Owned by the Association for International Promotion & Study in Tumors (APSIT)
miR-15a and miR-16-1 inhibit the proliferation of leukemic cells by down-regulating WT1 protein level
miR-15a and miR-16-1(miR-15a/16-1) have been implicated as tumor suppressors in chronic lymphocytic leukemia, multiple myeloma, and acute myeloid leukemic cells. However the mechanism of inhibiting the prolife...