Mareike Krause, Jan Liese, Sebastian Schraven, Annette Zimpfer, Sarah Zonnur, Ann-Sophie Burmeister, Björn Schneider, Bernhard Frerich, Robert Mlynski, Christina Große-Thie, Christian Junghanss and Claudia Maletzki

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:246

    Content type: Research

    Published on:

  46. Ribosomal L1 domain-containing protein 1 (RSL1D1) is a nucleolar protein that is essential in cell proliferation. In the current opinion, RSL1D1 translocates to the nucleoplasm under nucleolar stress and inhib...

    Authors: Li Ding, Zhiping Zhang, Chenhong Zhao, Lei Chen, Zhiqiang Chen, Jie Zhang, Yaxian Liu, Yesen Nie, Yanzhi He, Kai Liao and Xinyue Zhang

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:245

    Content type: Research

    Published on:

  47. Tumor recurrence is one of the major challenges in clinical management of chordoma. Despite R0-resection, approximately 50% of chordomas recur within ten years after initial surgery. The underlying molecular p...

    Authors: Carolin Seeling, André Lechel, Michael Svinarenko, Peter Möller, Thomas F. E. Barth and Kevin Mellert

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:244

    Content type: Research

    Published on:

  48. Cellular senescence is a complex physiological state whose main feature is proliferative arrest. Cellular senescence can be considered the reverse of cell immortalization and continuous tumor growth. However, ...

    Authors: Daniel Otero-Albiol and Amancio Carnero

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:243

    Content type: Review

    Published on:

  49. Immunotherapeutic treatments are gaining attention due to their effective anti-tumor response. Particularly, the revolution of immune checkpoint inhibitors (ICIs) produces promising outcomes for various cancer...

    Authors: Krishnapriya M. Varier, Hemavathi Dhandapani, Wuling Liu, Jialei Song, Chunlin Wang, Anling Hu, Yaacov Ben-David, Xiangchun Shen, Yanmei Li and Babu Gajendran

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:242

    Content type: Review

    Published on:

  50. As competitive HMG-CoA reductase (HMGCR) inhibitors, statins not only reduce cholesterol and improve cardiovascular risk, but also exhibit pleiotropic effects that are independent of their lipid-lowering effec...

    Authors: Wen Jiang, Jin-Wei Hu, Xu-Ran He, Wei-Lin Jin and Xin-Yang He

    Citation: Journal of Experimental & Clinical Cancer Research 2021 40:241

    Content type: Review

    Published on:

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